Searched for: subject%3A%22risk%255C%2Bfactor%22
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Teune, M.J. (author), van Wassenaer, A.G. (author), van Dommelen, P. (author), Mol, B.W.J. (author), Opmeer, B.C. (author)
Objective: Many obstetric interventions are performed to improve long-term neonatal outcome. However, long-term neonatal outcome is usually not a primary outcome because it is time-consuming and expensive. The aim of this project was to identify different perinatal risk indicators and to develop prediction models for neurologic morbidity at 2...
article 2011
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Preller, L. (author), van den Bosch, L.M.C. (author), van den Brandt, P.A. (author), Kauppinen, T. (author), Goldbohm, R.A. (author), TNO Kwaliteit van Leven (author)
Objectives: The lung cancer carcinogenicity of crystalline silica dust remains the subject of discussion. Epidemiological evidence is based on occupational cohort studies and population-based case-control studies. The aim of this study was to assess associations between male lung cancer risk and silica exposure in a population-based cohort study...
article 2010
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de Vries-van der Weij, J. (author), Toet, K. (author), Zadelaar, A.S.M. (author), Wielinga, P.Y. (author), Kleemann, R. (author), Rensen, P.C.N. (author), Kooistra, T. (author), TNO Kwaliteit van Leven (author)
Objective: Inflammation plays an important role in all stages of atherosclerosis, but little is known about the therapeutic effects of quenching inflammation in already existing atherosclerotic lesions. Putative beneficial effects of salicylate, an inhibitor of NF-κB activation, were studied in mice with established lesions. Methods: ApoE*3...
article 2010
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Smits, K.M. (author), Schouten, L.J. (author), Hudak, E. (author), Verhage, B. (author), van Dijk, B.A.C. (author), van de Hulsbergen - Kaa, C.A. (author), Goldbohm, R.A. (author), Oosterwijk, E. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
Purpose: Body mass index (BMI) is an important risk factor for clear-cell renal cancer (cc-RCC). A common molecular alteration in cc-RCC is loss-of-function of the von Hippel-Lindau (VHL) gene. We evaluated the association between BMI and VHL mutations in cc-RCC by using data from the Netherlands Cohort Study (NLCS), a prospective study, which...
article 2010
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Vogel, L. (author), Verschuure, H. (author), van der Ploeg, C.P.B. (author), Brug, J. (author), Raat, H. (author), TNO Kwaliteit van Leven (author)
Objectives. We estimated whether and to what extent a group of adolescents were at risk of developing permanent hearing loss as a result of voluntary exposure to high-volume music, and we assessed whether such exposure was associated with hearing-related symptoms. Methods. In 2007, 1512 adolescents (aged 12-19 years) in Dutch secondary schools...
article 2010
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Ceconi, C. (author), Fox, K.M. (author), Remme, W.J. (author), Simoons, M.L. (author), Deckers, J.W. (author), Bertrand, M. (author), Parrinello, G. (author), Kluft, C. (author), Blann, A. (author), Cokkinos, D. (author), Ferrari, R. (author), TNO Kwaliteit van Leven (author)
The PERTINENT study measured biomarkers of atherosclerosis and thrombosis in a stable coronary artery disease population from EUROPA receiving ACE inhibition with perindopril 8 mg/day or placebo. Biomarkers of inflammation, C-reactive protein (CRP), fibrinogen, and tumor necrosis factor-alpha (TNF-α), and a biomarker of thrombosis, d-dimer, were...
article 2009
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Schuller, A.A. (author), Bruers, J.J. (author), van Dam, B.A. (author), Poorterman, J.H. (author), Gerardu, V.A. (author), Truin, G.J. (author), TNO Kwaliteit van Leven (author)
In 2007 a study was undertaken of the restorative care index of the teeth of children under the age of 18. The aim of this study was to gain insight into the factors associated with the restorative care index in children. Factors investigated were (post-) brushing, inspection frequency, sweets-consumption frequency, socio-economic status and...
article 2009
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Vogel, I. (author), Brug, J. (author), van der Ploeg, C.P.B. (author), Raat, H. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE. To identify parties involved in the prevention of MP3-induced hearing loss among adolescents and potentially effective prevention strategies and interventions. METHODS. Thirty experts in fields such as scientific research, medical practice, community health professions, education, youth work, music entertainment, and enforcement...
article 2009
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Zwart, J.J. (author), Richters, J.M. (author), Öry, F. (author), de Vries, J.I.P. (author), Bloemenkamp, K.W.M. (author), van Roosmalen, J. (author)
Objective: To assess incidence of uterine rupture in scarred and unscarred uteri and its maternal and fetal complications in a nationwide design. Design: Population-based cohort study. Setting: All 98 maternity units in the Netherlands. Population: All women delivering in the Netherlands between August 2004 and August 2006 (n = 371 021). Methods...
article 2009
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Keszei, A.P. (author), Verhage, B.A.J. (author), Heinen, M.M. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
An association between high intake of folate and reduced risk of cancer has been suggested by previous research. However, epidemiologic data from cohort studies regarding the relationship between dietary folate and pancreatic cancer are sparse and inconsistent. We examined the association between dietary folate intake and risk of pancreatic...
