Searched for: subject%3A%22radiography%22
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de Lange-Brokaar, B.J.E. (author), Ioan-Facsinay, A. (author), Yusuf, E. (author), Visser, A.W. (author), Kroon, H.M. (author), van Osch, G.J.V.M. (author), Zuurmond, A.M. (author), Stojanovic-Susulic, V. (author), Bloem, J.L. (author), Nelissen, R.G.H.H. (author), Huizinga, T.W. (author), Kloppenburg, M. (author)
Objective To determine possible patterns of synovitis on contrast-enhanced magnetic resonance imaging (CE-MRI) and its relation to pain and severity in patients with radiographic knee osteoarthritis (OA). Methods In total, 86 patients (mean age 62 years, 66% women, median body mass index 29 kg/m2) with symptomatic knee OA (Kellgren/Lawrence...
article 2015
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Vos, P.A.J.M. (author), de Groot, J. (author), Huisman, A.M. (author), Oostveen, J.C.M. (author), Marijnissen, A.C.A. (author), Bijlsma, J.W.J. (author), van El, B. (author), Zuurmond, A.M. (author), Lafeber, F.P.J.G. (author), TNO Kwaliteit van Leven (author)
Objectives: Age-related changes in articular cartilage are likely to play a role in the aetiology of osteoarthritis (OA). One of the major age-related changes in cartilage is the accumulation of advanced-glycation-endproducts (AGEs). Since, cartilage tissue is not readily available from patients for studying AGE levels, alternative approaches...
article 2010
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Frost-Christensen, L.N. (author), Mastbergen, S.C. (author), Vianen, M.E. (author), Hartog, A. (author), de Groot, J. (author), Voorhout, G. (author), van Wees, A.M.C. (author), Lafeber, F.P.J.G. (author), Hazewinkel, H.A.W. (author), TNO Kwaliteit van Leven (author)
Objective: The most used model for joint instability is the canine anterior cruciate ligament transection (ACLT)-model. The ACLT-model can be extended with a medial meniscectomy (MX) (i.e., ACLT-MX-model) to avoid unintentional, and with that variable, meniscal damage. The present study compares the ACLT-MX-model with the more recently...
article 2008
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Hoogendoorn, R.J.W. (author), Helder, M.N. (author), Kroeze, R.J. (author), Bank, R.A. (author), Smit, T.H. (author), Wuisman, P.I.J.M. (author), TNO Kwaliteit van Leven (author)
STUDY DESIGN. Twelve goats were chemically degenerated and the development of the degenerative signs was followed for 26 weeks to evaluate the progression of the induced degeneration. The results were also compared with a previous study to determine the reproducibility. OBJECTIVES. The purpose of this study was determine whether this...
article 2008
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Ainola, M. (author), Valleala, H. (author), Nykänen, P. (author), Risteli, J. (author), Hanemaaijer, R. (author), Konttinen, Y.T. (author), TNO Kwaliteit van Leven (author)
Objective. The excellent poster painter Henri de Toulouse-Lautrec is the most famous patient with cathepsin K-deficient pycnodysostosis. Cathepsin K is believed to play a major role in osteoclast-driven bone resorption. In this study we explored the role of cathepsin K in bone resorption in a patient with a cathepsin K mutation causing...
article 2008
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TNO Defensie en Veiligheid (author), van der Meer, B.J. (author), Dijkstra, M.H. (author), Carton, E.P. (author)
Jacketed penetrators of mid calibre type have been produced by explosive cladding of various jackets on two different kinds of tungsten heavy alloy (WHA) rods. The jackets, of different thicknesses, were made of steel-37, stainless steel 316L, titanium grade (2, 3) and pure titanium grade 2. The jacket increased the flexural rigidity of the core...
conference paper 2008
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Meulenbelt, I. (author), Kloppenburg, M. (author), Kroon, H.M. (author), Houwing-Duistermaat, J.J. (author), Garnero, P. (author), Hellio-Le Graverand, M.-P. (author), de Groot, J. (author), Slagboom, P.E. (author), TNO Kwaliteit van Leven (author)
Objective: To assess the relationship of biochemical markers and radiographic signs of osteoarthritis (ROA) in the subjects with symptomatic osteoarthritis (OA) at multiple sites of the Genetics osteoARthritis and Progression (GARP) study. Methods: We have measured eight biochemical markers, representing tissue turnover of cartilage, bone,...
article 2007
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TNO Kwaliteit van Leven (author), Meulenbelt, I. (author), Kloppenburg, M. (author), Kroon, H.M. (author), Houwing-Duistermaat, J.J. (author), Garnero, P. (author), Hellio Le Graverand, M.P. (author), de Groot, J. (author), Slagboom, P.E. (author)
Objective: To assess the relation between the urinary concentrations of type II collagen C-telopeptide (UCTX-II) and radiographie signs of osteoarthritis (ROA) in the GARP (Genetics, Arthrosis and Progression) study. Methods: UCTX-II levels were measured in GARP study participants, who are sibling pairs predominantly with symptomatic...
