Searched for: subject%3A%22screening%255C%2Btest%22
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Stalman, S.E. (author), Hellinga, I. (author), van Dommelen, P. (author), Hennekam, R.C.M. (author), Saari, A. (author), Sankilampi, U. (author), Dunkel, L. (author), Wit, J.M. (author), Kamp, G.A. (author), Plötz, F.B. (author)
Aims: To evaluate three guidelines for selecting short children for diagnostic workup in a general pediatric clinic. Methods: All patients (n = 131) aged 3.00-9.99 years who were referred for growth failure to a general pediatric clinic were evaluated for their medical history and growth and examined. All of them underwent the same standardized...
article 2015
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Vernooij-van Langen, A.M.M. (author), van der Pal, S.M. (author), Reijntjens, A.J.T. (author), Loeber, J.G. (author), Dompeling, E. (author), Dankert-Roelse, J.E. (author)
Background: False-positive screening results in newborn screening for cystic fibrosis may lead to parental stress, family relationship problems and a changed perception of the child's health. Aim of the study: To evaluate whether parental anxiety induced by a false positive screening result disappears after six months and to assess whether a...
article 2014
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van der Ploeg, C.P.B. (author), Lanting, C.I. (author), Verkerk, P.H. (author), TNO Kwaliteit van Leven (author)
article 2008
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Damveld, R.A. (author), Franken, A. (author), Arentshorst, M. (author), Punt, P.J. (author), Klis, F.M. (author), van den Hondel, C.A.M.J.J. (author), Ram, A.F.J. (author), TNO Kwaliteit van Leven (author)
To identify cell wall biosynthetic genes in filamentous fungi and thus potential targets for the discovery of new antifungals, we developed a novel screening method for cell wall mutants. It is based on our earlier observation that the Aspergillus niger agsA gene, which encodes a putative a-glucan synthase, is strongly induced in response to...
article 2008
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van der Ploeg, C.P.B. (author), Lanting, C.I. (author), de Kauffman-Boer, M.A. (author), Uilenburg, N.N. (author), de Ridder-Sluiter, J.G. (author), Verkerk, P.H. (author), TNO Kwaliteit van Leven (author), KvL (author)
Objective: To investigate whether false-positive outcomes on neonatal hearing screening cause long-lasting parental concerns. Methods: A general population of parents whose children had participated in the universal neonatal hearing screening (UNHS) programme were examined. Parents filled out a questionnaire 6 months after UNHS. Outcomes were...
article 2008
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van Buuren, S. (author), TNO Kwaliteit van Leven (author)
The standard deviation score (SDS) is a powerful tool for screening for growth-related problems. However, referral rules of the type 'if SDS(Y)<d, then refer' (for some constant d) are not optimal for answering the question: 'Does this child with measurement Y belong to the reference or to the diseased population?'. If the growth standard for...
article 2008
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TNO Kwaliteit van Leven (author), van Dommelen, P. (author), Grote, F.K. (author), Oostdijk, W. (author), Muinck Keizer de, (author), Schrama, S.M.P.F. (author), Boersma, B. (author), Damen, G.M. (author), Csizmadia, C.G. (author), Verkerk, P.H. (author), Wit, J.M. (author), van Buuren, S. (author)
Background: It is generally assumed that most patients with celiac disease (CD) have a slowed growth in terms of length (or height) and weight. However, the effectiveness of slowed growth as a tool for identifying children with CD is unknown. Our aim is to study the diagnostic efficiency of several growth criteria used to detect CD children....
article 2008
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Einhorn, R. (author), van Eekhof, J.A.H. (author), Engelberts, A.C. (author), Groeneveld, Y. (author), Verkerk, P.H. (author), Wit, J.M. (author), TNO Kwaliteit van Leven (author)
Background: In the Netherlands, preventive child health service (CHS) screening plays an important role in the early detection of congenital, developmental, physical, and mental disorders. Objective: To obtain insight into the referral patterns of children from CHS to general practitioners and from general practitioners to medical specialists....
article 2007
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Boerboom, A.M.J.F. (author), Vermeulen, M. (author), van der Woude, H. (author), Bremer, B.I. (author), Lee-Hilz, Y.Y. (author), Kampman, E. (author), van Bladeren, P.J. (author), Rietjens, I.M.C.M. (author), Aarts, J.M.M.J.G. (author), TNO Kwaliteit van Leven (author)
The electrophile-responsive element (EpRE) is a transcriptional enhancer involved in cancer-chemoprotective gene expression modulation by certain food components. Two stably transfected luciferase reporter cell lines were developed, EpRE(hNQO1)-LUX and EpRE(mGST-Ya)-LUX, based on EpRE sequences from the human NAD(P)H:quinone oxidoreductase ...
article 2006
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Männistö, S. (author), Dixon, L.B. (author), Balder, H.F. (author), Virtanen, M.J. (author), Krogh, V. (author), Khani, B.R. (author), Berrino, F. (author), van den Brandt, P.A. (author), Hartman, A.M. (author), Pietinen, P. (author), Tan, F. (author), Wolk, A. (author), Goldbohm, R.A. (author), TNO Kwaliteit van Leven TNO Voeding (author)
Objective: Only a few consistent findings on individual foods or nutrients that influence breast cancer risk have emerged thus far. Since people do not consume individual foods but certain combinations of them, the analysis of dietary patterns may offer an additional aspect for assessing associations between diet and diseases such as breast...
