Searched for: subject:"therapy"
(1 - 20 of 218)

Pages

document
Spataru, A. (author), van Dommelen, P. (author), Arnaud, L. (author), Le Masne, Q. (author), Quarteroni, S. (author), Koledova, E.B. (author)
Background: Long-term persistence of use and starting at the earliest possible age are associated with attainment of near-normal adult or final height in children who are treated with growth hormone therapy. However, there are many factors associated with a lack of persistence. Our aim was to study persistence of use in children with growth...
article 2021
document
Araujo, M. (author), van Dommelen, P. (author), Koledova, E.B. (author), Srivastava, J. (author)
The problem of consistent therapy adherence is a current challenge for health informatics, and its solution can increase the success rate of treatments. Here we show a methodology to predict, at individual-level, future therapy adherence for patients receiving daily injections of growth hormone (GH) therapy for GH deficiency. Our proposed model...
article 2021
document
Spataru, A. (author), van Dommelen, P. (author), Arnaud, L. (author), Le Masne, Q. (author), Quarteroni, S. (author), Koledova, E.B. (author)
Background: Suboptimal adherence to recombinant human growth hormone (r-hGH) treatment can lead to suboptimal clinical outcomes. Being able to identify children who are at risk of suboptimal adherence in the near future, and take adequate measures to support adherence, may maximize clinical outcomes. Our aim was to develop a model based on data...
article 2021
document
Bal, M. (author), Benders, J. (author), Dhondt, S. (author), Vermeerbergen, L. (author)
Despite the emergence of head-worn displays at work around forty years ago, few studies have appeared about their impact on job content. To investigate this, a systematic literature review was conducted on these devices and job content, defined as job demands and controls. In total, 3481 studies were identified using five scientific databases....
article 2020
document
Bohnert, S. (author), van den Berg, R.M. (author), Mikler, J. (author), Klaassen, S.D (author), Joosen, M.J.A. (author)
Organophosphorus nerve agents (NA) inhibit acetylcholinesterase (AChE) which results in the over-stimulation of both the central and peripheral nervous systems, creating a toxic syndrome that can be lethal if left untreated (Cannard, 2006). It is standard practice to treat Sarin (GB) intoxication with an oxime, an antimuscarinic such as atropine...
article 2020
document
Wickramasinghe, K. (author), Mathers, J.C. (author), Wopereis, S. (author), Marsman, D.S. (author), Griffiths, J.C. (author)
Across the globe, there has been a marked increase in longevity, but significant inequalities remain. These are exacerbated by inadequate access to proper nutrition and health care services and to reliable information to make the decisions related to nutrition and health care. Many in economically developing as well as developed societies are...
article 2020
document
Pouwer, M.G. (author), Pieterman, E.J. (author), Worms, N. (author), Keijzer, N. (author), Jukema, J.W. (author), Gromada, J. (author), Gusarova, V. (author), Princen, H.M.G. (author)
Atherosclerosis-related cardiovascular disease causes nearly 20 million deaths annually. Most patients are treated after plaques develop, so therapies must regress existing lesions. Current therapies reduce plaque volume, but targeting all apoB-containing lipoproteins with intensive combinations that include alirocumab or evinacumab-monoclonal...
article 2020
document
Gjengedal, R.G.H. (author), Reme, S.E. (author), Osnes, K. (author), Lagerveld, S. (author), Blonk, R.W.B. (author), Sandin, K. (author), Berge, T. (author), Hjemdal, O. (author)
BACKGROUND: Common mental disorders (CMD) are leading causes of sickness absence. Treatments for CMD that both reduce symptoms and support work participation urgently need to be developed. OBJECTIVE: Determine the potential effects of work-focused therapy combining work interventions with either meta cognitive therapy or cognitive behavioural...
article 2020
document
Landman, A. (author), Davies, S. (author), Groen, E.L. (author), van Paassen, M.M.R. (author), Lawson, N.J. (author), Bronkhorst, A.W. (author), Mulder, M. (author)
We hypothesized that an incorrect expectation due to spatial disorientation may induce roll reversal errors. To test this, an in-flight experiment was performed, in which forty non-pilots rolled wings level after receiving motion cues. A No-leans condition (subthreshold motion to a bank angle) was included, as well as a Leans-opposite condition ...
article 2019
document
Brenninkmeijer, V. (author), Lagerveld, S. (author), Blonk, R.W.B. (author), Schaufeli, W.B. (author), Wijngaards-de Meij, L.D.N.V. (author)
Purpose This study examined who benefits most from a cognitive behavioural therapy (CBT)-based intervention that aims to enhance return to work (RTW) among employees who are absent due to common mental disorders (CMDs) (e.g., depression, anxiety, or adjustment disorder). We researched the influence of baseline work-related self-efficacy and...
article 2019
document
Tielman, M.L. (author), Neerincx, M.A. (author), Brinkman, W.P. (author)