article 2006
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Lamers, R.J.A.N. (author), van Nesselrooij, J.H.J. (author), Kraus, V.B. (author), Jordan, J.M. (author), Renner, J.B. (author), Dragomir, A.D. (author), Luta, G. (author), van der Greef, J. (author), de Groot, J. (author), TNO Kwaliteit van Leven (author)
Objective: Osteoarthritis (OA) is one of the most common diseases among the elderly. The main characteristic is the progressive destruction of articular cartilage. We lack quantitative and sensitive biomarkers for OA to detect changes in the joints in an early stage of the disease. In this study, we investigated whether a urinary metabolite...
article 2005
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TNO Kwaliteit van Leven TNO Voeding (author), Tjoe Nij, E. (author), Heederik, D. (author)
Objectives: The aim of this study was to assess the magnitude of the silicosis and cancer risk among construction workers. Methods: In 1998, 1335 of 4173 invited construction workers with expected high cumulative exposure to quartz were studied for early signs of silicosis. In 2002 the study was repeated for 96 persons. Exposure measurements...
article 2005
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Reekers, J.A. (author), Hoogeveen, Y.L. (author), Wijnands, M. (author), Bosma, G. (author), Mulder, R. (author), Oliva, V.L. (author), TNO Voeding (author)
PURPOSE: A new inferior vena cava filter was evaluated in vivo to determine the percutaneous retrievability after an implantation period of up to 18 days. MATERIALS AND METHODS: The inferior venae cavae of six goats were percutaneously implanted with three filters, and one animal received two filters. To assess filter stability, a plain...
article 2004
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TNO Preventie en Gezondheid (author), Landewé, R. (author), Geusens, P. (author), Boers, M. (author), van der Heijde, D. (author), Lems, W. (author), te Koppele, J. (author), van der Linden, S. (author), Garnero, P. (author)
Objective. To investigate in a randomized clinical trial setting with an aggressive combination-therapy arm and a mild-monotherapy arm, whether therapy-induced changes in urinary C-terminal crosslinking telopeptide of type I collagen (CTX-I) and type II collagen (CTX-II) predict 5-year radiographic progression in patients with rheumatoid...
article 2004
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Kalsbeek, H. (author), Poorterman, J.H. (author), Eijkman, M.A. (author), Verrips, G.H. (author)
In 1987, 1993 and 1999 an epidemiological study was performed on oral health in youngsters, aged 5, 11, 17 or 23 years, in whom oral health care was covered by a health insurance fund. The prevalence of caries in the deciduous teeth of the 5-year-olds (examined without radiographs) did not change significantly between 1987 and 1999. Only a small...
article 2002
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van der Laan, W. (author), Molenaar, E. (author), Ronday, K. (author), Verheijen, J. (author), Breedveld, F. (author), Greenwald, R. (author), Dijkmans, B. (author), Tekoppele, J. (author), Gaubius instituut TNO (author)
Objective. To investigate the effects of doxycycline on disease activity and joint destruction in patients with rheumatoid arthritis (RA). Methods. A 36 week double blind, placebo controlled crossover trial was conducted. Patients (n = 66) received 50 mg doxycycline or placebo twice a day during 12, 24, or 36 weeks. Patient assessments were...
article 2001
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Kemerink, G.J. (author), Kicken, P.J.H. (author), Schultz, F.W. (author), Zoetelief, J. (author), van Engelshoven, J.M.A. (author), Centrum voor Stralingsbescherming en Dosimetrie TNO (author)
This study aims at accurate quantification of x-ray exposure and effective dose to the patient in abdominal arteriography. Using an automatic monitoring system, all relevant exposure parameters were determined during 172 abdominal arteriographies. Common projections were extracted for a 'normal' reference group of procedures and used in Monte...
article 1999
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van Bree, J.L.M.J. (author), Lans, M. (author), Szymczak, M. (author), TNO Prins Maurits Laboratorium (author)
conference paper 1999
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van Bree, J.L.M.J. (author), Duvalois, W. (author), Somogy, P. (author), Prins Maurits Laboratorium TNO (author)
conference paper 1996
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TNO Preventie en Gezondheid (author), Vanderkerken, K. (author), Goes, E. (author), de Raeve, H. (author), Radl, J. (author), van Camp, B. (author)
The evolution of bone lesions in transplantable C57BL/KaLwRij 5T mouse myeloma (MM) has been followed in vivo. Mice were anaesthetised and a radiograph of the pelvis and hind legs was performed by a radiograph dedicated for mammography. This is the first description of an in vivo technique under experimental conditions whereby the development of...
article 1996
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Somogy, P. (author), van Bree, J.L.M.J. (author), Prins Maurits Laboratorium TNO (author)
conference paper 1995
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TNO Preventie en Gezondheid (author), Wenzel, A. (author), Pitts, N. (author), Verdonschot, E.H. (author), Kalsbeek, H. (author)
The developments that have been taking place in radiographic caries diagnosis, within the context of the changes occurring in both the disease process and the available technology, are reviewed. The decline in caries prevalence seen in many western countries has been accompanied by changes in the pattern and behaviour of lesions. More lesions...
article 1993
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