Searched for: subject:"sex%5C+difference"
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Fiamoncini, J. (author), Yiorkas, A.M. (author), Gedrich, K. (author), Rundle, M. (author), Alsters, S.I. (author), Roeselers, G. (author), van den Broek, T.J. (author), Clavel, T. (author), Lagkouvardos, I. (author), Wopereis, S. (author), Frost, G. (author), van Ommen, B. (author), Blakemore, A.I. (author), Daniel, H. (author)
Bile acids (BA) are signaling molecules with a wide range of biological effects, also identified among the most responsive plasma metabolites in the postprandial state. We here describe this response to different dietary challenges and report on key determinants linked to its interindividual variability. Healthy men and women (n = 72, 62 ± 8 yr,...
article 2017
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Remoundou, K. (author), Brennan, M. (author), Sacchettini, G. (author), Panzone, L. (author), Butler-Ellis, M.C. (author), Capri, E. (author), Charistou, A. (author), Chaideftou, E. (author), Gerritsen-Ebben, M.G. (author), Machera, K. (author), Spanoghe, P. (author), Glass, R. (author), Marchis, A. (author), Doanngoc, K. (author), Hart, A. (author), Frewer, L.J. (author)
The EU Directive on the sustainable use of pesticides (EU128/2009/EC) requires European Member States to develop training activities targeting occupational exposure to pesticides, and communication material aimed at residents and bystanders. Risk perceptions, knowledge and attitudes associated with passive and occupational exposure to pesticide...
article 2015
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van de Langenberg, D. (author), Hoekstra, T. (author), Twisk, J.W.R. (author), van Wouwe, J.P. (author), Hirasing, R.A. (author), Renders, C.M. (author), de Kroon, M.L.A. (author)
Objectives To test the hypothesis that greater weight fluctuation between 2 and 6 years is associated with an increase in weight measures (such as body mass index [BMI]) and cardiometabolic risk in young adulthood. Study design Weight fluctuation (determined by BMI SD scores) was measured at least 3 times between the ages of 2 and 6 years in 166...
article 2015
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Schönbeck, Y. (author), van Dommelen, P. (author), Hirasing, R.A. (author), van Buuren, S. (author)
Objectives To study trends in height of Turkish and Moroccan immigrant children living in The Netherlands, to investigate the association between height and background characteristics in these children, and to calculate height-for-age-references data for these groups. Design Nationwide cross-sectional data collection from children aged 0 to 18...
article 2015
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Hendriksen, M.A.H. (author), Verkaik-Kloosterman, J. (author), Noort, M.W. (author), van Raaij, J.M.A. (author)
Background/objectives: Sodium intake in the Netherlands is substantially above the recommended intake of 2400 mg/day. This study aimed to estimate the effect of two sodium reduction strategies, that is, modification of the composition of industrially processed foods toward the technologically feasible minimum level or alteration of consumers’...
article 2015
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Souverein, O.W. (author), de Vries, J.H.M. (author), Freese, R. (author), Watzl, B. (author), Bub, A. (author), III Miller, E.R., (author), Castenmiller, J.J.M. (author), Pasman, W.J. (author), van het Hof, K. (author), Chopra, M. (author), Karlsen, A. (author), Dragsted, L.O. (author), Winkels, R. (author), Itsiopoulos, C. (author), Brazionis, L. (author), O'Dea, K. (author), van Loo-Bouwman, C.A. (author), Naber, T.H.J. (author), van der Voet, H. (author), Boshuizen, H.C. (author)
Fruit and vegetable consumption produces changes in several biomarkers in blood. The present study aimed to examine the dose-response curve between fruit and vegetable consumption and carotenoid (alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, lutein and zeaxanthin), folate and vitamin C concentrations. Furthermore, a prediction...
