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van Wier, M.F. (author), Ariëns, G.A.M. (author), Dekkers, J.C. (author), Hendriksen, I.J.M. (author), Pronk, N.P. (author), Smid, T. (author), van Mechelen, W. (author), TNO Kwaliteit van Leven (author)
Background: The prevalence of overweight is increasing and its consequences will cause a major public health burden in the near future. Cost-effective interventions for weight control among the general population are therefore needed. The ALIFE@Work study is investigating a novel lifestyle intervention, aimed at the working population, with...
article 2006
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Groothuis-Oudshoorn, C.G.W. (author), Chorus, A.M.J. (author), van Beekum, W.T. (author), Detmar, S.B. (author), van den Hout, W.B. (author), TNO Kwaliteit van Leven (author)
article 2006
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Martens, M. (author), van Assema, P. (author), Paulussen, T. (author), Schaalma, H. (author), Brug, J. (author), TNO Preventie en Gezondheid (author)
The aim of this study was to examine the fidelity and completeness of the implementation of a school-based healthful diet promotion programme called 'Krachtvoer' (we use the Dutch title of the programme throughout this article. A possible translation is Power Food, but this does not reflect the play on words in the Dutch title), aimed at lower...
article 2006
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Steenstra, I.A. (author), Verbeek, J.H. (author), Prinsze, F.J. (author), Knol, D.L. (author), TNO Kwaliteit van Leven (author)
Background: Back pain (including neck pain) is one of the most prevalent health problems for which physicians are consulted. Back pain can decrease the quality of life considerably during a great part of the lives of those who suffer from it. At the same time it has an enormous economic impact, mainly through sickness absence and long-term...
article 2006
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van Leerdam, F.J.M. (author), Reijneveld, S.A. (author), de Hoog, N. (author), van der Heijden, A.J. (author), Hirasing, R.A. (author)
Aim of the study was to assess the prevalence of daytime and/or night-time incontinence in children with a clinical score on Attention Problems. Of the population sample of 4970 children, 4480 participated (response 90.1%). Parents of 4171 children (2069 boys and 2102 girls) aged between 4 and 15 years filled out the Dutch version of the Child...
article 2005
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Vrijlandt, E.J.L.E. (author), Gerritsen, J. (author), Boezen, H.M. (author), Duiverman, E.J. (author), Hille, E.T.M. (author), de Groot, C.H. (author), Kloosterboer-Boerrigter, H. (author), den Ouden, A.L. (author), Rijpstra, A. (author), Verloove-Vanhorick, S.P. (author), Vogelaar, J.A. (author), Kok, J.H. (author), Ilsen, A. (author), van der Lans, M. (author), van der Boelen - Loo, W.J.C. (author), Lundqvist, T. (author), Heymans, H.S.A. (author), Geven, W.B. (author), Duiverman, M.L. (author), Geven, L.I. (author), Mulder, A.L.M. (author), Gerver, A. (author), Kollée, L.A.A. (author), Reijmers, L. (author), Sonnemans, R. (author), Wit, J.M. (author), Dekker, F.W. (author), Finken, M.J.J. (author), Weisglas-Kuperus, N. (author), Keijzer-Veen, M.G. (author), van der Heijden, A.J. (author), van Goudoever, J.B. (author), van Weissenbruch, M.M. (author), Cranendonk, A. (author), van de Delemarre - Waal, H.A. (author), de Groot, L. (author), Samsom, J.F. (author), de Vries, L.S. (author), Rademaker, K.J. (author), Moerman, E. (author), Voogsgeerd, M. (author), de Kleine, M.J.K. (author), Andriessen, P. (author), van Dielissen - Helvoirt, C.C.M. (author), Mohamed, I. (author), van Straaten, H.L.M. (author), Baerts, W. (author), Veneklaas Slots-Kloosterboer, G.W. (author), Tuller-Pikkemaat, E.M.J. (author), Ens-Dokkum, M.H. (author), van Steenbrugge, G.J. (author), TNO Kwaliteit van Leven (author)
Objective: To study the prevalence of respiratory and atopic symptoms in (young) adults born prematurely, differences between those who did and did not develop Bronchopulmonary Disease (BPD) at neonatal age and differences in respiratory health between males and females. Methods: Design: Prospective cohort study. Setting: Nation wide follow-up...
article 2005
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Hoozemans, M.J.M. (author), de Looze, M.P. (author), Kingma, I. (author), Reijneveld, K.C.N. (author), de Korte, E.M. (author), van der Grinten, M.P. (author), van Dieën, J.H. (author), TNO Kwaliteit van Leven (author)
The objective of the present study was to compare energetic workload, perceived exertion, perceived discomfort, safety, and mechanical load at lower limb joints among window cleaners during usage of extension ladders with 30 and 35 cm rung separation. Eleven healthy male professional window cleaners of short and tall stature participated in this...
article 2005
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Kamphuis, M. (author), Vliegen, H.W. (author), Verloove-Vanhorick, S.P. (author), Ottenkamp, J. (author), Vogels, T. (author)
Objective. To evaluate employment, career problems and job-related handicaps in adults with complex or mild congenital heart disease (CHD). Design. Cross-sectional. Method. Data were obtained from 76 patients with complex and 80 with mild CHD who were known to the Department of Paediatric Cardiology at the Leiden University Medical Center, the...
article 2005
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Knops, N.B.B. (author), Sneeuw, K.C.A. (author), Brand, R. (author), Hille, E.T.M. (author), den Ouden, A.L. (author), Wit, J.M. (author), Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)
Background: Improved survival due to advances in neonatal care has brought issues such as postnatal growth and development more to the focus of our attention. Most studies report stunting in children born very preterm and/or small for gestational age. In this article we study the growth pattern of these children and aim to identify factors...
