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Hurst, R. (author), Collings, R. (author), Harvey, L.J. (author), King, M. (author), Hooper, L. (author), Bouwman, J. (author), Gurinovic, M. (author), Fairweather-Tait, S.J. (author)Current reference values for selenium, an essential micronutrient, are based on the intake of selenium that is required to achieve maximal glutathione peroxidase activity in plasma or erythrocytes. In order to assess the evidence of relevance to setting dietary reference values for selenium, the EURRECA Network of Excellence focused on...article 2013
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Radacsi, N. (author), van der Heijden, A.E.D.M. (author), Stankiewicz, A.I. (author), ter Horst, J.H. (author)In this study, atmospheric pressure cold plasma (surface dielectric barrier discharge) was used as an alternative energy form to intensify solution crystallization and produce nano-sized organic crystals. Nano-sized particles can have beneficial product properties such as improved internal quality and dissolution rate, compared to conventionally...article 2013
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Šimor, M. (author), Creyghton, Y. (author)Due to ongoing improvements in polymer-based materials, they are being used in an increasingly wider range of applications. In addition to special bulk physical properties, specific surface properties are often required in particular applications. However, common polymers very often do not possess the desired surface properties. Several...bookPart 2013
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Abadjieva, E. (author), van der Heijden, A.E.D.M. (author), Creyghton, Y.L.M. (author), van Ommen, J.R. (author)Fluorocarbon coatings have been deposited on micron-sized silica particles by means of atmospheric pressure plasma-enhanced chemical vapor deposition (PECVD). The silica particles have a diameter in the range between 40 and 70 ?m. They are fluidized at atmospheric pressure in a circulating fluidized bed combined with a dielectric barrier...article 2012
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Theelen, M.J. (author), Habets, D. (author), Staemmler, L. (author), Winands, H. (author), Bolt, P.J. (author)Organosilicon coatings provide good optical and mechanical properties and are excellent candidates for the modification of the surface energy of polymers. These coatings can be deposited by plasma polymerization of hexamethyldisiloxane (HMDSO) under atmospheric pressure and at room temperature. The resulting films can range from soft,...article 2012
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Lindenburg, P.W. (author), Tempels, F.W.A. (author), Tjaden, U.R. (author), van der Greef, J. (author), Hankemeier, T. (author)Electroextraction (EE) takes place in a two-phase liquid-liquid system, consisting of an aqueous and an organic phase, where an applied electric field causes ions to be extracted from one phase into the other, to be concentrated close after the liquid-liquid interface. The extraction takes place in a wide-bore capillary that is connected to a 2...article 2012
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Bayle, M.L. (author), Wopereis, S. (author), Bouwman, J. (author), van Ommen, B. (author), Scalbert, A. (author), Pujos-Guillot, E. (author)Recommended dietary allowances for micronutrients fluctuate noticeably within European Union countries. The Network of Excellence EURRECA (EURopean micronutrient RECommendations Aligned) aims at harmonising micronutrient intake recommendations through population groups. The lack of proper markers of status for some micronutrients limits progress...article 2012
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Radacsi, N. (author)Crystallization is one of the oldest separation and product formation techniques that continues to be in use today. Despite its long history, it only started to develop significantly in the past few decades. In this thesis, the application of Process Intensification in crystallization is investigated. Process Intensification is a set of often...doctoral thesis 2012
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Wopereis, S. (author), Radonjic, M. (author), Rubingh, C. (author), van Erk, M. (author), Smilde, A. (author), van Duyvenvoorde, W. (author), Cnubben, N. (author), Kooistra, T. (author), van Ommen, B. (author), Kleemann, R. (author)The prevalence of diabetes mellitus Type 2 could be significantly reduced by early identification of subjects at risk, allowing for better prevention and earlier treatment. Glucose intolerance (GI) is a hallmark of the prediabetic stage. This study aims at identifying 1) prognostic biomarkers predicting the risk of developing GI later in life...article 2012
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George, A. (author), Stawski, T.M. (author), Unnikrishnan, S. (author), Veldhuis, S.A. (author), ten Elshof, J.E. (author)A simple and cost effective methodology for large area micro and nanopatterning of a wide range of functional materials on flexible substrates is presented. A hydrophobic-hydrophilic chemical contrast was patterned on surfaces of various flexible plastic substrates using molds and shadow masks with which selected areas of the substrate surface...article 2012
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Naylor, G.A. (author), Scannell, R. (author), Beurskens, M. (author), Walsh, M.J. (author), Pastor, I. (author), Donné, A.J.H. (author), Snijders, B. (author), Biel, W. (author), Meszaros, B. (author), Giudicotti, L. (author), Pasqualotto, R. (author), Marot, L. (author)The central electron temperature and density of the ITER plasma may be determined by Thomson scattering. A LIDAR topology is proposed in order to minimize the port access required of the ITER vacuum vessel. By using a LIDAR technique, a profile of the electron temperature and density can be determined with a resolution of about 7 cm in the...article 2012