article 2015
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Guigas, B. (author), de Leeuw van Weenen, J.E. (author), van Leeuwen, N. (author), Simonis-Bik, A.M. (author), van Haeften, T.W. (author), Nijpels, G. (author), Houwing-Duistermaat, J.J. (author), Beekman, M. (author), Deelen, J. (author), Havekes, L.M. (author), Penninx, B.W.J.H. (author), Vogelzangs, N. (author), van 't Riet, E. (author), Dehghan, A. (author), Hofman, A. (author), Witteman, J.C. (author), Uitterlinden, A.G. (author), Grarup, N. (author), Jørgensen, T. (author), Witte, D.R. (author), Lauritzen, T. (author), Hansen, T. (author), Pedersen, O. (author), Hottenga, J. (author), Romijn, J.A. (author), Diamant, M. (author), Kramer, M.H.H. (author), Heine, R.J. (author), Willemsen, G. (author), Dekker, J.M. (author), Eekhoff, E.M. (author), Pijl, H. (author), de Geus, E.J. (author), Slagboom, P.E. (author), 't Hart, L.M. (author)
Aims: Modulation of dopamine receptor D2 (DRD2) activity affects insulin secretion in both rodents and isolated pancreatic β-cells. We hypothesized that single nucleotide polymorphisms in the DRD2/ANKK1 locus may affect susceptibility to Type 2 diabetes in humans. Methods: Four potentially functional variants in the coding region of the DRD2...
article 2014
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Joosten, M.M. (author), Schrieks, I.C. (author), Hendriks, H.F.J. (author)
Background: Fetuin-A, a liver-derived glycoprotein that impairs insulin-signalling, has emerged as a biomarker for diabetes risk. Although moderate alcohol consumption has been inversely associated with fetuin-A, data from clinical trials are lacking. Thus, we evaluated whether moderate alcohol consumption decreases circulating levels of fetuin...
article 2014
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van Deemter, M. (author), Ponsioen, T.L. (author), Bank, R.A. (author), Snabel, J.M.M. (author), van der Worp, R.J. (author), Hooymans, J.M.M. (author), Los, L.I. (author), TNO Kwaliteit van Leven (author)
The human vitreous body undergoes structural changes with aging. This can be followed by a posterior vitreous detachment, which can result in ocular pathology. As in many collagenous tissues, age-related changes in the vitreous could be caused by the formation of advanced glycation end products (AGEs). The goal of this study was to find out...
article 2009
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Weisglas-Kuperus, N. (author), Hille, E.T.M. (author), Duivenvoorden, H.J. (author), Finken, M.J.J. (author), Wit, J.M. (author), van Buuren, S. (author), van Goudoever, J.B. (author), Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)
Objective: To examine the effect of intrauterine and neonatal growth, prematurity and personal and environmental risk factors on intelligence in adulthood in survivors of the early neonatal intensive care era. Methods: A large geographically based cohort comprised 94% of all babies born alive in the Netherlands in 1983 with a gestational age...
article 2009
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van Dijk, C.E. (author), de Boer, M.R. (author), Koppes, L.L.J. (author), Roos, J.C. (author), Lips, P. (author), Twisk, J.W.R. (author), TNO Kwaliteit van Leven (author)
Introduction: Studies on the association of vitamin D and bone mineral density (BMD) in adolescence and young adults have shown contrasting results. None of these studies have examined the course and baseline in vitamin D intake. The purpose of this study was to examine the association between baseline and the course of dietary vitamin D intake...
article 2009
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Hogervorst, J.G.F. (author), Schouten, L.J. (author), Konings, E.J.M. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
Background : Acrylamide is a probable human carcinogen that is present in several heat-treated foods. In epidemiological studies, positive associations between dietary acrylamide intake and the risks of endometrial, ovarian, estrogen receptor-positive breast, and renal cell cancers have been observed. The association between dietary acrylamide...
article 2009
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Bongaerts, B.W.C. (author), van den Brandt, P.A. (author), Goldbohm, R.A. (author), de Goeij, A.F.P.M. (author), Weijenberg, M.P. (author), TNO Kwaliteit van Leven (author)
Within the Netherlands Cohort Study on diet and cancer, we investigated associations between total alcohol consumption, specific alcoholic beverage consumption and risk of colorectal cancer (CRC) according to anatomical subsite. Hazard Ratios (HR) and 95% confidence intervals (CI) were estimated using Cox proportional hazards models. Analyses...
