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Ding, S. (author), Ward, H. (author), Tukker, A. (author)The introduction of new information technologies has started reshaping global industrial sectors and supply chains. Due to the introduction of the Internet of Things (IoT) real-time management strategies have been adopted by the global logistics industry, turning the branch into an intelligent service supplier. This paper assesses the influence...article 2023
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Künnemann, H. (author), Phillipson, F. (author)The problem of finding the maximum weighted cycle in a directed graph map to solve optimization problems is N P-hard, implying that approaches in classical computing are inefficient. Here, Quantum computing might be a promising alternative. Many current approaches to the quantum computer are based on a Quadratic Unconstrained Binary Optimization...article 2023
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Wang, R. (author), Damanik, F. (author), Kuhnt, T. (author), Jaminon, A. (author), Hafeez, S. (author), Liu, H. (author), Ippel, H. (author), Dijkstra, P.J. (author), Bouvy, N. (author), Schurgers, L. (author), ten Cate, A.T. (author), Dias, A. (author), Moroni, L. (author), Baker, M.B. (author)Digital light processing (DLP) is an accurate and fast additive manufacturing technique to produce a variety of products, from patient-customized biomedical implants to consumer goods. However, DLP's use in tissue engineering has been hampered due to a lack of biodegradable resin development. Herein, a library of biodegradable poly(esters)...article 2023
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Künnemann, H. (author), Phillipson, F. (author)The problem of finding the maximum weighted cycle in a directed graph map to solve optimization problems is (Formula presented.) -hard, implying that approaches in classical computing are inefficient. Here, Quantum computing might be a promising alternative. Many current approaches to the quantum computer are based on a Quadratic Unconstrained...article 2023
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de Rond, V. (author), Hulzinga, F. (author), Baggen, R.J. (author), de Vries, A. (author), Orban de Xivry, J.J. (author), Pantall, A. (author), Nieuwboer, A. (author)urpose: Postural control deteriorates with age, especially under dual-task conditions. It is currently unknown how a challenging virtual reality weight-shifting task affects lower back muscle activity. Hence, this study investigated erector spinae neuromuscular control during mediolateral weight-shifting as part of an exergame during single- (ST...article 2023
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- Kastelein, R.A. (author), de Jong, C.A.F. (author), Tougaard, J. (author), Helder-Hoek, L. (author), Defillet, L.N. (author) article 2022
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von Benda-Beckmann, A.M. (author), Ketten, D.R. (author), Lam, F.P.A. (author), de Jong, C.A.F. (author), Muller, R.A.J. (author), Kastelein, R.A. (author)Application of a kurtosis correction to frequency-weighted sound exposure level (SEL) improved predictions of risk of hearing damage in humans and terrestrial mammals for sound exposures with different degrees of impulsiveness. To assess whether kurtosis corrections may lead to improved predictions for marine mammals, corrections were applied to...article 2022
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- van Dommelen, P. (author), van Lonkhuijsen, M. (author), Bakker, R. (author) public lecture 2021
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van der Pal, S.M. (author), van der Meulen, S.A. (author), Welters, S.M. (author), Bakker, L.A. (author), de Groot, C.J.M. (author), van Kaam, A.H. (author), Verrips, G.H.W. (author)Evidence suggests that increased survival over the last decades of very preterm (VPT; gestational age < 32 weeks)– and very low birth weight (VLBW; birth weight < 1500 g)–born infants is not matched by improved outcomes. The objective of our study was to evaluate the reproductive rate, fertility, and pregnancy complications in 35-year-old VPT...article 2021
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Memelink, R.G. (author), Pasman, W.J. (author), Bongers, A. (author), Tump, A. (author), van Ginkel, A. (author), Tromp, W. (author), Wopereis, S. (author), Verlaan, S. (author), den Bosch, J.V.V. (author), Weijs, P.J.M. (author)Background: Weight loss is key to treatment of older adults with obesity and type 2 diabetes, but also a risk for muscle mass loss. This study investigated whether a whey protein drink enriched with leucine and vitamin D could preserve muscle mass and improve glycemic control during combined lifestyle intervention in this population. Methods:...article 2021
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Piedvache, A. (author), van Buuren, S. (author), Barros, H. (author), Ribeiro, A.I. (author), Draper, E. (author), Zeitlin, J. (author), EPICE Research group, (author)Background: Loss to follow-up is a major challenge for very preterm (VPT) cohorts; attrition is associated with social disadvantage and parents with impaired children may participate less in research. We investigated the impact of loss to follow-up on the estimated prevalence of neurodevelopmental impairment in a VPT cohort using different...article 2021
