Gas chromatographic determination of chlorothalonil and its metabolite 4-hydroxy-2,5,6-trichloroisophtalonitrile (HTI) in water
article
A gas chromatographic method, with electron capture detection and mass spectrometric confirmation, is described for the determination of chlorothalonil and its metabolite 4-hydroxy-2,5,6-trichloroisophtalonitrile (HTI) in water samples. Water is saturated with sodium chloride and acidified to pH < 2 with dilute sulfuric acid. After extraction with dichloromethane, HTI was methylated with diazomethane. The extract obtained was cleaned with basic alumina. Chlorothalonil and the methylated HTI-derivative were determined by gas chromatography with electron capture detection (GC-ECD) and confirmed by gas chromatography-mass spectrometry (GC-MS). The limit of detection, depending on the nature of the water samples is for both compounds between 0.01-0.03 μg l-1 water. The average recovery in ground water is 87% for chlorothalonil and 82% for HTI.
Topics
TNO Identifier
232878
ISSN
00095893
Source
Chromatographia, 40(7-8), pp. 458-462.
Pages
458-462
Files
To receive the publication files, please send an e-mail request to TNO Repository.