Searched for: subject%3A%22short%255C%2Bsurvey%22
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Gvaramia, D. (author), Blaauboer, M.E. (author), Hanemaaijer, R. (author), Everts, V. (author)
Fibrosis underlies the pathogenesis of numerous diseases and leads to severe damage of vital body organs and, frequently, to death. Better understanding of the mechanisms resulting in fibrosis is essential for developing appropriate treatment solutions and is therefore of upmost importance. Recent evidence suggests a significant antifibrotic...
article 2013
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van Buuren, S. (author), van Wouwe, J.P. (author), TNO Kwaliteit van Leven (author)
article 2008
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Tielemans, E. (author), Schaafsma, G. (author), de Heer, C. (author), Rijnders, E. (author), Groenewold, M. (author), Bouwman, Y. (author), TNO Kwaliteit van Leven (author)
article 2005
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van der Meer, J.R. (author), Tropel, D. (author), Jaspers, M. (author), TNO Voeding (author)
Engineering bacteria for measuring chemicals of environmental or toxicological concern (bioreporter bacteria) has grown slowly into a mature research area. Despite many potential advantages, current bioreporters do not perform well enough to comply with environmental detection standards. Basically, the reasons for this are the lack of...
article 2004
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den Boer, M. (author), Voshol, P.J. (author), Kuipers, F. (author), Havekes, L.M. (author), Romijn, J.A. (author), TNO Preventie en Gezondheid (author)
Epidemiological studies in humans, as well as experimental studies in animal models, have shown an association between visceral obesity and dyslipidemia, insulin resistance, and type 2 diabetes mellitus. Recently, attention has been focused on the excessive accumulation of triglycerides (TG) in the liver as part of this syndrome. In this review,...
article 2004
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Proper, K. (author), Hildebrandt, V. (author), van der Beek, A. (author), Green, B.B. (author)
Chemicals/CAS: cholesterol, 57-88-5
article 2003
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Willems, J.H.B.M. (author)
The Health Council of the Netherlands has published its advisory report on Repetitive Strain Injury (RSI). The report provides clear information on the state of this syndrome, including the definition of the problem, the epidemiology, various hypothetical pathophysiological mechanisms, occupational and personal risk factors, and possible methods...
article 2002
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Barth, P.G. (author), Hirasing, R.A. (author), TNO Preventie en Gezondheid (author)
The prevalence of the severe disease spina bifida is decreasing, but the present rate is still unacceptably high. Only one-third of women planning motherhood use the recommended folic acid, although compliance is increasing. Campaigns for the use of folic acid by these women should be intensified. This method, however, cannot completely prevent...
article 2000
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Notermans, S. (author), Hoornstra, E. (author), TNO Voeding (author)
Risk assessment is increasingly used as a scientific process to assess the potential for adverse health effects to occur and as a basis for management of unacceptable risks. For each risk assessment activity, the purpose of the assessment should be clearly stated. For Listeria monocytogenes, the purpose of risk assessment may be providing...
article 2000
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Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author), van den Berg, H. (author)
Chemicals/CAS: Homocysteine, 454-28-4; Proteins; Pyridoxic Acid, 82-82-6; Pyridoxine, 65-23-6
article 1999
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Fay, R.M. (author), Feron, V.J. (author), TNO Voeding (author)
Regarding risk evaluation of complex mixtures, the Working Group discussed the following topics: evaluation of the mixture as a whole, fractionation of the mixture, identification of the 'top ten' chemicals, and composite standards. It was concluded that no standard methodology for hazard identification and risk assessment of complex mixtures...
article 1996
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Henschler, D. (author), Bolt, H.M. (author), Jonker, D. (author), Pieters, M.N. (author), Groten, J.P. (author), TNO Voeding (author)
Advancing our knowledge on the toxicology of combined exposures to chemicals and implementation of this knowledge in guidelines for health risk assessment of such combined exposures are necessities dictated by the simple fact that humans are continuously exposed to a multitude of chemicals. A prerequisite for successful research and fruitful...
article 1996
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Kal, H.B. (author), Barendsen, G.W. (author), van der Kogel, A.J. (author)
Chemicals/CAS: Oxygen, 7782-44-7; Radiation-Sensitizing Agents
article 1995
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Schaapveld, K. (author), Hirasing, R.A. (author), TNO Preventie en Gezondheid (author)
article 1993
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Banta, H.D. (author), Vondeling, H. (author), Instituut voor verouderings- en vaatziekten onderzoek TNO (author)
This paper considers the diffusion of the 10 cases presented in this issue. Most of the cases have diffused relatively slowly. This slow diffusion can be explained by a number of factors, including budgetary restraints, financial incentives, physician conservatism, and lack of appropriate training. A consistent thread in the cases is the...
article 1993
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Buitendijk, S.E. (author), Treffers, P.E. (author), TNO Preventie en Gezondheid (author)
article 1993
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Schaapveld, K. (author), Hirasing, R.A. (author), Gunning-Schepers, L.J. (author), TNO Preventie en Gezondheid (author)
In opdracht van het ministerie van Welzijn, Volksgezondheid en Cultuur heeft het Nederlands Instituut voor Praeventieve Gezondheidszorg (NIPG-TNO) de Preventiegids vervaardigd, met een overzicht van de Nederlandse preventieprogramma's.1 Deze gids is in eerste instantie bestemd voor een aantal beroepsgroepen in de eerstelijnsgezondheidszorg en...
article 1993
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Hirasing, R.A. (author), Schaapveld, K. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
article 1993
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van de Water, H.P.A. (author), Davidse, W. (author), Kastelein, M. (author), Bergsma, E.W. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
article 1992
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van de Water, H.P.A. (author), Bijleveld, C.C.J.H. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
Eind 1990 verschenen in dit tijdschrift twee artikelen over het aantal met HIV ge├»nfecteerden in Nederland. Hieruit bleek dat het aantal HIV-seropositieven lager lag dan eerder werd aangenomen, maar dat desondanks een stijgend aantal AIDS-pati├źnten verwacht mocht worden. In uitkomsten liepen de twee onderzoeken niet ver uiteen. Jager et al....
article 1992
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