Searched for: subject:"weight%5C+reduction"
(1 - 20 of 29)

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Memelink, R. (author), Bongers, A. (author), Pasman, W. (author), van Rijmenam, M. (author), Wopereis, S. (author), Verlaan, G. (author), de Vogel Van den Bosch, J. (author), Weijs, P.J.M. (author)
Objectives. Weight loss is a key element in the treatment of obesity and type 2 diabetes (T2D), but also a risk factor for lean mass (LM) loss in older adults. We evaluated whether a whey protein drink enriched with leucine and vitamin D preserved LM during 3-month lifestyle intervention and whether effects sustained during 6 months follow-up...
article 2020
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Fiamoncini, J. (author), Yiorkas, A.M. (author), Gedrich, K. (author), Rundle, M. (author), Alsters, S.I. (author), Roeselers, G. (author), van den Broek, T.J. (author), Clavel, T. (author), Lagkouvardos, I. (author), Wopereis, S. (author), Frost, G. (author), van Ommen, B. (author), Blakemore, A.I. (author), Daniel, H. (author)
Bile acids (BA) are signaling molecules with a wide range of biological effects, also identified among the most responsive plasma metabolites in the postprandial state. We here describe this response to different dietary challenges and report on key determinants linked to its interindividual variability. Healthy men and women (n = 72, 62 ± 8 yr,...
article 2017
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Rubenstein, C.D. (author), den Hartog, E.A. (author), Deaton, A.S. (author), Bogerd, C.P. (author), de Kant, S. (author)
A major concern for responders to hazardous materials (HazMat) incidents is the heat strain that is caused by fully encapsulated impermeable chemical protective suits. In a research project, funded by the US Department of Defense, the thermal strain experienced when wearing these suits was studied. One particular area of interest was the fluid...
article 2017
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Stroeve, J.H.M. (author), Saccenti, E. (author), Bouwman, J. (author), Dane, A. (author), Strassburg, K. (author), Vervoort, J. (author), Hankemeier, T. (author), Astrup, A. (author), Smilde, A.K. (author), van Ommen, B. (author), Saris, W.H.M. (author)
Objective: Aim is to predict successful weight loss by metabolic signatures at baseline and to identify which differences in metabolic status may underlie variations in weight loss success. Methods: In DiOGenes, a randomized, controlled trial, weight loss was induced using a low calorie diet (800 kcal) for 8-weeks. Men (N5236) and women (N5431)...
article 2016
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Shekhar, A. (author), Bolech, M. (author), Prasanth, V. (author), Bauer, P. (author)
Economic viability of on-road charging strongly depends on the choice of inductive power transfer (IPT) system configuration (static or dynamic charging), charging power level and the percentage road coverage of dynamic charging. In this paper, a case study is carried out to determine the expected investment costs involved in installing the on...
conference paper 2015
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Shekhar, A. (author), Prasanth, V. (author), Bauer, P. (author), Bolech, M. (author)
An analytical estimation of driving range of electric vehicles (EVs) with contactIess on-road charging system is presented in this paper. Inductive power transfer (IPT) systems with different configurations (static, dynamic), power levels and road coverage have different (and non-linear) impact on the driving range. A generic methodology has...
conference paper 2015
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Morrison, M.C. (author), Kleemann, R. (author)
Obesity is associated with a chronic low-grade inflammatory state that drives the -development of obesity-related co-morbidities such as insulin resistance/type 2 diabetes, non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease. This metabolic inflammation is thought to originate in the adipose tissue, which becomes inflamed and...
article 2015
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Boon, M.R. (author), Kooijman, S. (author), van Dam, A.D. (author), Pelgrom, L.R. (author), Berbée, J.F.P. (author), Visseren, C.A.R. (author), van Aggele, R.C. (author), van den Hoek, A.M. (author), Sips, H.C.M. (author), Lombès, M. (author), Havekes, L.M. (author), Tamsma, J.T. (author), Guigas, B. (author), Meijer, O.C. (author), Jukema, J.W. (author), Rensen, P.C.N. (author)
The endocannabinoid system is an important player in energy metabolism by regulating appetite, lipolysis, and energy expenditure. Chronic blockade of the cannabinoid 1 receptor (CB1R) leads to long-term maintenance of weight loss and reduction of dyslipidemia in experimental and human obesity. The molecular mechanism by which CB1R blockade...
article 2014
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van Genugten, G.L. (author), van Empelen, E.P. (author), Boon, B. (author), Borsboom, G. (author), Visscher, T. (author), Oenema, A. (author)
article 2013
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Mariman, R. (author), Kremer, S.H.A. (author), van Erk, M. (author), Lagerweij, T. (author), Koning, F. (author), Nagelkerken, L. (author)
Background: Host-microbiota interactions in the intestinal mucosa play a major role in intestinal immune homeostasis and control the threshold of local inflammation. The aim of this study was to evaluate the efficacy of probiotics in the recurrent trinitrobenzene sulfonic acid (TNBS)-induced colitis model and gain more insight into protective...