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Keemink, A.Q.L. (author), Brug, T.J.H. (author), van Asseldonk, E.H.F. (author), Wu, A.R. (author), van der Kooij, H. (author)Active prosthetic and orthotic devices have the potential to increase quality of life for individuals with impaired mobility. However, more research into human-like control methods is needed to create seamless interaction between device and user. In forward simulations the reflex-based neuromuscular model (RNM) by Song and Geyer shows promising...article 2021
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Kiesswetter, E. (author), Keijser, B.J.F. (author), Volkert, D. (author), Visser, M. (author)Background: To prevent involuntary weight loss in older people, the knowledge about factors affecting body weight (BW) is essential. Therefore, we aimed to investigate the longitudinal associations of multiple oral health aspects with BW in community-dwelling older adults. Methods: This analysis is based on prospective data with a 10-year follow...article 2020
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van den Dries, M.A. (author), Guxens, M. (author), Spaan, S. (author), Ferguson, K.K. (author), Philips, E. (author), Santos, S. (author), Jaddoe, V.W.V. (author), Ghassabian, A. (author), Trasande, L. (author), Tiemeier, H. (author), Pronk, A. (author)BACKGROUND: Prenatal exposures to phthalates and bisphenols are associated with impaired brain development in animals. However, epidemiological studies investigating the association between prenatal phthalate or bisphenol exposure and cognition have produced mixed findings and mostly had modest sample sizes and measured the exposure during the...article 2020
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Sewell, F. (author), Strupp, C. (author), van der Laan, J.W. (author), Wolf, D.C. (author), Wolterink, G. (author), Woutersen, R. (author), Zvonar, Z. (author), Heusinkveld, H. (author), Braakhuis, H. (author)Currently the only methods for non-genotoxic carcinogenic hazard assessment accepted by most regulatory authorities are lifetime carcinogenicity studies. However, these involve the use of large numbers of animals and the relevance of their predictive power and results has been scientifically challenged. With increased availability of innovative...article 2020
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van der Pal, S.M. (author), Steinhoff, M. (author), Grevinga, M. (author), Wolke, D. (author), Verrips, G.H.W. (author)This systematic review was performed in the context of EU‐project RECAP (www.recap-preterm.eu) and thus with funding from the European Commission; Horizon 2020; Grant Number: 733280. Aim. To establish differences in health‐related quality of life (HRQoL) in adults born term and those born very preterm (VPT) and/or with a very low birth weight ...article 2020
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Memelink, R. (author), Bongers, A. (author), Pasman, W. (author), van Rijmenam, M. (author), Wopereis, S. (author), Verlaan, G. (author), de Vogel Van den Bosch, J (author), Weijs, P.J.M. (author)Objectives. Weight loss is a key element in the treatment of obesity and type 2 diabetes (T2D), but also a risk factor for lean mass (LM) loss in older adults. We evaluated whether a whey protein drink enriched with leucine and vitamin D preserved LM during 3-month lifestyle intervention and whether effects sustained during 6 months follow-up...article 2020
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Heusinkveld, H. (author), Braakhuis, H. (author), Gommans, R. (author), Botham, P. (author), Corvaro, M. (author), van der Laan, J.W. (author), Lewis, D. (author), Madia, F. (author), Manou, I. (author), Schorsch, F. (author), Wolterink, G. (author), Woutersen, R. (author), Corvi, R. (author), Mehta, J. (author), Luijten, M. (author)Chemical substances are subjected to assessment of genotoxic and carcinogenic effects before being marketed to protect man and the environment from health risks. For agrochemicals, the long-term rodent carcinogenicity study is currently required from a regulatory perspective. Although it is the current mainstay for the detection of nongenotoxic...article 2020
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Krone, T. (author), Boessen, R. (author), Bijlsma, S. (author), van Stokkum, R. (author), Clabbers, N.D.S. (author), Pasman, W.J. (author)Background. N-of-1 designs gain popularity in nutritional research because of the improving technological possibilities, practical applicability and promise of increased accuracy and sensitivity, especially in the field of personalized nutrition. This move asks for a search of applicable statistical methods. Objective. To demonstrate the...article 2020
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Pasman, W.J. (author), Memelink, R.G. (author), den Bosch, J.V.V. (author), Begieneman, M.P.V. (author), van den Brink, W.J. (author), Weijs, P.J.M. (author), Wopereis, S. (author)Background: Recent research showed that subtypes of patients with type 2 diabetes may differ in response to lifestyle interventions based on their organ-specific insulin resistance (IR). (2) Methods: 123 Subjects with type 2 diabetes were randomized into 13-week lifestyle intervention, receiving either an enriched protein drink (protein+) or an...article 2020