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Wortel, E. (author), de Geus, G.H. (author), Kok, G. (author), TNO Preventie en Gezondheid (author)Home-related injuries are a major threat to pre-school children in the western world. In this study the behavioral determinants of 18 parental safety measures were assessed. To select behavioral determinants, the Attitude-Social influence-Self-efficacy/barriers model was used with the inclusion of variables from the Health Belief Model and the...article 1995
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Jonker, D. (author), Til, H.P. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)To compare the possible effects of microwave and conventional cooking on a range of common dietary components, mixed human diets containing beef, potatoes and vegetables were fed to groups of 10 male and 10 female Wistar rats for 13 wk. The diet ingredients were cooked by either of the methods in a normal and an abused manner, the latter...article 1995
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Nijhoff, W.A. (author), Grubben, M.J.A.L. (author), Nagengast, F.M. (author), Jansen, J.B.M.J. (author), Verhagen, H. (author), van Poppel, G. (author), Peters, W.H.M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)A high intake of glucosinolate-containing cruciferous vegetables, such as Brussels sprouts (Brassica oleraceae), has been linked to a decreased cancer risk, but the underlying mechanism is still unclear. The aim of this study was to reveal possible modulating effects of consumption of Brussels sprouts on duodenal, rectal and lymphocytic (i)...article 1995
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Hirasing, R.A. (author), TNO Preventie en Gezondheid (author)Objective: To determine if the incidence of insulin-dependent diabetes mellitus (IDDM) in the age group of 0-19 years in the Netherlands in the period 1988-1990 had changed in comparison with the period 10 years before. Design: Retrospective. Setting: The Netherlands. Method: In 1991 a questionnaire was sent to all paediatricians and internists...article 1995
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Hirasing, R.A. (author), Aardoom, H.A. (author), van den Heuvel, E.W. (author), Sanavro, F.L. (author), Leeuwenburg, J. (author), TNO Preventie en Gezondheid (author)Objective. To establish the prevalence of chronic diseases reported by parents among a random population of Dutch children. Furthermore, to establish how often these children visited a physician because of a chronic disease, and used drugs for its treatment. Setting. Dordrecht and environs. Design. Descriptive. Method. In the school year 1990...article 1995
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Kardinaal, A.F.M. (author), van 't Veer, P. (author), Brants, H.A.M. (author), van den Berg, H. (author), van Schoonhoven, J. (author), Hermus, R.J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)For an evaluation of fat-soluble vitamin concentrations in adipose tissue as biomarkers of intake, estimates of usual intake of β-carotene, total vitamin A, and vitamin E (assessed by food frequency questionnaire) were compared with plasma and adipose tissue concentrations of β-carotene, retinol, and α-tocopherol, respectively. Data were...article 1995
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Hennis, B.C. (author), van Boheemen, P.A. (author), Koeleman, B.P.C. (author), Boomsma, D.I. (author), Engesser, L. (author), van Wees, A.G.M. (author), Novakova, I. (author), Brommer, E.J.P. (author), Kluft, C. (author), Gaubius Instituut TNO (author)Recent studies describe families with both elevated plasma HRG levels and thrombosis. In order to study the possibility that allelic variants of the HRG locus are associated with differences in HRG level, we studied linkage between HRG levels and a dinucleotide repeat polymorphism in a Dutch family which was selected on the presence of both...article 1995
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Gevers Leuven, J.A. (author), Gaubius Laboratory TNO Preventie en Gezondheid (author)Lipoprotein metabolism is involved in atherogenesis. Female sex-hormones have substantial effects on both lipoprotein metabolism and the vessel wall. Cholesterol, one of the major lipids in lipoproteins, is both the substrate for, and the target of, the steroidal sex hormones.article 1994
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Verloove-Vanhorick, S.P. (author), Veen, S. (author), Ens-Dokkum, M.H. (author), Schreuder, A.M. (author), Brand, R. (author), Ruys, J.H. (author), TNO Preventie en Gezondheid (author)Objective. The objective of this study was to examine the relationship between sex and disabilities or handicaps at 5 years of age in infants born at less than 32 weeks gestation. Design. From the nationwide collaborative survey starting in 1983, including perinatal data obtained during routine perinatal care and follow-up assessments by the...article 1994
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Ganesh, S. (author), Sier, C.F.M. (author), Griffioen, G. (author), Vloedgraven, H.J.M. (author), de Boer, A. (author), Welvaart, K. (author), van de Velde, C.J.H. (author), van Krieken, J.H.J.M. (author), Verheijen, J.H. (author), Lamers, C.B.H.W. (author), Verspaget, H.W. (author), Instituut voor Verouderings- en Vaatziekten Onderzoek TNO (author)Human colorectal carcinogenesis has been shown previously to be associated with impressive changes in the tissue levels of plasminogen activators and their inhibitors, exemplified by an increase in the urokinase-type plasminogen activator (u-PA) and the inhibitors PAI-1 and PAI-2, and a decrease in tissue-type plasminogen activator (t-PA). In...article 1994
