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Gart, E. (author), van Duyvenvoorde, W. (author), Snabel, J. (author), de Ruiter, C. (author), Attema, J. (author), Caspers, M.P.M. (author), Lek, S. (author), van Heuven, B.J. (author), Speksnijder, A.G.C.L. (author), Giera, M. (author), Menke, A. (author), Salic, K. (author), Bence, K.K. (author), Tesz, G.J. (author), Keijzer, J. (author), Kleemann, R. (author), Morrison, M.C. (author)
Background: NAFLD progression, from steatosis to inflammation and fibrosis, results from an interplay of intra- and extrahepatic mechanisms. Disease drivers likely include signals from white adipose tissue (WAT) and gut. However, the temporal dynamics of disease development remain poorly understood. Methods: High-fat-diet (HFD)-fed Ldlr-/-...
article 2023
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Viera, J. (author), Aguilar, J. (author), Rodriguez-Moreno, M. (author), Quintero-Gull, C. (author)
Analyzing energy consumption is currently of great interest to define efficient energy management strategies. In particular, studying the evolution of the behavior of the consumption pattern can allow energy policies to be defined according to the time of the year. In this sense, this work proposes to study the evolution of energy behavior...
article 2023
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Bottenheft, C. (author), Groen, E.L. (author), Mol, D. (author), Valk, P.J.L. (author), Houben, M.M.J. (author), Kingma, B.R.M. (author), van Erp, J.B.F. (author)
This study investigates how cognitive performance is affected by the combination of two stressors that are operationally relevant for helicopter pilots: heat load and hypobaric hypoxia. Fifteen participants were exposed to: 1) no stressors, 2) heat load, 3) hypobaric hypoxia and 4) combined heat load and hypobaric hypoxia. Hypobaric hypoxia (13...
article 2023
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Villani, M.L. (author), de Nicola, A. (author), Bouma, H. (author), van Rooijen, A. (author), Räsänen, P. (author), Peltola, J. (author), Toivonen, S. (author), Guarneri, M. (author), Stifini, C. (author), de Dominicis, L. (author)
Preventing terrorist attacks at soft targets has become a priority for our society. The realiza tion of sensor systems for automatic threat detection in crowded spaces, such as airports and metro stations, is challenged by the limited sensing coverage capability of the devices in place due to the variety of dangerous materials, to the scanning...
article 2023
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Wilmes, L. (author)
report 2023
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Adhikari, A. (author), Vethman, S. (author), van Genabeek, J.A.G.M. (author)
Skills-based recruitment is fostered in the Netherlands by various initiatives1. The skills-based approach aims to create a better fit between those looking for a job (candidates) and those offering a job (employers) by means of focusing on the skills necessary to excel at the job. The assumption is that a focus on skills mitigates...
report 2023
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de Gier, J. (author), Bergmans, J. (author), Hildmann, H. (author)
A generic reasoning approach for autonomous unmanned vehicle (UxV) mission execution is presented. The system distinguishes (a) mission planning and (b) mission execution, treating these as separate but closely interdependent stages. The context of the work is that of tactical military operations, and the focus of the current (simulated)...
article 2023
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Santonen, T. (author), Mahiout, S. (author), Alvito, P. (author), Apel, P. (author), Bessems, J. (author), Bil, W. (author), Borges, T. (author), Bose-O'Reilly, S. (author), Buekers, J. (author), Canas Portilla, A.I. (author), Calvo, A.C. (author), de Alba González, M. (author), Dominguez-Morueco, N. (author), Lopez, M.E. (author), Falnoga, I. (author), Gerofke, A. (author), Caballero, M.D.C.G. (author), Horvat, M. (author), Huuskonen, P. (author), Kadikis, N. (author), Kolossa-Gehring, M. (author), Lange, R. (author), Louro, H. (author), Martins, C. (author), Meslin, M. (author), Niemann, L. (author), Diaz, S.P. (author), Plichta, V. (author), Porras, S.P. (author), Rousselle, C. (author), Scholten, B. (author), Silva, M.J. (author), Šlejkovec, Z. (author), Tratnik, J.S. (author), Joksic, A.Š. (author), Tarazona, J.V. (author), Uhl, M. (author), van Nieuwenhuyse, A. (author), Viegas, S. (author), Vinggaard, A.M. (author), Woutersen, M. (author), Schoeters, G. (author)
One of the aims of the European Human Biomonitoring Initiative, HBM4EU, was to provide examples of and good practices for the effective use of human biomonitoring (HBM) data in human health risk assessment (RA). The need for such information is pressing, as previous research has indicated that regulatory risk assessors generally lack knowledge...
article 2023
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Kirchherr, J. (author), Hartley, K. (author), Tukker, A. (author)
The concept of ‘sustainability missions’ has recently received increasing attention in the academic literature. Broadly defined as a collective ambition to strengthen systemic preparedness and adaptive capacity for various policy challenges, the concept of sustainability missions invites critical reflection due to its rise in usage and...
article 2023
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Paquelet Wuetz, B. (author), Degli Esposti, D. (author), Zwerver, A.M.J. (author), Amitonov, S.V. (author), Botifoll, M. (author), Arbiol, J. (author), Vandersypen, L.M.K. (author), Russ, M. (author), Scappucci, G. (author)
Charge noise in the host semiconductor degrades the performance of spinqubits and poses an obstacle to control large quantumprocessors. However, it is challenging to engineer the heterogeneous material stack of gate-defined quantum dots to improve charge noise systematically. Here, we address the semiconductor-dielectric interface and the buried...