article 2012
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Tonk, E.C.M. (author), de Groot, D.M.G. (author), Penninks, A.H. (author), Waalkens - Berendsen, I.D.H. (author), Wolterbeek, A.P.M. (author), Slob, W. (author), Piersma, A.H. (author), van Loveren, H. (author), TNO Kwaliteit van Leven (author)
Current developmental and reproductive toxicity protocols include only a limited set of parameters for effects on the developing immune system. In this study, a wide range of immunological parameters were included in a pre- and postnatal developmental toxicity study. Dose-response data were compared to determine the relative sensitivity of...
article 2010
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Oranje, A.P. (author), Verbeek, R. (author), Verzaal, P. (author), Haspels, I. (author), Prens, E. (author), Nagelkerken, L. (author), TNO Kwaliteit van Leven (author)
Background: Wet-wrap treatment (WWT) with diluted topical steroids is widely used in atopic dermatitis (AD). Mice with transgenic overexpression of human apolipoprotein C1 (APOC1) in the liver and the skin are not only characterized by hyperlipidaemia and raised IgE levels, but also by pruritic dermatitis and a disturbed skin barrier function,...
article 2009
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Kaman, W.E. (author), Wolterink, A.F.W.M. (author), Bader, M. (author), Boele, L.C.L. (author), van der Kleij, D. (author), TNO Defensie en Veiligheid (author)
The endogenous danger signal bradykinin was recently found implicated in the development of immunity against parasites via dendritic cells. We here report an essential role of the B2 (B2R) bradykinin receptor in the early immune response against Listeria infection. Mice deficient in B2R (B2R-/- mice) were shown to suffer from increased hepatic...
article 2009
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Pelleboer, R.A.A. (author), Bontemps, S.T.H. (author), Verkerk, P.H. (author), van Dommelen, P. (author), Pereira, R.R. (author), van Wouwe, J.P. (author), TNO Kwaliteit van Leven (author)
Aims: To estimate the incidence and clinical characteristics in hospital admissions due to dehydration or undernutrition and their laboratory evaluation and treatment outcome in exclusively breastfed infants. Methods: All hospital admissions during the first 3 months of life assessed by the Dutch Paediatric Surveillance Unit (DPSU) between mid...
article 2009
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van Wier, M.F. (author), Arins, G.A.M. (author), Dekkers, J.C. (author), Hendriksen, I.J.M. (author), Smid, T. (author), van Mechelen, W. (author), TNO Kwaliteit van Leven (author)
Background. The work setting provides an opportunity to introduce overweight (i.e., Body Mass Index 25 kg/m2) adults to a weight management programme, but new approaches are needed in this setting. The main purpose of this study was to investigate the effectiveness of lifestyle counselling by phone or e-mail on body weight, in an overweight...
article 2009
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van Dommelen, P. (author), van Wouwe, J.P. (author), Breuning-Boers, J.M. (author), van Buuren, S. (author), Verkerk, P.H. (author), TNO Kwaliteit van Leven (author)
Objective: The validity of the rule of thumb that infants may have a weight loss of 10% in the first days after birth is unknown. We assessed the validity of this and other rules to detect breast-fed infants with hypernatraemic dehydration. Design: A reference chart for relative weight change was constructed by the LMS method. The reference...
article 2007
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Breuning-Boers, J.M. (author), van Dommelen, P. (author), van Wouwe, J.P. (author), Verkerk, P.H. (author)
Objective. To determine the relationship between serum sodium concentration and weight loss as well as residual symptoms in newborns with hypernatremic dehydration caused by insufficient breastfeeding; and to determine the sensitivity of the following rule of thumb 'if weight loss is less than 10%, the baby does not have hypernatremic...
article 2006
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Hendriks, H.F.J. (author), Pasman, W.J. (author), Blom, W.A.M. (author), Stafleu, A. (author), TNO Kwaliteit van Leven (author)
article 2006
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Schaafsma, G. (author), TNO Kwaliteit van Leven (author)
Loss of muscle mass as a consequence of changes in protein metabolism during periods of catabolic stress is a serious complication in a variety of conditions. These conditions are weight loss programs, sarcopenia in the elderly and several clinical states. It appears from many studies that improved protein nutrition by ingestion of high-quality...
article 2006
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Lina, B. (author), Korte, H. (author), Nyman, L. (author), Unkila, M. (author), TNO Kwaliteit van Leven (author)
Plant lignan 7-hydroxymatairesinol (7-HMR) is a novel precursor of the mammalian lignan enterolactone. A 13 week toxicity study at dietary levels of 0, 0.25, 1, and 4% (w/w) of potassium acetate complex of 7-HMR (HMRlignan) was conducted in the Wistar rat. These dietary levels resulted in an average daily intake of 160, 640, and 2600 mg...
article 2005
Searched for: subject:"weight%5C+reduction"
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