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Joosten, M.M. (author), TNO Kwaliteit van Leven (author), KvL (author)
doctoral thesis 2010
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Molhoek, E.M. (author)
doctoral thesis 2011
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Verhave, P.S. (author)
doctoral thesis 2011
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van den Heuvel, M. (author)
doctoral thesis 2011
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Balvers, M.G.J. (author)
doctoral thesis 2012
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Westerhout, J. (author)
In the development of drugs for the treatment of central nervous system (CNS) disorders, the prediction of human CNS drug action is a big challenge. Direct measurement of brain extracellular fluid (brainECF) concentrations is highly restricted in human. Therefore, unbound drug concentrations in human cerebrospinal fluid (CSF) are used as a...
doctoral thesis 2014
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Döpp, C. (author)
Het proefschrift beschrijft een studie naar de implementatie van de effectief gebleken ergotherapie-interventie voor mensen met dementie en hun mantelzorgers (EDOMAH). Middels een cluster-RCT werd de huidige post-HBO cursus voor ergotherapeuten vergeleken met een multi-professionele strategie gericht op ergotherapeuten, artsen en managers. De...
doctoral thesis 2015
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Liang, W. (author)
Overload of nutrients can lead to diet-induced inflammation, also called metabolic inflammation, which is thought to play an important role in many metabolic diseases, including the development of nonalcoholic fatty liver disease (NAFLD). NAFLD encompasses a spectrum of pathologies that range from simple hepatic steatosis to nonalcoholic...
doctoral thesis 2015
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de Wilde, J.A. (author)
For South Asian adults lowered BMI cut-offs for overweight and obesity are recommended as these are more in agreement with their body composition (low muscle mass, high fat mass) and the considerably higher risk of cardiovascuar and metabolic disease. For South Asian children living in a Western country lowered BMI norms have not been...
doctoral thesis 2015
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Hiemstra-van Mastrigt, S. (author)
This thesis provides new knowledge on how to design comfortable passenger seats and provides recommendations for design and research. Although the first studies on passenger seat comfort appeared already 40 years ago, the activities and context have changed since then. In this thesis, relationships have been mapped out between activities ...
doctoral thesis 2015
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Offerhaus, P.M. (author)
The number of obstetric interventions during normal term labour is increasing in the Netherlands, for instance for augmentation of labour and epidurals. Offerhaus also observed that the number of unplanned caesarean sections increased for healthy women who were pregnant and gave birth for the first time. These changes were not accompanied by...
doctoral thesis 2015
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Schonbeck, Y. (author)
Background: Monitoring human growth is important. It is used to detection of abnormal growth trajectories of children, which may reflect nutritional problems or underlying illness. In a larger population, it can provide information about the health status of this population, for example the prevalence of overweight and obesity, or the mean...
doctoral thesis 2015
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Leijten, F.R.M (author)
Due to an ageing society, an increasing retirement age, and high prevalence of chronic health problems among older persons, it is important to understand how older employees [with health problems] can work for longer and productively, often this is termed ‘sustainable employability’. This context brought about the research presented in this...
doctoral thesis 2015
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Simons, M. (author)
In dit proefschrift wordt onderzocht in hoeverre beweeggames kunnen bijdragen aan de preventie van overgewicht bij 12- tot 16-jarigen. Uit het onderzoek blijkt dat dit soort games nog niet kunnen concurreren met de gangbare computergames en daarom niet aantrekkelijk genoeg zijn voor jongeren om naar over te stappen. Simons raadt de fabrikanten...
doctoral thesis 2015
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Morrison, M.C. (author)
Over the past few decades it has become increasingly clear that inflammation – a normal and essential defense mechanism that protects the body from infection and injury – can also be triggered by nutrients and dietary surplus, an inflammatory state that is referred to as metabolic inflammation. This chronic low-grade inflammatory state is...
doctoral thesis 2016
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Sanders, J.M.A.S. (author)
Sustainable employability has recently become a topical issue in HR literature. Two major developments are responsible for this increased attention. The first is contextual change, requiring businesses to adapt to faster changing markets, causing rapid shifts in the demand for labour and skills. These shifts have severe consequences for the...
doctoral thesis 2016
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van Egmond, M.P. (author)
In Nederland krijgen jaarlijks 40.000 mensen in de werkende leeftijd een diagnose kanker. Uit onderzoek blijkt tevens dat het aantal mensen dat vanwege kanker een ziektewet- of WIA-uitkering aanvraagt, al jaren stijgt. Als je kanker krijgt heb je een kwetsbare positie op de arbeidsmarkt. Zelfs 1 op de 4 Nederlandse kankerpatiënten verliest zijn...
doctoral thesis 2016
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van Houtem, C.M.H.H. (author)
This thesis aimed to increase the knowledge about severe forms of anxiety, gagging and fainting in dentistry and to investigate whether these phenomena are overlapping or separate constructs. In Chapter 2 a literature review of twin studies showed that the estimated heritability of specific phobias and fears varied widely. In Chapter 3 a...
doctoral thesis 2016
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de Wind, A. (author)
Many developed countries are confronted with ageing populations, due to the increase in life expectancy and long-term decline in fertility rates. As a consequence, the ratio of the retired elderly to the active working population increases. This puts a pressure on the social security system, and causes tension in the solidarity between...
doctoral thesis 2016
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Buist, H.E. (author)
doctoral thesis 2016
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