Searched for: subject:"sensitization"
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Abokersh, M.H. (author), Spiekman, M.E. (author), Vijlbrief, O. (author), van Goch, T.A.J. (author), Vallies, M. (author), Boer, D. (author)
The nearly zero-energy buildings (nZEB) presents a promising contribution to fulfill the EU sustainable future targets. However, the construction industry that leads the development of nZEB is facing challenges to guarantee its performance. In this context, this paper proposes a methodology framework based on Multizone Resistance–Capacitance...
article 2021
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Leal Pérez, B.J. (author), Medrano Jiménez, J.A. (author), Bhardwaj, R. (author), Goetheer, E.L.V. (author), van Sint Annaland, M. (author), Gallucci, F. (author)
Nowadays, nearly 50% of the hydrogen produced worldwide comes from Steam Methane Reforming (SMR) at an environmental burden of 10.tCO2,eq/tH2 accelerating the consequences of global warming. One way to produce clean hydrogen is via methane pyrolysis using melts of metals and salts. Compared to SMR, significant less CO2 is produced due to...
article 2021
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Memelink, R.G. (author), Pasman, W.J. (author), Bongers, A. (author), Tump, A. (author), van Ginkel, A. (author), Tromp, W. (author), Wopereis, S. (author), Verlaan, S. (author), den Bosch, J.V.V. (author), Weijs, P.J.M. (author)
Background: Weight loss is key to treatment of older adults with obesity and type 2 diabetes, but also a risk for muscle mass loss. This study investigated whether a whey protein drink enriched with leucine and vitamin D could preserve muscle mass and improve glycemic control during combined lifestyle intervention in this population. Methods:...
article 2021
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Steen, M. (author)
In this essay, the author reflects on several personal experiences in projects and advocates Slow Innovation as an alternative to the putative need for speed, the primacy of efficiency and the assumption that faster is better. Yes, RI does take time. Let us wear Slow Innovation as a badge of honour. Let us promote reflexivity: make time for...
article 2021
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van Stijn, J.J. (author), Neerincx, M.A. (author), van Teije, A. (author), Vethman, S. (author)
Increasing automation in the healthcare sector calls for a Hybrid Intelligence (HI) approach to closely study and design the collaboration of humans and autonomous machines. Ensuring that medical HI systems' decision-making is ethical is key. The use of Team Design Patterns (TDPs) can advance this goal by describing successful and reusable...
conference paper 2021
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Smits, M. (author), Verhoeckx, K. (author), Knulst, A. (author), Welsing, P. (author), de Jong, A. (author), Houben, G.F. (author), Le, T.M. (author)
Predicting the allergenicity of novel proteins is challenging due to the absence of validated predictive methods and a well-defined reference set of proteins. The prevalence of sensitization could be a parameter to select reference proteins to characterize allergenic proteins. This study investigated whether the prevalence of sensitization of...
article 2021
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Kastelein, R.A. (author), Helder-Hoek, L. (author), Cornelisse, S.A. (author), von Benda-Beckmann, A.M. (author), Lam, F.P.A. (author), de Jong, C.A.F. (author), Ketten, D.R. (author)
Noise-induced temporary hearing threshold shift (TTS) was studied in a harbor porpoise exposed to impulsive sounds of scaled-down airguns while both stationary and free-swimming for up to 90 min. In a previous study, ∼4 dB TTS was elicited in this porpoise, but despite 8 dB higher single-shot and cumulative exposure levels (up to 199 dB re 1...
article 2020
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van Zoelen, E.M. (author), Cremers, A.H.M. (author), Dignum, F.P.M. (author), van Diggelen, J. (author), Peeters, M.M. (author)
Artificially intelligent agents increasingly collaborate with humans in human-agent teams. Timely proactive sharing of relevant information within the team contributes to the overall team performance. This paper presents a machine learning approach to proactive communication in AI-agents using contextual factors. Proactive communication was...
conference paper 2020
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Pasma, W. (author), Wesselink, E.M. (author), van Buuren, S. (author), de Graaff, J.C. (author), van Klei, W.A. (author)
Physiologic data from anesthesia monitors are automatically captured. Yet erroneous data are stored in the process as well. While this is not interfering with clinical care, research can be affected. Researchers should find ways to remove artifacts. The aim of the present study was to compare different artifact annotation strategies, and to...
article 2020
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Hayes, P. (author), van de Poel, I. (author), Steen, M. (author)
This article presents a conceptual investigation into the value impacts and relations of algorithms in the domain of justice and security. As a conceptual investigation, it represents one step in a value sensitive design based methodology (not incorporated here are empirical and technical investigations). Here, we explicate and analyse the...
