document

How should a virtual agent present psychoeducation? Influence of verbal and textual presentation on adherence

Tielman, M.L. (author), Neerincx, M.A. (author), van Meggelen, M. (author), Franken, I. (author), Brinkman, W.P. (author)

BACKGROUND AND OBJECTIVE: With the rise of autonomous e-mental health applications, virtual agents can play a major role in improving trustworthiness, therapy outcome and adherence. In these applications, it is important that patients adhere in the sense that they perform the tasks, but also that they adhere to the specific recommendations on...

article 2017

document

On Kramers' general theory of Brownian motion

Brinkman, H.C. (author), Centraal Laboratorium TNO (author)

Kramer's general theory of Brownian motion 1) based on a diffusion equation in phase space is discussed from the standpoint of statistical thermodynamics. It is concluded that for particles moving in a medium in equilibrium the restrictions imposed by the second law of thermodynamics limit Kramer's diffusion equation to a slight generalisation...

article 1957

document

Distributed collaborative situation-map making for disaster response

Gunawan, L.T. (author), Alers, H. (author), Brinkman, W.P. (author), Neerincx, M.A. (author)

A situation map that shows the overview of a disaster situation serves as a valuable tool for disaster response teams. It helps them to orientate their location and to make disaster response decisions. It is, however, a complicated task to rapidly generate a complete and comprehensive situation map of a disaster area, particularly due to the...

article 2011

document

Monitoring the actual carrier gas flow during large-volume on-column injections in gas chromatography as a means to automate closure of the solvent vapour exit

Hankemeier, T. (author), Kok, S.J. (author), Vreuls, R.J.J. (author), Brinkman, U.A.Th. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1998

document

On-line solid phase extraction-gas chromatography-cryotrapping-infrared spectrometry for the trace-level determination of microcontaminants in aqueous samples

Hankemeier, T. (author), Hooijschuur, E. (author), Vreuls, R.J.J. (author), Brinkman, U.A.Th. (author), Visser, T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)

A large-volume on-column GC-cryotrapping-IR system was developed for injections of up to 100 μl of organic extracts. Considerable reduction of the solvent-and-water background and enhanced analyte detectability was achieved by using an open-split interface between the GC column and the IR detector and improving the leak-tightness of the system....

article 1998

document

At-line solid-phase extraction coupled to capillary electrophoresis: Determination of amphoteric compounds in biological samples

Veraart, J.R. (author), Gooijer, C. (author), Lingeman, H. (author), Velthorst, N.H. (author), Brinkman, U.A.Th. (author)

article 1999

document

Data correlation in on-line solid-phase extraction-gas chromatography-atomic emission/mass spectrometric detection of unknown microcontaminants

Hankemeier, Th. (author), Rozenbrand, J. (author), Abhadur, M. (author), Vreuls, J.J. (author), Brinkman, U.A.Th. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)

A procedure is described for the (non-target) screening of hetero-atom-containing compounds in tap and waste water by correlating data obtained by gas chromatography (GC) using atomic emission (AED) and mass selective (MS) detection. Solid-phase extraction (SPE) was coupled on-line to both GC systems to enable the determination of...

article 1998

document

Use of a presolvent to include volatile organic analytes in the application range of on-line solid-phase extraction-gas chromatography-mass spectrometry

Hankemeier, Th. (author), van Leeuwen, S.P.J. (author), Vreuls, R.J.J. (author), Brinkman, A.Th. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1998

document

At-line spe-gc-ms of micropollutants in water using the prepstation

Hankemeier, Th. (author), Steketee, P.C. (author), Vreuls, J.J. (author), Brinkman, U.A.T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)

An automated at-line SPE-GC-MS system for the determination of micropollutants in aqueous samples, which is based on the PrepStation and uses large-volume on-column injections, has been redesigned. A cartridge made from stainless steel and polychlorotrifluoroethylene and a 2-needle system was constructed which allow the determination of...

article 1999

document

An expressive virtual audience with flexible behavioral styles

Kang, N. (author), Brinkman, W.P. (author), van Riemsdijk, M.B. (author), Neerincx, M.A. (author)

