Enhanced surface plasmon resonance inhibition test (ESPRIT) using latex particles
article
The pregnancy hormone human chorionic gonadotropin (hCG) was used as a model antigen to describe a new assay, the Enhanced Surface Plasmon Resonance Inhibition Test (ESPRIT). It was shown that the introduction of sub-micron latex particles instead of anti-antibodies in an enhancement step improved the sensitivity of the assay by a factor of 30. Latex particles are therefore considered to be versatile tools in the development of new immunochemical assays for the detection of any analyte using SPR immunosensors.
The pregnancy hormone human chorionic gonadotropin (hCG) was used as a model antigen to describe a new assay, the Enhanced Surface Plasmon Resonance Inhibition Test (ESPEIT). It was shown that the introduction of sub-micron latex particles instead of anti-antibodies in an enhancement step improved the sensitivity of the assay by a factor of 30. Latex particles are therefore considered to be versatile tools in the development of new immunochemical assays for the detection of any analyte using SPR immunosensors.
Chemicals/CAS: chorionic gonadotropin, 9002-61-3.
The pregnancy hormone human chorionic gonadotropin (hCG) was used as a model antigen to describe a new assay, the Enhanced Surface Plasmon Resonance Inhibition Test (ESPEIT). It was shown that the introduction of sub-micron latex particles instead of anti-antibodies in an enhancement step improved the sensitivity of the assay by a factor of 30. Latex particles are therefore considered to be versatile tools in the development of new immunochemical assays for the detection of any analyte using SPR immunosensors.
Chemicals/CAS: chorionic gonadotropin, 9002-61-3.
Topics
TNO Identifier
80864
Source
Biosensors & Bioelectronics, 8(7-8), pp. 365-370.
Pages
365-370
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