BACKGROUND: Systems incorporating virtual agents can play a major role in electronic-mental (e-mental) health care, as barriers to care still prevent some patients from receiving the help they need. To properly assist the users of these systems, a virtual agent needs to promote motivation. This can be done by offering motivational messages....
article 2019
document
Woudstra, L. (author), Meinster, E. (author), van Haren, L. (author), Kay, A.M. (author), Kooman, M. (author), Belien, J.A.M. (author), Morrison, M.C. (author), van Rossum, A.C. (author), Helder, M.N. (author), Juffermans, J.M. (author), Niessen, H.W.M. (author), Krijnen, P.A.J. (author)
Background aims. After a myocardial infarction (MI) atherosclerosis is accelerated leading to destabilization of the atherosclerotic plaque. mesenchymal stromal cells are a promising therapeutic option for atherosclerosis. Previously, we demonstrated a novel stem cell delivery technique, with adipose stem cells coupled to microbubbles (i.e.,...
article 2018
document
Polderdijk, M. (author), Vanderfeesten, I. (author), Erasmus, J. (author), Traganos, K. (author), Bosch, T. (author), van Rhijn, G. (author), Fahland, D. (author)
Process models are schematic representations of business processes and support analysis for process redesign. A process model may be enhanced with additional information to further improve its analytical value (e.g. costs, throughput times, etc.). To support analysis of human factors in manufacturing processes, this paper introduces a new...
conference paper 2018
document
Fu, J. (author), van Wietmarschen, H.A. (author), van der Kooij, A. (author), Cuppen, B.V.J. (author), Schroën, Y. (author), Marijnissen, A.K. (author), Meulman, J.J. (author), Lafeber, F.P.J.G. (author), van der Greef, J. (author)
Introduction: Biological therapies have greatly improved the treatment efficacy in rheumatoid arthritis (RA). However, in clinical practice a significant proportion of patients experience an inadequate response to treatment. The aim of this study is to classify responding and non-responding rheumatoid arthritis patients treated with biological...
article 2018
document
Aldi, S. (author), Matic, L.P. (author), Hamm, G. (author), van Keulen, D. (author), Tempel, D. (author), Holmstrøm, K. (author), Szwajda, A. (author), Nielsen, B. (author), Emilsson, V. (author), Ait-Belkacem, R. (author), Lengquist, M. (author), Paulsson-Berne, G. (author), Eriksson, P. (author), Lindeman, J.H.N. (author), Gool, A.J. (author), Stauber, J. (author), Hedin, U. (author), Hurt-Camejo, E. (author)
Variants in the PLPP3 gene encoding for lipid phosphate phosphohydrolase 3 have been associated with susceptibility to atherosclerosis independently of classical risk factors. PLPP3 inactivates lysophosphatidic acid (LPA), a pro-inflammatory, pro-thrombotic product of phospholipase activity. Here we performed the first exploratory analysis of...
article 2018
document
Kruisdijk, F. (author), Hendriksen, I. (author), Tak, E. (author), Beekman, A.J. (author), Hopman-Rock, M. (author)
Background: Exercise is currently seen as an effective treatment for major depressive disorder (MDD). However, existing studies have focused mainly on mild-to-moderate depression. The moderate positive effect of exercise found in meta-analyses concerning these studies differs, however, from the harsh daily clinical practice, when trying to...
article 2018
document
Westerik, N. (author), Reid, G. (author), Sybesma, W. (author), Kort, R. (author)
The probiotic Lactobacillus rhamnosus GG (LGG) can play a role in establishing a harmless relationship with Helicobacter pylori and reduce gastric pathology in East African populations. H. pylori has the ability to inhabit the surface of the mucous layer of the human stomach and duodenum. In the developing world, an estimated 51% of the...
article 2018
document
van Stee, M.F. (author), de Graaf, A.A. (author), Groen, A.K. (author)
Patients with diabetes type 2 have an increased risk for cardiovascular disease and commonly use combination therapy consisting of the anti-diabetic drug metformin and a cholesterol-lowering statin. However, both drugs act on glucose and lipid metabolism which could lead to adverse effects when used in combination as compared to monotherapy. In...
article 2018
document
Tielman, M.L. (author), Neerincx, M.A. (author), Bidarra, R. (author), Kybartas, B. (author), Brinkman, W.P. (author)
Although post-traumatic stress disorder (PTSD) is well treatable, many people do not get the desired treatment due to barriers to care (such as stigma and cost). This paper presents a system that bridges this gap by enabling patients to follow therapy at home. A therapist is only involved remotely, to monitor progress and serve as a safety net....
article 2017
document
van der Valk, E.S. (author), Smans, L.C.C.J. (author), Hofstetter, H. (author), Stubbe, J.H. (author), de Vries, M. (author), Backx, F.J.G. (author), Hermus, A.R.M.M. (author), Zelissen, P.M.J. (author)
Background: Health-related quality of life in patients with Addison's disease has been assessed in various European countries, indicating a reduced quality of life. However, no studies have addressed the impact of Addison's disease on physical activity. Objective: The aim of this study was to investigate the quality of life in Dutch patients...
article 2016
Searched for: subject:"therapy"
(1 - 20 of 218)

Pages