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Verkerk, P.H. (author), Buitendijk, S.E. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
It is generally believed that non-differential misclassification will lead to a bias toward the null-value. However, using one graphical and one numerical example, we show that in situations where underestimation more than overestimation is the problem, non-differential misclassification may lead to a bias away from the null-value for...
article 1992
document
Verkerk, P.H. (author), TNO Preventie en Gezondheid (author)
Objective. Evaluation of the Dutch national screening programme for phenylketonuria (PKU). Design. Descriptive. Setting. Nationwide. Methods. Data on the screening were obtained from the laboratories, from the registration offices of vaccination and screening results and from the paediatricians to whom infants with positive screening values were...
article 1995
document
van Spronsen, F.J. (author), Rijn, M. (author), Dorgelo, B. (author), Hoeksma, M. (author), Bosch, A.M. (author), Mulder, M.F. (author), de Klerk, J.B.C. (author), de Koning, T. (author), Rubio-Gozalbo, M.E. (author), de Vries, M. (author), Verkerk, P.H. (author)
Background: The clinical severity of phenylalanine hydroxylase deficiency is usually defined by either pre-treatment phenylalanine (Phe) concentration or Phe tolerance at 5 years of age. So far, little is known about the course of Phe tolerance or the ability of both pre-treatment Phe and Phe tolerance at early age to predict Phe tolerance at...
article 2009
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Kamphuis, M. (author), Obenhuijsen, N.H. (author), van Dommelen, P. (author), van Buuren, S. (author), Verkerk, P.H. (author), TNO Kwaliteit van Leven (author)
The main goal of this guideline for preventive child health care (PCHC) is to improve early detection of disorders that induce short stature. Based on research, evidence-based referral criteria for children aged 0-10 years with a short stature were formulated. These criteria are important for all professionals working with children, such as PCHC...
article 2010
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Breuning-Broers, J.M. (author), Deurloo, J.A. (author), Gooskens, R.H. (author), Verkerk, P.H. (author)
To investigate at what age hydrocephalus is detected and to assess the role of head circumference measurements in detecting hydrocephalus, we performed a retrospective chart review in children with hydrocephalus treated in a tertiary paediatric hospital in the Netherlands. The study group contained 146 patients; 38 patients (31%) were referred...
article 2014
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Diepeveen, F.B. (author), Dusseldorp, E. (author), Bol, G.W. (author), Oudesluys-Murphy, A.M. (author), Verkerk, P.H. (author)
This study established predictive properties of single language milestones for specific language impairment (SLI) after the age of four, as these had not previously been reported in the literature. Methods In this nested case-control study, children attending special needs schools for severe speech and language difficulties were matched with...
article 2016
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