article 2023
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Harakeh, Z. (author), de Hoogh, I.M. (author), van Keulen, H. (author), Kalkman, G. (author), van Someren, E. (author), van Empelen, P. (author), Otten, W. (author)
Background: Various multifaceted factors need to be addressed to improve the health and quality of life of people with type 2 diabetes (T2D). Therefore, we developed a web-based decision support tool that comprises a more holistic diagnosis (including 4 domains: body, thinking and feeling, behavior, and environment) and personalized advice. This...
article 2023
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Malvar, O. (author), Gil-Santos, E. (author), Ruz, J.J. (author), Sentre-Arribas, E. (author), Sanz-Jimenez, A. (author), Kosaka, P.M. (author), Garcia-Lopez, S. (author), Paulo, A.S. (author), Sbarra, S. (author), Waquier, L. (author), Favero, I. (author), Van Der Heiden, M. (author), Altmann, R.K. (author), Papanastasiou, D. (author), Kounadis, D. (author), Panagiotopoulos, I. (author), Mingorance, J. (author), Rodriguez-Tejedor, M. (author), Delgado, R. (author), Calleja, M. (author), Tamayo, J. (author)
Nanomechanical mass spectrometry allows characterization of analytes with broad mass range, from small proteins to bacterial cells, and with unprecedented mass sensitivity. In this work, we show a novel multifrequency nanomechanical mass spectrometer prototype designed for focusing, guiding and soft-landing of nanoparticles and viral particles...
conference paper 2023
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Campero Jurado, I. (author), Lorato, I. (author), Morales, J. (author), Fruytier, L. (author), Stuart, S. (author), Panditha, P. (author), Janssen, D. (author), Rossetti, N. (author), Uzunbajakava, N. (author), Serban, I. (author), Rikken, L. (author), de Kok, M. (author), Vanschoren, J. (author), Brombacher, A. (author)
Cardiovascular diseases (CVD) represent a serious health problem worldwide, of which atrial fibrillation (AF) is one of the most common conditions. Early and timely diagnosis of CVD is essential for successful treatment. When implemented in the healthcare system this can ease the existing socio-economic burden on health institutions and...
article 2023
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Wang, F. (author), Kooij, R. (author)
Network controllability and its robustness has been widely studied. However, analytical methods to calculate network controllability with respect to node removals are currently lacking. This paper develops methods, based upon generating functions for the in- and out-degree distributions, to approximate the minimum number of driver nodes needed...
conference paper 2023
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Paquelet Wuetz, B. (author), Degli Esposti, D. (author), Zwerver, A.M.J. (author), Amitonov, S.V. (author), Botifoll, M. (author), Arbiol, J. (author), Vandersypen, L.M.K. (author), Russ, M. (author), Scappucci, G. (author)
Charge noise in the host semiconductor degrades the performance of spin-qubits and poses an obstacle to control large quantum processors. However, it is challenging to engineer the heterogeneous material stack of gate-defined quantum dots to improve charge noise systematically. Here, we address the semiconductor-dielectric interface and the...
article 2023
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Lindner, C. (author), Looijesteijn, E. (author), van Dijck, H. (author), Bovee-Oudenhoven, I. (author), Heerikhuisen, M. (author), van den Broek, T.J. (author), Marzorati, M. (author), Triantis, V. (author), Nauta, A. (author)
The objective of the current study was to evaluate the potential of 2′-FL and GOS, individually and combined, in beneficially modulating the microbial composition of infant and toddler (12–18 months) feces using the micro-Matrix bioreactor. In addition, the impacts of GOS and 2′-FL, individually and combined, on the outgrowth of fecal...
article 2023
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Meima, M.Y. (author), Fransman, W. (author), Ziniel, G. (author), Breindl, G. (author)
The Roadmap on Carcinogens aims to create awareness on occupational exposure to carcinogens, and ultimately provide innovative approaches to reduce exposure. One of the challenges of this roadmap (Challenge 4.2) is to get more grip on carcinogens created as a by-product during a work process, so called processgenerated carcinogens (PGCs). As...
report 2023
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Preenen, P. (author)
Edited by Kenneth Abrahamsson and Richard Ennals (2022) Publisher: Peter Lang, Berlin. Many relevant books, reports and publications about sustainable work and quality of work have been written. However, the book Sustainable Work in Europe: Concepts, Conditions, Challenges, edited by Kenneth Abrahamsson and Richard Ennals may be more needed than...
article 2023
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Meima, M.Y. (author), Fransman, W. (author)
The Roadmap on Carcinogens aims to create awareness on occupational exposure to carcinogens, and ultimately provide innovative approaches to reduce exposure. One of the challenges of this roadmap (Challenge 4.3) is to gather results, bring together stakeholders and promote the development of SWPs. The current report aims to summarize the status...
report 2023
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Landman, A. (author), Mol, D. (author), van Emmerik, M.L. (author), van Groen, E.L. (author)
In this simulator study, we investigated the potential negative transfer of training that may result from situations where a correct decision made by the trainee is being overruled by the instructor to save training time. We hypothesized that discarding a correct decision in a training situation can introduce confusion when the trainee...
report 2023
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