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Bleiker, M.A. (author), Styblo, K. (author), Gezondheidsorganisatie TNO (author)
If the trend in risk of tuberculosis infection is estimated from the 1967-1976 data alone (which contain only 6 usable annual figures), the estimate is a decrease of 9.3% annually, a figure substantially lower than the estimate from the 1956-1966 data alone, viz. 13.7%. It is as yet impossible to decide whether or not this represents a real...
article 1978
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van Dokkum, W. (author), de Vos, R.H. (author), Cloughley, F.A. (author), Hulshof, K.F.A.M. (author), Dukel, F. (author), Wijsman, J.A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
During a period of 2 years, every 2 months 126 different food items forming a 'market basket' were purchased, prepared and divided into twelve food commodity groups. The 'market basket' was based on a study of the dietary pattern of 16- to 18-year-old male adolescents. In the (homogenized) food group various additives and components of...
article 1982
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Kroes, R. (author), Instituut CIVO-Toxicologie en voeding TNO (author)
Short-term tests designed to detect possible carcinogenicity have been extensively refined during the last years. Presently, many more or less simple and convenient systems are available to detect mutations, chromosome effects, DNA damage, and malignant transformation. Although their relevance to carcinogenicity is often reasonably good,...
article 1983
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de Vos, R.H. (author), van Dokkum, W. (author), Olthof, P.D.A. (author), Quirijns, J.K. (author), Muys, T. (author), van der Poll, J.M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Over a period of 2 yr 126 different food items of a market basket of 16-18 yr old males were purchased every 2 months. The foodstuffs were prepared as for eating, and were combined in 12 commodity groups. Twelves samples of each food group were homogenized and analysed for 78 different chemicals, including pesticides, PCBs, bromine, heavy metals...
article 1984
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Vaandrager, G.J. (author), Bruining, G.J. (author), Veenhof, F.J. (author), Drayer, N.M. (author), TNO Preventie en Gezondheid (author)
The incidence of childhood diabetes (0-19 years of age) in The Netherlands, where there is no nationalized health-care system, was investigated retrospectively in the years 1978 to 1980 inclusive. The method chosen was a questionnaire among all Dutch paediatricians and internal physicians acting as consultants. Ascertainment was by the same...
article 1984
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Guicherit, R. (author), Schulting, F.L. (author), Instituut voor Milieuhygiëne en Gezondheidstechniek TNO (author)
In this paper concentration levels of various classes of organic chemicals in The Netherlands are reported for the base year 1980. From these levels the average intake of the Dutch population by inhalation was calculated to be ~1.5 g year-1. This gives reason for concern because many of the compounds either seem to exhibit carcinogenic...
article 1985
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van den Berg, H. (author), Louwerse, E.S. (author), Bruinse, H.W. (author), Thissen, J.T.N.M. (author), Schrijver, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The vitamin B6 status of women suffering from premenstrual symptoms (PMS, n = 19) and a group of matched controls (n = 19) has been investigated. The women volunteering in the study were selected on strictly defined criteria. Several biochemical parameters of the metabolism of vitamin B6 and tryptophan were studied in blood and urine samples...
article 1986
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van Dokkum, W. (author), de Vos, R.H. (author), Muys, Th. (author), Wesstra, J.A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
1. During a period of 2.5 years, every 3 months 221 different food items forming a 'market basket' were purchased, prepared and divided into twenty-three food-commodity groups. The 'market basket' was based on a study of the dietary intake of 18-year-old male, Dutch adolescents. In the (homogenized) food groups various minerals and trace...
article 1989
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van 't Veer, P. (author), Dekker, J.M. (author), Lamers, J.W.J. (author), Kok, F.J. (author), Schouten, E.G. (author), Brants, H.A.M. (author), Sturmans, F. (author), Hermus, R.J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
In a case-control study in The Netherlands, we observed a significantly lower consumption of fermented milk products (predominantly yogurt and buttermilk) among 133 incident breast cancer cases as compared to 289 population controls (mean ± SD among users only, 116 ± 100 versus 157 ± 144 g/day; P<0.01). The age-adjusted odds ratio of daily...
article 1989
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van Beekum, T. (author), Banta, H.D. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
Limited resources for health care and increasing health care costs have led to proposals to expand home care services. Presently, home care technology is rather primitive. Its development and use have been largely unplanned. Nonetheless, home care technology is growing in response to obvious needs, and a number of experiments in the Netherlands...
