document

A review of the data quality and comparability of case-control studies of low-level exposure to benzene in the petroleum industry

Miller, B.G. (author), Fransman, W. (author), Heederik, D. (author), Hurley, J.F. (author), Kromhout, H. (author), Fitzsimons, E. (author), TNO Kwaliteit van Leven (author)

Purpose Published case–control studies of risks of leukaemia following low exposures to benzene in the distribution of petroleum (gasoline) have not all identiWed the same level of risk, but the studies have had diVerences in cohort inclusion, case determination and availability of occupational and lifestyle data. We reviewed the quality and...

article 2010

document

Stoffenmanager: een web-based control banding tool

Verbist, K., (author), Marquart, H., (author), Heussen, H., (author), Schinkel, J., (author), West, J., (author), Fransman, W., (author), van Niftrik, M, (author), Tielemans, E. (author)

article 2011

document

Comparison of two expert-based assessments of diesel exhaust exposure in a case-control study: Programmable decision rules versus expert review of individual jobs

Pronk, A. (author), Stewart, P.A. (author), Coble, J.B. (author), Katki, H.A. (author), Wheeler, D.C. (author), Colt, J.S. (author), Baris, D. (author), Schwenn, M. (author), Karagas, M.R. (author), Johnson, A. (author), Waddell, R. (author), Verrill, C. (author), Cherala, S. (author), Silverman, D.T. (author), Friesen, M.C. (author)

Objectives: Professional judgment is necessary to assess occupational exposure in population-based case-control studies; however, the assessments lack transparency and are time-consuming to perform. To improve transparency and efficiency, we systematically applied decision rules to questionnaire responses to assess diesel exhaust exposure in the...

article 2012

document

Determinants of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans in house dust samples from four areas of the United States

Deziel, N.C. (author), Nuckols, J.R. (author), Colt, J.S. (author), de Roos, A.J. (author), Pronk, A. (author), Gourley, C. (author), Severson, R.K. (author), Cozen, W. (author), Cerhan, J.R. (author), Hartge, P. (author), Ward, M.H. (author)

Determinants of levels of polychlorinated dibenzo- p-dioxins and polychlorinated dibenzofurans (PCDD/F) in dust in U.S. homes are not well characterized. We conducted a pilot study to evaluate the relationship between concentrations of PCDD/F in house dust and residential proximity to known sources, including industrial facilities and traffic....

article 2012

document

A roadmap towards a globally harmonized approach for occupational health surveillance and epidemiology in nanomaterial workers

Riediker, M. (author), Schubauer-Berigan, M.K. (author), Brouwer, D.H. (author), Nelissen, I. (author), Koppen, G. (author), Frijns, E. (author), Clark, K.A. (author), Hoeck, J. (author), Liou, S.H. (author), Ho, S.F. (author), Bergamaschi, E. (author), Gibson, R. (author)

Objective: Few epidemiological studies have addressed the health of workers exposed to novel manufactured nanomaterials. The small current workforces will necessitate pooling international cohorts. Method: A roadmap was defined for a globally harmonized framework for the careful choice of materials, exposure characterisation, identification of...

article 2012

document

Inside the black box: Starting to uncover the underlying decision rules used in a one-by-one expert assessment of occupational exposure in case-control studies

Wheeler, D.C. (author), Burstyn, I. (author), Vermeulen, R. (author), Yu, K. (author), Shortreed, S.M. (author), Pronk, A. (author), Stewart, P.A. (author), Colt, J.S. (author), Baris, D. (author), Karagas, M.R. (author), Schwenn, M. (author), Johnson, A. (author), Silverman, D.T. (author), Friesen, M.C. (author)

Objectives Evaluating occupational exposures in population-based case-control studies often requires exposure assessors to review each study participant's reported occupational information job-by-job to derive exposure estimates. Although such assessments likely have underlying decision rules, they usually lack transparency, are time consuming...

article 2013

document

Skin symptoms in bakery and auto body shop workers: Associations with exposure and respiratory symptoms

Arrandale, V. (author), Meijster, T. (author), Pronk, A. (author), Doekes, G. (author), Redlich, C.A. (author), Holness, D.L. (author), Heederik, D. (author)

Purpose: Despite the importance of skin exposure, studies of skin symptoms in relation to exposure and respiratory symptoms are rare. The goals of this study were to describe exposure-response relationships for skin symptoms, and to investigate associations between skin and respiratory symptoms in bakery and auto body shop workers. Methods: Data...

article 2013

document

Workplace air measurements and likelihood of exposure to manufactured nano-objects, agglomerates, and aggregates

Brouwer, D.H. (author), van Duuren-Stuurman, B. (author), Berges, M. (author), Bard, D. (author), Jankowska, E. (author), Moehlmann, C. (author), Pelzer, J. (author), Mark, D. (author)