article 2008
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de Vogel, S. (author), Bongaerts, B.W.C. (author), Wouters, K.A.D. (author), Kester, A.D.M. (author), Schouten, L.J. (author), de Goeij, A.F.P.M. (author), de Bruïne, A.P. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), van Engeland, M. (author), Weijenberg, M.P. (author), TNO Kwaliteit van Leven (author)
Intake of dietary factors that serve as methyl group donors may influence promoter hypermethylation in colorectal carcinogenesis. We investigated whether dietary folate, vitamin B2 and vitamin B6, methionine and alcohol were associated with mutL homologue 1 (MLH1) hypermethylation and the related molecular phenotypes of MLH1 protein expression,...
article 2008
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Alizadeh Dehnavi, R. (author), Beishuizen, E.D. (author), van de Ree, M.A. (author), Le Cessie, S. (author), Huisman, M.V. (author), Kluft, C. (author), Princen, H.M.G. (author), Tamsma, J.T. (author), TNO Kwaliteit van Leven (author)
Background: The burden of cardiovascular disease in diabetes mellitus type 2 (DM2) patients is variable. We hypothesize that metabolic syndrome (MS) and low-grade systemic inflammation modify the extent of atherosclerosis in DM2. Methods: Vascular phenotype was determined using the following endothelium-related, hemostatic, and sonographic...
article 2008
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Kleemann, R. (author), Zadelaar, A.S.M. (author), Kooistra, T. (author), Gaubius Instituut TNO (author)
In the past few years, inflammation has emerged as a major driving force of atherosclerotic lesion development. It is now well-established that from early lesion to vulnerable plaque formation, numerous cellular and molecular inflammatory components participate in the disease process. The most prominent cells that invade in evolving lesions are...
article 2008
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Eijkemans, M. (author), Mommers, M. (author), de Vries, S.I. (author), van Buuren, S. (author), Stafleu, A. (author), Bakker, I. (author), Thijs, C. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE. Prevalence of asthma and overweight has increased simultaneously during the past decades. Several studies have reported an association between these two health problems, but it is unclear whether this relation is causal. We hypothesize that children with asthmatic symptoms are less physically active, which may contribute to the...
article 2008
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Hille, E.T.M. (author), Dorrepaal, C. (author), Perenboom, R. (author), Gravenhorst, J.B. (author), Brand, R. (author), Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)
Objective: To assess social lifestyle, risk-taking behavior, and psychopathology in young adults born very preterm or with a very low birthweight. Study design: This study was part of the 19-year follow-up in a large ongoing collaborative study in the Netherlands (the POPS study) on the long-term outcome of prematurity and dysmaturity. 656...
article 2008
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van Uffelen, J.G.Z. (author), Chinapaw, M.J.M. (author), van Mechelen, W. (author), Hopman-Rock, M. (author), TNO Kwaliteit van Leven (author)
Objective: To examine the effects of aerobic exercise or vitamin B supplementation on cognitive function in older adults with mild cognitive impairment (MCI). Design: Randomised placebo-controlled trial. Setting: General community. Participants: Community-dwelling adults aged 70-80 with MCI. Interventions : The 152 participants were randomly...
article 2008
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Männistö, S. (author), Yaun, S.S. (author), Hunter, D.J. (author), Spiegelman, D. (author), Adami, H.O. (author), Albanes, D. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Cerhan, J.R. (author), Colditz, G.A. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Harnack, L. (author), Leitzmann, M. (author), McCullough, M.L. (author), Miller, A.B. (author), Rohan, T.E. (author), Schatzkin, A. (author), Virtamo, J. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)
Dietary carotenoids have been hypothesized to protect against epithelial cancers. The authors analyzed the associations between intakes of specific carotenoids (alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein + zeaxanthin, and lycopene) and risk of colorectal cancer using the primary data from 11 cohort studies carried out in North...
article 2007
Searched for: subject:"sex%5C+difference"
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