article 1989
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van Poppel, G. (author), Schrijver, J. (author), Meulmeester, J.F. (author), Kempen-Voogd, N. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Chemicals/CAS: Cholesterol, 57-88-5; Iron, 7439-89-6; Vitamins
article 1989
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Engesser, L. (author), Brommer, E.J.P. (author), Kluft, C. (author), Briet, E. (author), Gaubius Instituut TNO (author)
Two hundred and three patients with venous thrombophilia were investigated in order to find out whether an elevated plasma concentration of plasminogen activator inhibitor (PAI) could be a cause of their tendency to thrombosis. The patients were studied in an asymptomatic period about 3 months after their last thromboembolic episode. PAI...
article 1989
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de Kort, W.L.A.M. (author), Medisch Biologisch Laboratorium TNO (author)
In dit artikel wordt een overzicht gegeven van de doelstellingen en de praktijk t.a.v. aanstellingskeurigen in Nederland. Ingegaan wordt op : de situatie in Nederland in de praktijk (300000 à 350000 aanstellingskeuringen per jaar met een afkeuringspercentage van 2) ; medische geschiktheid als selectie - criterium ; en de kwaliteit van de...
article 1990
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Lowik, M.R.H. (author), Schrijver, J. (author), Odink, J. (author), van den Berg, H. (author), Wedel, M. (author), Hermus, R.J.J. (author), TNO Kwaliteit van Leven (author)
In a nationwide survey the nutritional status was assessed of 539 apparently healthy, independently living elderly aged 65-79 years. Anthropometric data showed no energy deficits. The prevalence of anemia was 4 and 1% among men and women, respectively. Many elderly showed a low level of 25-hydroxyvitamin D in plasma (< 31 nmol/L: men 35%; women...
article 1990
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Kalsbeek, H. (author), Verrips, G.H. (author), TNO Preventie en Gezondheid (author)
Data in a WHO report relating caries prevalence and the use of fluorides in different European countries were compared with data obtained directly from investigators in the field of oral epidemiology. The reliability of DMFT indices of 12-year-old children, mentioned in the WHO report, appeared sufficient to make comparisons between countries on...
article 1990
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van 't Veer, P. (author), van der Wielen, R.P.J. (author), Kok, F.J. (author), Hermus, R.J.J. (author), Sturmans, F. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The association between breast cancer and selenium, measured in the diet, plasma, erythrocytes, and toenails, was investigated in a case-control study in the Netherlands during 1985-1987. Dietary selenium intake was assessed by a structured dietary history technique among 133 breast cancer cases and 238 population controls. Absolute and energy...
article 1990
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Meulmeester, J.F. (author), van der Berg, H. (author), Wedel, M. (author), Boshuis, P.G. (author), Hulshof, K.F.A. (author), Luyken, R. (author), TNO Preventie en Gezondheid Centraal Instituut voor Voedingsonderzoek TNO (author)
At the end of the winter circulating concentrations of 25-hydroxyvitamin D (25-OHD) in Asian and Mediterranen immigrants in northwestern European countries are usually very low. This may lead to vitamin D deficiency and eventually to rickets. Children are more prone to develop vitamin D deficiency. The vitamin D status of 8-year-old Turkish,...
article 1990
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Frencken, J.E. (author), Kalsbeek, H. (author), Verrips, G.H. (author), TNO Preventie en Gezondheid (author)
In 1973, 1976, 1979, 1982 and 1988 caries investigations were carried out amongst 6- and 12-year-old primary schoolchildren to study the effectiveness of a dental health campaign begun in 1973. This campaign and the school dental health services were stopped in 1985. In all the years, except 1988, radiographs formed part of the caries...
article 1990
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de Vos, R.H. (author), van Dokkum, W. (author), Schouten, A. (author), Jong de -Berkhout, P. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Over a period of 2.5 yr, 221 different food items of a 'market basket' of 18-yr-old males were purchased every 3 months. In total, 10 market baskets were collected. The foodstuffs were prepared by normal methods and combined into 23 commodity groups. Homogenates were prepared from each commodity group, followed by analysis for 17 different...
article 1990
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Verkerk, P.H. (author), Vaandrager, G.J. (author), Sengers, R.C.A. (author)
In the period 1st September 1974 to 1st Januari 1989 2,511,000 infants (99.3 of all livebirths) were screened for PKU. Treatment was required in 158 of the 330 referred infants. The diagnosis of these 158 patients was PKU (137), hyperphenylalaninaemia (HPA) (19) and malignant HPA (2). Three cases had a false-negative screening result. The...
article 1990
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