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Hirasing, R.A. (author), Donckerwolcke, R.A.M.G. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)Om een indruk te krijgen van de wijze van bloeddrukmeting en de criteria voor het stellen van de diagnose hypertensie in de praktijk van de jeugdgezondheidszorg werd in 1989 een schriftelijke enquête gehouden onder een aselecte steekproef van 100 schoolartsen. De respons bedroeg 62. De resultaten lieten grote verschillen in zowel methoden van...article 1991
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Korteling, J.E. (author)Age-related differences in dual-task performance may be affected by factors such as skill integration and perceptual competition. Therefore these factors were examined in a dual-task experiment with young and older adults involving two one-dimensional compensatory tracking tasks. Single-task difficulty was individually adjusted for each subject....article 1991
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Dooijewaard, G. (author), de Boer, A. (author), Turion, P.N.C. (author), Cohen, A.F. (author), Breimer, D.D. (author), Kluft, C. (author), Gaubius Instituut TNO (author)The enhancement of the blood fibrinolytic potential by physical exercise is generally attributed to the release of tissue-type plasminogen activator (t-PA) from the vessel wall. In this study we have investigated the possible contribution of urokinase-type plasminogen activator (u-PA). Six healthy male volunteers (age 21-25 years) were screened...article 1991
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- Hirasing, R.A. (author), Reerink, J.D. (author), de Vrind, S. (author), Verloove-Vanhorick, S.P. (author), TNO Preventie en Gezondheid (author) article 1991
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Roholl, P.J.M. (author), Weima, S.M. (author), Prinsen, I. (author), de Weger, R.A. (author), den Otter, W. (author), van Unnik, J.A.M. (author), Instituut voor Verouderings- en Vaatziekten Onderzoek TNO Instituut voor Experimentele Gerontologie TNO (author)The expression of both platelet-derived growth factor (PDGF) and epidermal growth factor (EGF), and of their receptors was examined immunohistochemically in a number of normal tissues as well as in benign and malignant mesenchymal tumors. The benign lesions studied were from the skin: palmar fibromatosis (fibroblastic) and from the uterus:...article 1991
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- Schaapveld, K. (author), van de Water, H.P.A. (author), van Ginneken, J.K.S. (author) article 1991
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- Hirasing, R.A. (author), Reus, H. (author), TNO Preventie en Gezondheid (author) article 1991
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- van de Laar, M.J.W. (author), Sleutjes, M.P.M. (author), Postema, C.A. (author), van de Water, H.P.A. (author) article 1991
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Daanen, H.A.M. (author), Ducharme, M.B. (author)Five subjects immersed their hands and feet twice during 1 hour sessions in a calorimeter bath, filled with water at 25 degrees C. Before immersion the hand (33.0 +/- 2.2 degrees C) was warmer than the foot (30.6 +/- 2.1 degrees C) and so was the blood flow: respectively 5.8 +/- 5.2 versus 0.7 +/- 0.3 ml.min-1.100 mo tissue-1 as determined by...article 1991
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Gaubius Instituut TNO (author), Atsma, D.E. (author), Kempen, H.J.M. (author), Nieuwenhuizen, W. (author), van 't Hooft, F.M. (author), Pauwels, E.K.J. (author)Four 99mTc and three 123I labeling methods were evaluated for their suitability to label low density lipoproteins (LDL) for the purpose of scintigraphic biodistribution studies. For 99mTc these methods were: direct incorporation in LDL of 99mTcO4- using sodium dithionite (dithionite method); a method using first N,N-dimethylformamide to prepare...article 1991
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Gaubius Instituut TNO (author), de Knijff, P. (author), van den Maagdenberg, A.M.J.M. (author), Stalenhoef, A.F.H. (author), Leuven, J.A.G. (author), Demacker, P.N.M. (author), Kuyt, L.P. (author), Frants, R.R. (author), Havekes, L.M. (author)By the careful screening of familial dysbetalipoproteinemic (FD) patients, five probands showing heterozygosity for the APOE*3-Leiden allele were found. Genealogical studies revealed that these probands share common ancestry in the 17th century. In a group of 128 family members, spanning three generations, 37 additional heterozygous APOE*3...article 1991
