(1 - 20 of 22)

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Hendriks, H. (author), van de Rest, O. (author), Snippe, A. (author), Kieboom, J. (author), Hogenelst, K. (author)
Long-term alcohol abuse is associated with poorer cognitive performance. However, the associations between light and moderate drinking and cognitive performance are less clear. We assessed this association via cross-sectional and longitudinal analyses in a sample of 702 Dutch students. At baseline, alcohol consumption was assessed using...
article 2020
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Schrieks, I.C. (author), Heil, A.L. (author), Hendriks, H.F. (author), Mukamal, K.J. (author), Beulens, J.W. (author)
OBJECTIVE: Moderate alcohol consumption is associated with a reduced risk of type 2 diabetes. This reduced risk might be explained by improved insulin sensitivity or improved glycemic status, but results of intervention studies on this relation are inconsistent. The purpose of this study was to conduct a systematic review and meta-analysis of...
article 2015
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van Avesaat, M. (author), Troost, F.J. (author), Ripken, D. (author), Hendriks, H.F. (author), Aam, M. (author)
BACKGROUND: Activation of the ileal brake, by infusing lipid directly into the distal part of the small intestine, alters gastrointestinal (GI) motility and inhibits food intake. The ileal brake effect on eating behavior of the other macronutrients is currently unknown. OBJECTIVE: The objective of this study was to investigate the effects of...
article 2015
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van Avesaat, M. (author), Troost, F.J. (author), Ripken, D. (author), Peters, J. (author), Hendriks, H.F.J. (author), Masclee, A.A.M. (author)
Background: Taste receptors are expressed not only in taste buds but also in the gastrointestinal tract. It has been hypothesized that these receptors may play a role in satiety and food intake. Objective: This study investigated the effect of intraduodenal tastant infusions (bitter, sweet, and umami) on food intake, hunger and fullness,...
article 2015
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Joosten, M.M. (author), Schrieks, I.C. (author), Hendriks, H.F.J. (author)
Background: Fetuin-A, a liver-derived glycoprotein that impairs insulin-signalling, has emerged as a biomarker for diabetes risk. Although moderate alcohol consumption has been inversely associated with fetuin-A, data from clinical trials are lacking. Thus, we evaluated whether moderate alcohol consumption decreases circulating levels of fetuin...
article 2014
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Bakker, G.C.M. (author), van Erk, M.J. (author), Pellis, L. (author), Wopereis, S. (author), Rubingh, C.M. (author), Cnubben, N.H.P. (author), Kooistra, T. (author), van Ommen, B. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Background: Low-grade chronic inflammation in overweight subjects is thought to play an important role in disease development. Objective: It was hypothesized that specific dietary components are able to reduce low-grade inflammation as well as metabolic and oxidative stress. Design: Dietary products [resveratrol, green tea extract, α-tocopherol,...
article 2010
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Beulens, J.W.J. (author), Rimm, E.B. (author), Hendriks, H.F.J. (author), Hu, F.B. (author), Manson, J.E. (author), Hunter, D.J. (author), Mukamal, K.J. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE - We sought to investigate whether a polymorphism in the alcohol dehydrogenase 1c (ADH1C) gene modifies the association between alcohol consumption and type 2 diabetes. RESEARCH DESIGN AND METHODS - In nested case-control studies of 640 women with incident diabetes and 1,000 control subjects from the Nurses' Health Study and 383 men...
article 2007
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Hendriks, M.M.W.B. (author), Smit, S. (author), Akkermans, W.L.M.W. (author), Reijmers, T.H. (author), Eilers, P.H.C. (author), Hoefsloot, H.C.J. (author), Rubingh, C.M. (author), de Koster, C.G. (author), Aerts, J.M. (author), Smilde, A.K. (author), TNO Kwaliteit van Leven (author)
SELDI-TOF-MS is rapidly gaining popularity as a screening tool for clinical applications of proteomics. Application of adequate statistical techniques in all the stages from measurement to information is obligatory. One of the statistical methods often used in proteomics is classification: the assignment of subjects to discrete categories, for...
article 2007
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Beulens, J.W.J. (author), van Loon, L.J.C. (author), Kok, F.J. (author), Pelsers, M. (author), Bobbert, T. (author), Spranger, J. (author), Helander, A. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Aims/hypothesis: The aim of this study was to investigate whether moderate alcohol consumption increases plasma high molecular weight (HMW) adiponectin and/or muscle oxidative capacity. Materials and methods: Eleven lean (BMI 18-25 kg/m2) and eight overweight (BMI ≥27 kg/m2) men consumed 100 ml whisky (∼32 g alcohol) or water daily for 4 weeks...
article 2007
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Koppes, L.L.J. (author), Dekker, J.M. (author), Hendriks, H.F.J. (author), Bouter, L.M. (author), Heine, R.J. (author), TNO Kwaliteit van Leven (author)
Aims/hypothesis: This systematic review examines the relationship between alcohol consumption and long-term complications of type 2 diabetes. Meta-analyses could only be performed for total mortality, mortality from CHD, and CHD incidence, because the availability of articles on other complications was too limited. Materials and methods: A...
