A novel method, COAMATIC® plasmin inhibitor, for the specific determination of Plasmin Inhibitor activity in plasma
article
A new automated method, COAMATIC® Plasmin Inhibitor, provides a tool for specific determination of Plasmin Inhibitor activity in plasma. The method is adapted to the ACL 300R, Cobas Mira, MLA 1000C and to the Thrombolyzer. Low plasmin concentrations combined with short incubation times ensure good specificity also in the low range, resulting in a value of < 6% when analysing a Plasmin Inhibitor deficient plasma. The method is shown to be insensitive to α2-Macroglobulin. Finally, the COAMATIC Plasmin Inhibitor method shows a promising correlation with the Immediate Plasmin Inhibition Test (IPIT)-method.
TNO Identifier
233513
ISSN
02689499
Source
Fibrinolysis, 10(SUPPL. 2), pp. 165-167.
Pages
165-167
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