The radial immunodiffusion assay for plasma Histidine-rich Glycoprotein (HRG) based on a polyclonal antibody, shows a different specificity towards the two variants of a common amino acid polymorphism

article


Hennis, B.C.

Hoffmann, J.J.M.L.

Kluft, C.
Recently, two molecular weight forms of Histidine-rich Glycoprotein have been described which explain 59% of the variation in plasma HRG levels. Here, we demonstrate that this can partly be ascribed to a difference in specificity of the immuno assay for HRG towards the two alleles of the polymorphism.
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amino acidglycoproteinhistidine rich glycoproteinpolyclonal antibodyunclassified drugconference papercontrolled studygenetic polymorphismhumanimmunoassayimmunodiffusionpriority journalrisk factorthrombosis
TNO Identifier
233518
Repository link
https://resolver.tno.nl/uuid:5477aec6-fd9b-4c0f-b12c-170470391e49
ISSN
02689499
Source
Fibrinolysis, 10(SUPPL. 2), pp. 133-134.
Pages
133-134
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