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- Hirasing, R.A. (author), TNO Preventie en Gezondheid (author) article 1994
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Kampman, E. (author), Bijl, A.J. (author), Kok, C. (author), van 't Veer, P. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)We analysed data from a case-control study in the Netherlands in order to investigate whether reproductive events and hormonal factors are similarly related to colon cancer risk in men and women after adjustment for dietary factors. In total, 232 colon cancer cases (102 women, 130 men) and 259 controls (123 women, 136 men) were interviewed about...article 1994
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Goldbohm, R.A. (author), van den Brandt, P.A. (author), van 't Veer, P. (author), Dorant, E. (author), Sturmans, F. (author), Hermus, R.J.J. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)The association between alcohol consumption and cancer of the colon and rectum was investigated in a prospective cohort study, conducted in the Netherlands from 1986 onwards among 120,852 men and women, aged 55 to 69 years. During 3.3 years of follow-up, 312 and 166 cases of colon and rectal cancer had accumulated, respectively. After exclusion...article 1994
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Hirasing, R.A. (author), Gena, S.A.D. (author), Simon, J.G. (author), Kossen-Boot, H. (author), Meulmeester, J.F. (author), van den Oudenrijn, C. (author), TNO Preventie en Gezondheid (author)Objective. To determine the exposure to cigarette smoke of infants aged 0-14 months. Design. Cross-sectional. Setting. The area of Westfriesland, the Netherlands. Method. All parents of infants 8 days, 3, 5, 9, and 14 months old who visited the infant welfare centre in 1992 were asked to fill in a questionnaire. Results. The questionnaire was...article 1994
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Ruwaard, D. (author), Hirasing, R.A. (author), Reeser, H.M. (author), van Buuren, S. (author), Barker, K. (author), Heine, R.J. (author), Geerdink, R.A. (author), Bruining, G.J. (author), Vaandrager, G.J. (author), Verloove-Vanhorick, S.P. (author), TNO Preventie en Gezondheid (author)OBJECTIVE - A nationwide retrospective study was conducted to assess the incidence of type 1 diabetes in The Netherlands among children <20 years of age in 1988-1990. The first study with a similar design covered 1978-1980. RESEARCH DESIGN AND METHODS - The capture-recapture census method was chosen for analysis of the data. A questionnaire was...article 1994
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Reerink, J.D. (author), Herngreen, W.P. (author), Meulmeester, J.F. (author), den Ouden, A.L. (author), Verloove-Vanhorick, S.P. (author), Ruys, J.H. (author), TNO Preventie en Gezondheid (author)Objective. To assess consumption of medical care for infants and toddlers provided by general practitioners and specialists, and of hospital admissions for young children. Design. Descriptive. Setting. Dutch Child Health Clinics (CHC). Method. An aselect cohort of newborns of 1988/89 of the Social Medical Survey of children attending Child...article 1994
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Hille, E.T.M. (author), den Ouden, A.L. (author), Bauer, L. (author), van den Oudenrijn, C. (author), Brand, R. (author), Verloove-Vanhorick, S.P. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)To assess the impact of both perinatal disorders and developmental problems identified at preschool age on school performance, we followed a virtually complete birth cohort of very premature (<32 completed weeks of gestation) and very low birth weight infants until they were 9 years of age. In 84% of the survivors (n = 813), data on school...article 1994
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Hirasing, R.A. (author), Reus, H. (author), TNO Preventie en Gezondheid (author)Good long-term results of dry bed training of children with nocturnal enuresis. Objective. To determine the long-term effect of dry bed training in a youth health care setting. Setting. Haarlemmermeer, the Netherlands.Design. Descriptive. Method. Parents of 36 children (mean age 9 year) subjected to dry bed training in 1987-1989, were asked in...article 1994
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van de Kar, N.C.A.J. (author), van Hinsbergh, V.W.M. (author), Brommer, E.J.P. (author), Monnens, L.A.H. (author), Gaubius Laboratory TNO Preventie en Gezondheid Instituut voor verouderings- en vaatziekten onderzoek TNO (author)Fibrinolytic parameters and von Willebrand factor (vWF) antigen were measured in the plasma of 10 patients with hemolytic uremic syndrome (HUS). Samples were taken at presentation and again 2 wk later, before and after infusion of 1-desamino-8-arginine vasopressin. Compared with the plasma values of healthy control children, levels of tissue...article 1994
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de Knijff, P. (author), van den Maagdenberg, A.M.J.M. (author), Frants, R.R. (author), Havekes, L.M. (author), TNO Preventie en Gezondheid (author)Apolipoprotein E (apoE) is one of the major protein constituents of chylomicron and very-low-density lipoprotein (VLDL) remnants and plays a central role as a ligand in the receptor-mediated uptake of these particles by the liver. Including the most common variant, apoE3, 30 apoE variants have been characterized. At present, 14 apoE variants...article 1994
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