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Sibillano, T. (author), Ancona, A. (author), Rizzi, D. (author), Mezzapesa, F. (author), Konuk, A.R. (author), Aarts, R.G.K.M. (author), Huis in 't Veld, A.J. (author), Lugara, P.M. (author)In-process monitoring and feedback control are fundamental actions for stable and good quality laser welding process. In particular, penetration depth is one of the most critical features to be monitored. In this research, overlap welding of stainless steel is investigated to stably reproduce a fixed penetration depth using both CO2 and Nd:YAG...conference paper 2012
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Pellis, L. (author), van Erk, M.J. (author), van Ommen, B. (author), Bakker, G.C.M. (author), Hendriks, H.F.J. (author), Cnubben, N.H.P. (author), Kleemann, R. (author), van Someren, E.P. (author), Bobeldijk, I. (author), Rubingh, C.M. (author), Wopereis, S. (author)We introduce the metabolomics and proteomics based Postprandial Challenge Test (PCT) to quantify the postprandial response of multiple metabolic processes in humans in a standardized manner. The PCT comprised consumption of a standardized 500 ml dairy shake containing respectively 59, 30 and 12 energy percent lipids, carbohydrates and protein....article 2012
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van de Pas, N.C.A. (author), Woutersen, R.A. (author), van Ommen, B. (author), Rietjens, I.M.C.M. (author), de Graaf, A.A. (author)Increased plasma cholesterol concentration is associated with increased risk of cardiovascular disease. This study describes the development, validation, and analysis of a physiologically based kinetic (PBK) model for the prediction of plasma cholesterol concentrations in humans. This model was directly adapted from a PBK model for mice by...article 2012
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van Heesch, E.J.M. (author), Yan, K. (author), Pemen, A.J.M. (author), Winands, G.J.J. (author), Beckers, F.J.C.M. (author), Hoeben, W.F.L.M. (author)Smart electric power for process intensification is a challenging research field that integrates power engineering, chemistry and green technology. Pulsed power technology is offering elegant solutions. This work focuses on backgrounds of matching the power source to the process. Important items are reactor impedance, chemical reactions, plasma...article 2012
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de Jong, A.J. (author), van der Donck, J.C.J. (author), Huijser, T. (author), Kievit, O. (author), Koops, R. (author), Koster, N.B. (author), Molkenboer, F.T. (author), Theulings, A.M.M.G. (author)With the introduction of 450 mm wafers, which are considerably larger than the currently largest wafers of 300mm, handling with side grippers is no longer possible and backside grippers are required. Backside gripping increases the possible buildup of particles on the backside of the wafers with possible cross-contamination to the front-side....conference paper 2012
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Koster, N.B. (author), van der Donck, J.C.J. (author), Stortelder, J.K. (author), de Jong, A.J. (author), Molkenboer, F.T. (author)The introduction of EUV Lithography for the next node has two major obstacles at the moment; the first is source power and reliability and the second is defect free reticles and damage free cleaning of reticles. We present our results on our investigation for damage free cleaning of EUV reticles with remote plasma cleaning for molecular (carbon)...conference paper 2012
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Closed loop control of laser welding using an optical spectroscopic sensor for Nd:YAG and CO2 lasersKonuk, A.R. (author), Aarts, R.G.K.M. (author), Huis in 't Veld, A.J. (author), Sibillano, T. (author), Rizzi, D. (author), Ancona, A. (author)Recent developments in laser joining show the applicability of spectral analysis of the plasma plume emission to monitor and control the quality of weld. The analysis of the complete spectra makes it possible to measure specific emission lines which reveal information about the welding process. The subsequent estimation of the electron...conference paper 2011
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Jantos, R. (author), Schuhmacher, M. (author), Veldstra, J.L. (author), Bosker, W.M. (author), Klöpping-Ketelaars, I. (author), Touliou, K. (author), Sardi, G.M. (author), Brookhuis, K.A. (author), Ramaekers, J.G. (author), Mattern, R. (author), Skopp, G. (author)For forensic toxicological investigations only whole blood, but no serum is often available. Pharmacokinetic data are helpful for interpreting the results, but most of these studies indicate serum or plasma concentrations. In order to obtain reliable conversion factors which also take intersubject variability into account, the blood/serum ratios...article 2011
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van de Pas, N.C.A. (author), Woutersen, R.A. (author), van Ommen, B. (author), Rietjens, I.M.C.M. (author), de Graaf, A.A. (author)The LDL cholesterol (LDL-C) and HDL cholesterol (HDL-C) concentrations are determined by the activity of a complex network of reactions in several organs. Physiologically-based kinetic (PBK) computational models can be used to describe these different reactions in an integrated, quantitative manner. A PBK model to predict plasma cholesterol...article 2011