article 2020
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Verhoeckx, K. (author), lindholm Bøgh, K. (author), Constable, A. (author), Epstein, M.M. (author), hoffmann Sommergruber, K. (author), Holzhauser, T. (author), Houben, G. (author), Kuehn, A. (author), Roggen, E. (author), O'Mahony, L. (author), Remington, B. (author), Crevel, R. (author)
The growing world population and increased pressure on agricultural resources are driving a shortage of dietary protein sources. As a result, industry is developing more sustainable novel food protein sources such as insects, algae and duckweed and using new processing techniques. Consumer exposure to these novel or processed proteins, could...
article 2020
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Kumar, P. (author), Sanderse, B. (author), Boorsma, K. (author), Caboni, M. (author)
A framework is presented for performing global sensitivity analysis of model parameters associated with the Blade Element Momentum (BEM) models. Sobol indices based on adaptive sparse polynomial expansions are used as a measure of global sensitivities. The sensitivity analysis workflow is developed using the uncertainty quantification toolbox...
conference paper 2020
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van Esch, B.C.A.M. (author), van Bilsen, J.H.M. (author), Gros- van Hest, M. (author), Kleinjans, L. (author), Belzer, C. (author), Jeurink, P.V. (author), Garssen, J. (author), Smit, J.J. (author), Pieters, R.H.H. (author), Knippels, L.M. (author)
Introduction This 4-center study is part of a project to validate a food allergy murine model for safety testing of hydrolyzed infant formulas. Aim The aim of the current multi-center experiment was to evaluate the residual allergenicity of three partial hydrolyzed whey proteins (pWH) in a multiple-parameter cow’s milk allergy murine model and...
article 2020
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van den Dries, M.A. (author), Guxens, M. (author), Spaan, S. (author), Ferguson, K.K. (author), Philips, E. (author), Santos, S. (author), Jaddoe, V.W.V. (author), Ghassabian, A. (author), Trasande, L. (author), Tiemeier, H. (author), Pronk, A. (author)
BACKGROUND: Prenatal exposures to phthalates and bisphenols are associated with impaired brain development in animals. However, epidemiological studies investigating the association between prenatal phthalate or bisphenol exposure and cognition have produced mixed findings and mostly had modest sample sizes and measured the exposure during the...
article 2020
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Verhoeckx, K. (author), Bogh, K.L. (author), Dupont, D. (author), Egger, L. (author), Gadermaier, G. (author), Larre, C. (author), Mackie, A. (author), Menard, O. (author), Adel-Patient, K. (author), Picariello, G. (author), Portmann, R. (author), Smit, J. (author), Turner, P. (author), Untersmayr, E. (author), Epstein, M.M. (author)
The current allergenicity assessment of novel proteins is based on the EFSA GMO guidance. Recently, EFSA launched a new guidance document on allergenicity assessment of GM plants (2017). This document describes, amongst other topics, the new scientific and regulatory developments on in vitro protein digestibility tests. The EFSA GMO Panel stated...
article 2019
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Nair, V. (author), Litjens, R. (author), Zhang, H. (author)
A suitability assessment and performance optimisation is presented of narrowband Internet of Things (NB-IoT) cellular technology for use in smart energy distribution networks. The focus is on the reliable and timely delivery of outage restoration and management (ORM) messages at the event of a local or regional power outage. Both the cellular NB...
article 2019
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Vijn, A.R.P.J. (author), Lepelaars, E.S.A.M. (author), Dubbeldam, J. (author), van Gijzen, M. (author), Heemink, A. (author)
This paper presents a parameter estimation method to determine the linear behavior of an object constructed of thin plates. Based on the magnetostatic field equations, an integral equation is derived that fully determines the induced magnetization, whenever the spatial magnetic susceptibility distribution is known. This forward problem is used...
article 2019
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Tsoy, N. (author), Prado, V. (author), Wypkema, A.W. (author), Quist, J. (author), Mourad, M. (author)
Environmental analysis should be performed early in the Research and Development (R&D) phases of new technologies to timely determine potential impact and, thereby, include prevention and minimization of unfavorable ecological impact into the innovation process. Here, we demonstrate the application of anticipatory Life Cycle Assessment (LCA) on...
article 2019
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Westerhout, J. (author), Krone, T. (author), Snippe, A. (author), Babé, L. (author), McClain, S.U. (author), Ladics, G.S. (author), Houben, G.G. (author), Verhoeckx, K.C. (author)
Alternative and sustainable protein sources (e.g., algae, duckweed, insects) are required to produce (future) foods. However, introduction of new food sources to the market requires a thorough risk assessment of nutritional, microbial and toxicological risks and potential allergic responses. Yet, the risk assessment of allergenic potential of...
article 2019
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de Koning, M.C. (author), Peterson, G.W. (author), van Grol, M. (author), Iordanov, I. (author), McEntee, M. (author)
Nerve agents are among the most toxic substances known to man. Recent events in Syria, Malaysia, and the UK illustrate that the threat of these substances is real and actual. The timely detection and identification of nerve agents is of great importance to facilitate timely decontamination or medical countermeasures. In this work, an effective...
article 2019
Searched for: subject:"sensitization"
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