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Centraal Instituut voor Voedingsonderzoek TNO (author), Torre H.W.van der, (author), van Dokkum, W. (author), Schaafsma, G. (author), Wedel, M. (author), Ockhuizen, T. (author)After a 5-week period of low selenium intake, twenty-four Dutch men received 55, 135 or 215 ug Se/d as Se-rich meat or bread for a 9-week period. Four unsupplemented subjects served as controls. Plasma Se increased more rapidly than erythrocyte Se levels; the increases were significantly dependent (P < 0.001) on Se intake level. Glutathione...article 1991
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Medisch Biologisch Laboratorium TNO (author), de Kort, W.L.A.M. (author), Fransman, L.G. (author), van Dijk, F.J.H. (author)Several hundreds of thousands of preemployment medical examinations are performed in The Netherlands each year, with the objective of screening for obvious risks for the applicants or others. Neither the efficacy of these examinations nor determinants for rejection are known. Altogether 101,754 preemployment medical examinations of applicants...article 1991
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Instituut CIVO-Toxicologie en Voeding TNO (author), Poppel, G.van. (author), Schneijder, P. (author), Löwik, M.R.H. (author), Schrijver, J. (author), Kok, F.J. (author)As part of the Dutch Nutrition Surveillance System, cardiovascular risk factors and food consumption (24 h recall) as well as haematological, Fe and vitamin status (A, B6, C) were assessed in 126 Dutch boys aged 10-11 years (response 71%). Body mass index (BMI) and the sum of four skinfolds were strongly associated (r 0.85, P < 0.01) and 8% of...article 1991
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Medisch Biologisch Laboratorium TNO (author), Mol, M.A.E. (author), Nanninga, P.B. (author), van Eendenburg, J.P. (author), Westerhof, W. (author), Mekkes, J.R. (author), van Ginkel, C.J.W. (author)Skin equivalents that consisted of a noncontracted collagen gel populated with allogeneic fibroblasts and covered with autologous cultured keratinocytes were used for grafting venous leg ulcers. The results were compared in the same patient with those obtained with a routinely used standard method of grafting with autologous full-thickness punch...article 1991
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- Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author), Frencken, J.E. (author), Truin, G.J. (author), van't Hof, M.A. (author), König, K.G. (author), Kahabuka, F.K. (author), Mulder, J. (author), Kalsbeek, H. (author) article 1991
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Verrips, G.H. (author), Frencken, J.E. (author), Kalsbeek, H. (author), ter Horst, G. (author), Filedt Kok-Weimar, T.L. (author), TNO Preventie en Gezondheid (author)The aim of this study was threefold: first, to assess the oral health of Turkish, Moroccan, Surinamese, Dutch and "other" 5-yr-old children living in Amsterdam; second, to identify risk indicators for caries, in addition to ethnicity; and third, to identify potential risk factors related to differences in caries experience in these children....article 1992
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van Loon, A.A.W.M. (author), Timmerman, A.J. (author), van der Schans, G.P. (author), Lohman, P.H.M. (author), Baan, R.A. (author), Medisch Biologisch Laboratorium TNO (author)Exposure of cells to ionizing radiation gives rise to DNA damage, comprising strand breaks and base modifications. All these lesions may contribute to cell death, mutagenesis and/or carcinogenesis, but their relative contributions are likely to be different. It is important, therefore, to study the various damages with respect to their abundance...article 1992
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Havenith, G. (author), van de Linde, E.J.G. (author), Heus, R. (author)Hand cooling and resulting comfort and pain were studied in 12 subjects, while touching six different materials (polyurethane foam, wood, nylon, rustproof steel, aluminium, and temperature-controlled metal) which were initially at ambient temperature. This was done for three ambient temperatures (-10°, 0° and 10°C), after pre-exposure exercise...article 1992
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Geuskens, R.B.M. (author), van der Klaauw, M.M. (author), van der Tuin, J. (author), van Hemmen, J.J. (author), Medisch Biologisch Laboratorium TNO (author)A study of the health hazards for workers exposed to styrene in the Dutch glass-reinforced plastics industry was undertaken. The open mould techniques of filament winding, spraying and hand laminating were chosen for study because exposure of workers using them was expected to be high. Occupational hygiene surveys were conducted in four plants....article 1992
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