article 2006
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van den Elzen, A.P. (author), Sierksma, A. (author), Oren, A. (author), Vos, L.E. (author), Witteman, J.C. (author), Grobbee, D.E. (author), Hendriks, H.F. (author), Uiterwaal, C.S. (author), Bots, M.L. (author), TNO Kwaliteit van Leven (author)
Background: Moderate alcohol consumption has been shown to protect against cardiovascular disease. Aortic stiffness can be regarded as a marker of cardiovascular disease risk. Previously we have shown an inverse to J-shaped association between alcohol intake and aortic stiffness in middle-aged and elderly men and postmenopausal women. Objective:...
article 2005
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Beulens, J.W.J. (author), Sierksma, A. (author), Schaafsma, G. (author), Kok, F.J. (author), Struys, E.A. (author), Jakobs, C. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Background: Moderate alcohol consumption is associated with a decreased risk of cardiovascular disease. Because plasma homocysteine (tHcy) is considered an independent risk factor for cardiovascular disease and associated with alcohol consumption, the authors investigated the effect of moderate alcohol consumption on kinetics of plasma tHcy...
article 2005
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Sierksma, A. (author), Sarkola, T. (author), Eriksson, C.J.P. (author), van der Gaag, M.S. (author), Grobbee, D.E. (author), Hendriks, H.F.J. (author), TNO Voeding (author)
Background: Moderate alcohol consumption is inversely associated with cardiovascular diseases. Changes in hormone levels might in part help explain the positive health effect. This study was performed to examine the effect of moderate alcohol consumption on plasma dehydroepiandrosterone sulfate (DHEAS), testosterone, and estradiol levels....
article 2004
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van Herpen-Broekmans, W. (author), Klöpping-Ketelaars, I. (author), Michiel, B. (author), Cornelis, K. (author), Hans, P. (author), Hendriks, F.J. (author), Tijburg, L. (author), van Poppel, G. (author), Kardinaal, A. (author), TNO Preventie en Gezondheid (author)
Background: Endothelial cell dysfunction may be related to an increase in cellular oxidative stress. Carotenoids and vitamins could have an antioxidant-mediated tempering influence on endothelial function and inflammation, thereby reducing the risk of atherosclerosis. Methods: We measured serum carotenoids, α-tocopherol and Vitamin C...
article 2004
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Boelsma, E. (author), Lamers, R.-J.A.N. (author), Hendriks, H.F.J. (author), van Nesselrooij, J.H.J. (author), Roza, L. (author), TNO Voeding (author)
Ginkgo biloba extract has been advocated for the improvement of blood circulation in circulatory disorders. This study investigated the effect of the Gingko biloba extract EGb 761 on skin blood flow in healthy volunteers and accompanying changes in urinary metabolites. Twenty-seven healthy middle-aged subjects participated in a randomized,...
article 2004
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Hendriks, H.F.J. (author), Brink, E.J. (author), Meijer, G.W. (author), Princen, H.M.G. (author), Ntanios, F.Y. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective: To evaluate both efficacy and safety in humans of long-term consumption of spreads containing plant sterol esters. Design: Randomized double-blind placebo-controlled parallel trial. Subjects: Hundred and eighty-five healthy volunteers (35-64y). Intervention: Volunteers daily consumed 20g spread enriched with 1.6g plant sterols as...
article 2003
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Sierksma, A. (author), van der Gaag, M.S. (author), Kluft, C. (author), Hendriks, H.F.J. (author), TNO Voeding (author)
Objective: To evaluate the effect of moderate alcohol consumption on the acute phase proteins C-reactive protein and fibrinogen. Design: Randomized, diet-controlled, cross-over study. Setting: The study was performed at TNO Nutrition and Food Research, Zeist, The Netherlands. Subjects: Ten middle-aged men and 10 postmenopausal women, all...
article 2002
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Sierksma, A. (author), van der Gaag, M.S. (author), van Tol, A. (author), James, R.W. (author), Hendriks, H.F.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Background: The inverse association between moderate drinking and coronary heart disease mortality is well established. This study was performed to investigate the kinetics of the alcohol-induced increases in apo A-1, HDL cholesterol, and paraoxonase (PON) activity, as well as to study whether the alcohol-induced increases in PON activity differ...
article 2002
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van Puymbroeck, M. (author), Kuilman, M.E.M. (author), Maas, R.F.M. (author), Witkamp, R.F. (author), Leyssens, L. (author), van Miert, A.S.J.P.A.M. (author), Hendriks, L. (author), van der Zande, D.J.M. (author), Adriaensens, P. (author), Jacobs, M.-P. (author), Raus, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The metabolism of the illegal growth promoter ethylestrenol (EES) was evaluated in bovine liver cells and subcellular fractions of bovine liver preparations. Incubations with bovine microsomal preparations revealed that EES is extensively biotransformed into norethandrolone (NE), another illegal growth promoter. Furthermore, incubations of...
article 1999
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Hendriks, H.F.J. (author), Weststrate, J.A. (author), van Vliet, T. (author), Meijer, G.W. (author)
Objective: To investigate the dose-response relationship between cholesterol lowering and three different, relatively low intake levels of plant sterols (0.83, 1.61, 3.24 g/d) from spreads. To investigate the effects on lipid-soluble (pro)vitamins. Design: A randomized double-blind placebo controlled balanced incomplete Latin square design using...
article 1999
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