article 2005
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van Dommelen, P. (author), van Buuren, S. (author), Zandwijken, G.R.J. (author), Verkerk, P.H. (author), TNO Kwaliteit van Leven (author)
The goal of this study is to assess whether a growth curve model approach will lead to a more precise detection of Turner sydnrome (TS) than conventional referral criteria for growth monitoring. The Jenss-Bayley growth curve model was used to describe the process of growth over time. A new screening rule is defined on the parameters of this...
article 2005
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de Croon, E.M. (author), Blonk, R.W. (author), Sluiter, J.K. (author), Frings-Dresen, M.H. (author), TNO Kwaliteit van Leven (author)
Background: Monitoring psychological job strain may help occupational physicians to take preventive action at the appropriate time. For this purpose, the 10-item trucker strain monitor (TSM) assessing work-related fatigue and sleeping problems in truck drivers was developed. Objectives: This study examined (1) test-retest reliability, (2)...
article 2005
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Grote, F.K. (author), Oostdijk, W. (author), de Muinck Keizer-Schrama, S.M.P.F. (author), Dekker, F.W. (author), Verkerk, P.H. (author), Wit, J.M. (author), TNO Kwaliteit van Leven (author), KvL (author)
Background/Aims: Growth monitoring is almost universally performed, but few data are available on which referral criteria and diagnostic work-up are used worldwide for children with short stature. Methods: A short questionnaire, containing questions on auxological screening and on diagnostic criteria for short stature, was sent to all members of...
article 2005
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de Brabander, H.F. (author), Poelmans, S. (author), Schilt, R. (author), Stephany, R.W. (author), le Bizec, B. (author), Draisci, R. (author), Sterk, S.S. (author), van Ginkel, L.A. (author), Courtheyn, D. (author), van Hoof, N. (author), Macrì, A. (author), de Wasch, K. (author), TNO Voeding (author)
The review summarizes current knowledge on the possible illegal use of the anabolic steroid boldenone. The presence of boldenone and metabolites in different animal species and the possibility of the occurrence of endogenous boldenone and metabolites is assessed, as are the methods of analysis used for detection. Different laboratories in the...
article 2004
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Knippels, L.M.J. (author), van Wijk, F. (author), Penninks, A.H. (author), TNO Voeding (author)
Purpose of review This review summarizes selected articles on animal models of food allergy published in 2003. The research areas that are covered include mechanistic studies, the search for new therapies, as well as screening models for hazard identification of potential allergens. Recent findings Novel treatment options of both prevention and...
article 2004
document
Germolec, D.R. (author), Kashon, M. (author), Nyska, A. (author), Kuper, C.F. (author), Portier, C. (author), Kommineni, C. (author), Johnson, K.A. (author), Luster, M.I. (author), TNO Voeding (author)
The accuracy of extended histopathology to detect immunotoxic chemicals in female B6C3F1 mice was evaluated under the auspices of the National Toxicology Program (NTP). A workgroup was formed consisting of four pathologists who conducted extended histopathological evaluation of lymphoid tissues obtained from a subset of NTP toxicology studies,...
article 2004
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Rennen, M.A.J. (author), Bouwman, T. (author), Wilschut, A. (author), Bessems, J.G.M. (author), de Heer, C. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)
Due to a lack of route-specific toxicity data, the health risks resulting from occupational exposure are frequently assessed by route-to-route (RtR) extrapolation based on oral toxicity data. Insight into the conditions for and the uncertainties connected with the application of RtR extrapolation has not been clearly described in a systematic...
article 2004
document
Germolec, D.R. (author), Nyska, A. (author), Kashon, M. (author), Kuper, C.F. (author), Portier, C. (author), Kommineni, C. (author), Johnson, K.A. (author), Luster, M.I. (author), TNO Voeding (author)
There has been considerable interest in the use of expanded histopathology as a primary screen for immunotoxicity assessment. To determine the utility of a semiquantitative histopathology approach for examining specific structural and architectural changes in lymphoid tissues, a validation effort was initiated. This study addresses the...
article 2004
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Kralj, S. (author), Geel van - Schutten, G.H. (author), van der Maarel, M.J.E.C. (author), Dijkhuizen, L. (author)
Limited information is available about homopolysaccharide synthesis in the genus Lactobacillus. Using efficient screening techniques, extracellular glucosyltransferase (GTF) enzyme activity, resulting in α-glucan synthesis from sucrose, was detected in various lactobacilli. PCR with degenerate primers based on homologous boxes of known...
article 2003
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van Straaten, H.L.M. (author), Hille, E.T.M. (author), Kok, J.H. (author), Verkerk, P.H. (author), Baerts, W. (author), Bunkers, C.M. (author), Smink, E.W.A. (author), van Elburg, R.M. (author), de Kleine, M.J.K. (author), Ilsen, A. (author), Maingay-Visser, A.P.G.F. (author), de Vries, L.S. (author), Weisglas-Kuperus, N. (author)
Aim: As part of a future national neonatal hearing screening programme in the Netherlands, automated auditory brainstem response (AABR) hearing screening was implemented in seven neonatal intensive care units (NICUs). The objective was to evaluate key outcomes of this programme: participation rate, first stage success rate, pass/referral rates,...
article 2003
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