Pharmacokinetics and bioavailability of dapsone in the beagle dog

Chemicals/CAS: dapsone, 80-08-0

Excretion-retention data of steady state gas exchange in tidal breathing. I.Dependency on the blood-gas partition coefficient

Microdetermination of vitamin A in human plasma using high-performance liquid chromatography with fluorescence detection

Chemicals/CAS: n,n dimethylacetamide, 127-19-5; retinol, 68-26-8, 82445-97-4; Vitamin A, 11103-57-4

Pressure-diameter relationships of segments of human finger arteries

Pressure-diameter relationships of segments of human finger arteries, aged 57-85 years, were measured in vitro. The arteries, obtained at autopsy within 48 h after death, were stored in glucose-free Tyrode at 4 degrees C. Experiments began within 40 h after autopsy. The diameter responses to various transmural pressure changes, with and without...

Excretion-retention data of steady state gas exchange in tidal breathing. II. Dependency on the diffusion coefficient

Vehicle control during curve driving

Based on a preview-predictor model, the time-to-line crossing (TLC) description was developed to quantify the potential role of error-neglecting strategies in driving. In a previous study the usefulness of the TLC concept was illustrated for straight lane keeping. In the present analysis TLC was applied to describe steering through a curve. When...

Concentration-time mortality response relationship of irritant and systemically acting vapours and gases

This report presents the re-evaluation of the raw data of previously published acute inhalation toxicity studies of some volatile industrial chemicals. In these studies both concentration and exposure time were varied. The raw data were obtained from an extensive literature search and were subjected to probit analysis. The results show that the...

Determination of progesterone by liquid chromatography - mass spectrometry using a moving-belt interface and isotope dilution

Progesterone can be determined rapidly and accurately with the method presented, using isotope dilution LC-MS with a moving-belt interface. Deactivation is very useful in that it minimizes belt memory effects and optimizes belt desorption characteristics. Since the moving-belt properties were found to change during time with respect to the...

Determination of the B2 vitamer flavin-adenine dinucleotide in whole blood by high-performance liquid chromatography with fluorometric detection

A reliable high-performance liquid chromatographic (HPLC) method is developed for the analysis of FAD in whole blood of humans. The method is able to separate FAD, FMN and Rb from each other and from interfering compounds. A reliable and sensitive detection of FAD has been obtained by selecting the optimal pH of the mobile phase and optimal...

Anaerobic formation of alpha-hexachlorocyclohexane from gamma-hexachlorocyclohexane in soil and by Escherichia coli

In two soil types small amounts of ??-hexachlorocyclohexane were formed from ??-hexachlorocyclohexane under submerged conditions, but not under aerobic conditions. In the submerged soils ??-tetrachlorocyclohexene was detected as a major metabolite of ??-hexachlorocyclohexane, whereas aerobic soil incubation yielded ??-pentachlorocyclohexene....