article 2005
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Kummeling, I. (author), Thijs, C. (author), Penders, J. (author), Snijders, B.E.P. (author), Stelma, F. (author), Reimerink, J. (author), Koopmans, M. (author), Dagnelie, P.C. (author), Huber, M. (author), Jansen, M.C.J.F. (author), de Bie, R. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven TNO Voeding (author)
The aim of the KOALA Birth Cohort Study in the Netherlands is to identify factors that influence the clinical expression of atopic disease with a main focus on lifestyle (e.g., anthroposophy, vaccinations, antibiotics, dietary habits, breastfeeding and breast milk composition, intestinal microflora composition, infections during the first year...
article 2005
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de Raad, J. (author), Nijhuis, F.J.N. (author), Willems, J.H.B.M. (author), TNO Preventie en Gezondheid (author)
In 1998, the Royal Netherlands Army introduced a new examination system (abbreviated as BMEKL), which was based on the "workload-capability" model, to replace the old system (abbreviated as PULHEEMS), which focused on diagnosis and was based solely on the detection of diseases and infirmities. To discern differences under operational conditions...
article 2005
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Reijneveld, S.A. (author), Brugman, E. (author), Verhulst, F.C. (author), Verloove-Vanhorick, S.P. (author)
Objective. To assess the degree to which preventive child health professionals (CHPs) identify and manage psychosocial problems among pre-school children in the general population, and to determine its association with parent-reported behavioral and emotional problems, sociodemographic factors and (mental) health history of children. Design....
article 2005
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Fox, T.E. (author), van den Heuvel, E.G.H.M. (author), Atherton, C.A. (author), Dainty, J.R. (author), Lewis, D.J. (author), Langford, N.J. (author), Crews, H.M. (author), Luten, J.B. (author), Lorentzen, M. (author), Sieling, F.W. (author), van Aken-Schneyder, P. (author), Hoek, M. (author), Kotterman, M.J.J. (author), van Dael, P. (author), Firweather-Tail, S.J. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective: To measure the bioavailability of selenium from cooked and raw fish in humans by estimating and comparing apparent absorption and retention of selenium in biosynthetically labelled fish with labelled selenate and biosynthetically labelled selenium in brewers yeast. Design: The intervention study was a parallel, randomised, reference...
article 2004
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Davidse, W. (author), Perenboom, R.J.M. (author), TNO Preventie en Gezondheid (author)
Chemicals / CAS: naproxen, 22204-53-1, 26159-34-2
article 2004
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Lüchtenborg, M. (author), Weijenberg, M.P. (author), Roemen, G.M.J.M. (author), de Bruïne, A.P. (author), van den Brandt, P.A. (author), Lentjes, M.H.F.M. (author), Brink, M. (author), van Engeland, M. (author), Goldbohm, R.A. (author), de Goeij, A.F.P.M. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)
The adenomatous polyposis coli (APC) gene is considered to be a gatekeeper in colorectal tumourigenesis. Inactivating mutations in APC have been reported in 34-70% of sporadic colorectal cancer patients, the majority of which occur in the mutation cluster region (MCR). In this study, tumour tissue from 665 incident colorectal cancer patients,...
article 2004
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de Lange, A.H. (author), Taris, T.W. (author), Kompier, M.A.J. (author), Houtman, I.L.D. (author), Bongers, P.M. (author), TNO Arbeid (author)
This longitudinal study examined the causal relationships between job demands, job control and supervisor support on the one hand and mental health on the other. Whereas we assumed that work characteristics affect mental health, we also examined reversed causal relationships (mental health influences work characteristics). Further, the topic of...
article 2004
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Proper, K. (author), Hildebrandt, V. (author), van der Beek, A. (author), Green, B.B. (author)
Chemicals/CAS: cholesterol, 57-88-5
article 2003
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van der Plas, S.M. (author), Hansen, B.E. (author), de Boer, J.B. (author), Stijnen, T. (author), Passchier, J. (author), de Man, R.A. (author), Schalm, S.W. (author), TNO Kwaliteit van Leven (author)
Background: Studies on Health Related Quality of Life (HRQoL) of chronic liver patients were performed in clinical populations. These studies included various disease stages but small variations in aetiology and no transplanted patients. We performed a large HRQoL study in non-cirrhotic, cirrhotic and transplanted liver patients with sufficient...
article 2003
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Witte, D.R. (author), Broekmans, W.M.R. (author), Kardinaal, A.F.M. (author), Klöpping-Ketelaars, I.A.A. (author), van Poppel, G. (author), Bots, M.L. (author), Kluft, C. (author), Princen, J.M.G. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
Background: Flow mediated dilatation (FMD) of the brachial artery and soluble intercellular adhesion molecule 1 (sICAM-1) are measures of distinct functions of the endothelium, reflecting nitric oxide (NO)-mediated and pro-inflammatory status, respectively. The comparative value of the two measures in relation to cardiovascular risk is unknown....
article 2003
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Reijneveld, S.A. (author), Crone, M.R. (author), Verhulst, F.C. (author), Verloove-Vanhorick, S.P. (author)
Objective. To examine the effects of a catastrophe on the mental health of adolescents using prospective data from before and after the catastrophe. Design. Prospective, comparative. Method. The Volendam café fire wounded about 250 adolescents, of whom 14 died. In September and October 1999, 15 months before the catastrophe, all grade 2 pupils...
article 2003
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