article 2009
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Vogel, I. (author), Verschuure, H. (author), van der Ploeg, C.P.B. (author), Brug, J. (author), Raat, H. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE. The goal was to assess risky and protective listening behaviors of adolescent users of MP3 players and the association of these behaviors with demographic characteristics and frequency of use. METHODS. In 2007, 1687 adolescents (12-19 years of age) in 68 classes in 15 Dutch secondary schools were invited to complete questionnaires...
article 2009
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Hellgren, M. (author), Conard, J. (author), Norris, L. (author), Kluft, C. (author), TNO Kwaliteit van Leven (author)
Objective: To study cardiovascular risk markers in women taking estradiol/trimegestone or estradiol/dydrogesterone. Design: Multicenter, randomized, prospective, double-blind study of 184 healthy post-menopausal women randomized to 6 cycles of either estradiol (2 mg) + trimegestone (0.5 mg) (T-group) or estradiol (2 mg) + dydrogesterone (10 mg) ...
article 2009
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Nepveu, M. (author), Yavuz, F. (author), David, P. (author), TNO Bouw en Ondergrond (author)
Uncertainties related with underground CO2 storage play a vital role in risk assessment with respect to Carbon storage and capture projects (CCS). The main purpose of risk assessment is to determine a qualitative and quantitative picture of hazardous processes or events. One makes a comprehensive inventory of risk factors, and stores the results...
article 2009
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Weisglas-Kuperus, N. (author), Hille, E.T.M. (author), Duivenvoorden, H.J. (author), Finken, M.J.J. (author), Wit, J.M. (author), van Buuren, S. (author), van Goudoever, J.B. (author), Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)
Objective: To examine the effect of intrauterine and neonatal growth, prematurity and personal and environmental risk factors on intelligence in adulthood in survivors of the early neonatal intensive care era. Methods: A large geographically based cohort comprised 94% of all babies born alive in the Netherlands in 1983 with a gestational age...
article 2009
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Zwart, J.J. (author), Richters, J.M. (author), Öry, F. (author), de Vries, J.I.P. (author), Bloemenkamp, K.W.M. (author), van Roosmalen, J. (author), TNO Kwaliteit van Leven (author)
article 2009
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Heinen, M.M. (author), Verhage, B.A.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
Meat contains numerous carcinogens, such as heterocyclic amines, polycyclic aromatic hydrocarbons, and N-nitroso compounds, which can be derived either from natural food or during the process of food preparation. These carcinogens may increase pancreatic cancer risk. Furthermore, studies in animals showed that polyunsaturated fatty acids,...
article 2009
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Hogervorst, J.G.F. (author), Schouten, L.J. (author), Konings, E.J.M. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
Background : Acrylamide is a probable human carcinogen that is present in several heat-treated foods. In epidemiological studies, positive associations between dietary acrylamide intake and the risks of endometrial, ovarian, estrogen receptor-positive breast, and renal cell cancers have been observed. The association between dietary acrylamide...
article 2009
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Hellebrekers, B.W.J. (author), Trimbos-Kemper, T.C.M. (author), Boesten, L. (author), Jansen, F.W. (author), Kolkman, W. (author), Trimbos, J.B. (author), Press, R.R. (author), van Poelgeest, M.I.E. (author), Emeis, S.J. (author), Kooistra, T. (author), TNO Kwaliteit van Leven (author)
Objective: To identify predictors of postsurgical adhesion formation in peritoneal fluid and plasma, and assess efficacy and safety of reteplase (recombinant plasminogen activator [r-PA]). Design: Prospective randomized study. Setting: University Medical Center. Patient(s): Twenty-six abdominal myomectomy patients with early second-look...
article 2009
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Baatjies, R. (author), Lopata, A.L. (author), Sander, I. (author), Raulf-Heimsoth, M. (author), Batemane, E.D. (author), Meijster, T. (author), Heederik, D. (author), Robins, T.G. (author), Jeebhay, M.F. (author), TNO Kwaliteit van Leven (author)
While baker's asthma has been well described, various asthma phenotypes in bakery workers have yet to be characterised. Our study aims to describe the asthma phenotypes in supermarket bakery workers in relation to host risk factors and self-reported exposure to flour dust. A cross-sectional study of 517 supermarket bakery workers in 31 bakeries...
article 2009
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Geert Heidema, A. (author), Thissen, U. (author), Boer, J.M.A. (author), Bouwman, F.G. (author), Feskens, E.J.M. (author), Mariman, E.C.M. (author), TNO Kwaliteit van Leven (author)
In this study, we applied the multivariate statistical tool Partial Least Squares (PLS) to analyze the relative importance of 83 plasma proteins in relation to coronary heart disease (CHD) mortality and the intermediate end points body mass index, HDL-cholesterol and total cholesterol. From a Dutch monitoring project for cardiovascular disease...
article 2009
Searched for: subject%3A%22risk%255C%2Bfactor%22
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