Manufactured nano-objects, agglomerates, and aggregates (NOAA) may have adverse effect on human health, but little is known about occupational risks since actual estimates of exposure are lacking. In a large-scale workplace air-monitoring campaign, 19 enterprises were visited and 120 potential exposure scenarios were measured. A multi-metric...

article 2013

document

Workplace air measurements and likelihood of exposure to manufactured nano-objects, agglomerates, and aggregates

Brouwer, D.H. (author), van Duuren-Stuurman, B. (author), Berges, M. (author), Bard, D. (author), Jankowska, E. (author), Moehlmann, C. (author), Pelzer, J. (author), Mark, D. (author)

article 2013

document

Comparison of algorithm-based estimates of occupational diesel exhaust exposure to those of multiple independent raters in a population-based case-control study

Friesen, M.C. (author), Pronk, A. (author), Wheeler, D.C. (author), Chen, Y.-C. (author), Locke, S.J. (author), Zaebst, D.D. (author), Schwenn, M. (author), Johnson, A. (author), Waddell, R. (author), Baris, D. (author), Colt, J.S. (author), Silverman, D.T. (author), Stewart, P.A. (author), Katki, H.A. (author)

Objectives: Algorithm-based exposure assessments based on patterns in questionnaire responses and professional judgment can readily apply transparent exposure decision rules to thousands of jobs quickly. However, we need to better understand how algorithms compare to a one-by-one job review by an exposure assessor. We compared algorithm-based...

article 2013

document

Organizing sustainable partnerships between employment agencies and hiring companies: The Dutch case

Goudswaard, A. (author), de Leede, J. (author)

bookPart 2014

document

Exhaled nitric oxide in spray painters exposed to isocyanates: Effect modification by atopy and smoking

Jonaid, B.S. (author), Pronk, A. (author), Doekes, G. (author), Heederik, D. (author)

Background: Isocyanate asthma is one of the most frequently identified forms of occupational asthma in industrialised countries. The underlying mechanisms have not been clarified. There is only limited information about the relationship between exhaled nitric oxide (eNO) and occupational exposure to isocyanates and asthma. Objectives: To...

article 2014

document

Stoffenmanager 2.0: Een preview

le Feber, M. (author)

article 2014

document

Towards a comprehensive research design for studying integrated care

Dessers, E. (author), Vrijhoef, H.J.M. (author), Annemans, L. (author), Cambré, B. (author), Dhondt, S. (author), Hellings, J. (author), Hermans, K. (author), Kenis, P. (author), Nys, H. (author), Vandijck, D. (author), van Hootegem, G. (author)

Given that integrated care includes many different aspects, this paper seeks to design a comprehensive research approach and explains how this approach is applied in the CORTEXS research project on integrated care in the Flemish Community in Belgium. A systemic view on integrated care is translated into a multi-level, multi-disciplinary, multi...

article 2014

document

Advanced REACH tool: A Bayesian model for occupational exposure assessment

McNally, K. (author), Warren, N. (author), Fransman, W. (author), Entink, R.K. (author), Schinkel, J. (author), Van Tongeren, M. (author), Cherrie, J.W. (author), Kromhout, H. (author), Schneider, T. (author), Tielemans, E. (author)

This paper describes a Bayesian model for the assessment of inhalation exposures in an occupational setting; the methodology underpins a freely available web-based application for exposure assessment, the Advanced REACH Tool (ART). The ART is a higher tier exposure tool that combines disparate sources of information within a Bayesian statistical...

article 2014

document

Vragenlijst Werkgevers Enquête Arbeid 2014

De Werkgevers Enquête Arbeid (WEA) is een regelmatig terugkerend vragenlijstonderzoek onder bedrijven en instellingen. Het onderzoek wordt uitgevoerd door TNO in overleg met het Ministerie van Sociale Zaken en Werkgelegenheid, en Panteia BV.

other 2014

document

Field and Laboratory Measurements Related to Occupational and Consumer Exposures

Brouwer, D.H. (author), Kuijpers, E. (author), Bekker, C. (author), Asbach, C. (author), Kuhlbusch, T.A.J. (author)

bookPart 2014

document

Zijn antimicrobiële coatings veilig? Nanocentre zoekt het uit

Kuijpers, E. (author), le Feber, M. (author)

article 2014

document

Investing in workplace innovation pays off for SME's: A regional innovation initiative from the Netherlands

Oeij, P.R.A. (author), de Vroome, E.M.M. (author), Bolland, A. (author), Gründemann, R.W.M. (author), van Teeffelen, L. (author)

From 2009 to 2013 the workplace innovation project “My Enterprise 2.0” was carried out in the region of Utrecht in the Netherlands in order to strengthen the workplace innovation capability of small and medium-sized enterprises (SMEs). Participating enterprises completed a questionnaire regarding the “workplace innovativeness” of their company....

article 2014

document

Zitten is dodelijk!? Feit of fictie? Noodzaak en mogelijkheden voor preventie

Douwes, M. (author), Hendriksen, I. (author)

public lecture 2014