CD40-CD40L interactions in atherosclerosis

article



Laman, J.D.

Meurs, M. van

Smet, B.J.G.L. de

Schoneveld, A.
The abundant presence of macrophages and activated T cells in atherosclerotic plaques suggests an active involvement of the immune system in this cardiovascular disease. However, insight into cellular interactions inducing relevant effector functions is still limited. Here, Jon Laman and colleagues propose that local interactions between CD40 and CD40 ligand may induce multiple activities by different cell types contributing to atherosclerosis. Chemicals/CAS: Antigens, CD40; CD40 Ligand, 147205-72-9; Ligands; Membrane Glycoproteins
Topics












Cd40 antigenGlycoprotein gp 39Atherosclerotic plaqueImmunologyT lymphocyte activationAnimalsAntigens, CD40ArteriosclerosisCD40 LigandHumansLigandsMembrane GlycoproteinsProtein Binding
TNO Identifier
233928
Repository link
https://resolver.tno.nl/uuid:fad1f32f-543b-4dd1-8a42-31a1a084b292
ISSN
01675699
Source
Immunology Today, 18(6), pp. 272-277.
Pages
272-277
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