Currently, expressive virtual humans are used in psychological research, training, and psychotherapy. However, the behavior of these virtual humans is usually scripted and therefore cannot be modified freely at runtime. To address this, we created a virtual audience with parameterized behavioral styles. This paper presents a parameterized...

article 2013

document

Gas chromatography of organic microcontaminants using atomic-emission and mass spectrometry detection

Mol, H.G.J. (author), Hankemeier, T. (author), Brinkman, U.A.T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)

article 1999

document

Non-aqueous capillary electrophoresis of biological samples after at-line solid-phase extraction

Veraart, J.R. (author), Reinders, M.C. (author), Lingeman, H. (author), Brinkman, U.A.Th. (author)

article 2000

document

Determination of hydrolysis products of sulfur mustards by reversed-phase microcolumn liquid chromatography coupled on-line with sulfur flame photometric detection and electrospray ionization mass spectrometry using large-volume injections and peak compression

Hooijschuur, E.W.J. (author), Kientz, C.E. (author), Hulst, A.G. (author), Brinkman, U.A.T. (author), Prins Maurits Laboratorium TNO (author)

On-line coupling of reversed-phase microcolumn liquid chromatography (micro-RPLC) and sulfur-selective flame photometric detection (S-FPD) was studied for the selective and direct determination of thiodiglycol, bis(2- hydroxyethylthio)methane, 1,2-bis(2-hydroxyethylthio)ethane, 1,3-bis(2- hydroxyethylthio)propane, and 1,4-bis(2-hydroxyethylthio...

article 2000

document

Analytical strategies for residue analysis of veterinary drugs and growth-promoting agents in food-producing animals - A review

Stolker, A.A.M. (author), Brinkman, U.A.T. (author), TNO Kwaliteit van Leven (author)

After a brief introduction into the field of veterinary drugs and growth-promoting agents, the most important EU regulations and directives for the inspection of food-producing animals and animal products regarding the residue control of these substances are presented and discussed. Main attention in the review is on the methods of analysis in...

article 2005

document

On-line dialysis-SPE-CE of acidic drugs in biological samples

Veraart, J.R. (author), Groot, M.C.E. (author), Gooijer, C. (author), Lingeman, H. (author), Velthorst, N.H. (author), Brinkman, U.A.Th. (author)

article 1999

document

Ballistic supercurrent discretization and micrometer-long Josephson coupling in germanium

Hendrickx, N.W. (author), Tagliaferri, M.L.V. (author), Kouwenhoven, M. (author), Li, R. (author), Franke, D.P. (author), Sammak, A. (author), Brinkman, A. (author), Scappucci, G. (author), Veldhorst, M. (author)

We fabricate Josephson field-effect transistors in germanium quantum wells contacted by superconducting aluminum and demonstrate supercurrents carried by holes that extend over junction lengths of several micrometers. In superconducting quantum point contacts we observe discretization of supercurrent, as well as Fabry-Perot resonances,...

article 2019

document

On-line coupling of immunoaffinity-based solid-phase extraction and gas chromatography for the determination of s-triazines in aqueous samples

Dallüge, J. (author), Hankemeier, T. (author), Vreuls, R.J.J. (author), Brinkman, U.A.Th. (author)

article 1999

document

Gas chromatography of organic microcontaminants using atomic emission and mass spectrometric detection combined in one instrument (GC-AED/MS)

Mol, H.G.J. (author), Hankemeier, T. (author), Brinkman, U.A.T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)

This study describes the coupling of an atomic-emission detector and mass-spectrometric detector to a single gas chromatograph. Splitting of the column effluent enables simultaneous detection by atomic-emission detection (AED) and mass spectrometry (MS) and yields a powerful system for the target and non-target analysis of gas chromatography (GC...

article 1999

document

Coupling of biological sample handling and capillary electrophoresis

Veraart, J.R. (author), Lingeman, H. (author), Brinkman, U.A.Th. (author)

article 1999

document

Lessons learned from the development of technological support for PTSD prevention: A review

Vakili, V. (author), Brinkman, W.P. (author), Neerincx, M.A. (author)

This review2 describes the state-of-the-arttechnologiesthat support mental resilience training for PTSD prevention. It characterizes four current systems across training approaches; seeks insights via interviews with the systemdevelopers; and extracts from thesea set of essential guidelines for future developers. The guidelines include four...

article 2012