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van Lint, C.L. (author), Wang, W. (author), van Dijk, S. (author), Brinkman, W.P. (author), Rövekamp, T.J.M. (author), Neerincx, M.A. (author), Rabelink, T.J. (author), van der Boog, P.J.M. (author)Background: The high frequency of outpatient visits after kidney transplantation is burdensome to both the recovering patient and health care capacity. Self-monitoring kidney function offers a promising strategy to reduce the number of these outpatient visits. Objective: The objective of this study was to investigate whether it is safe to rely...article 2017
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van Koppen, E.J. (author), Schweizer, J.J. (author), Csizmadia, C.G.D.S. (author), Krom, Y. (author), Hylkema, H.B. (author), van Geel, A.M. (author), Koopman, H.M. (author), Verloove-Vanhorick, S.P. (author), Mearin, M.L. (author)OBJECTIVE. Mass screening for celiac disease is controversial. The objective of this study was to determine whether detection of childhood celiac disease by mass screening improves long-term health status and health-related quality of life. METHODS.We conducted a prospective 10-year follow-up study of 32 children who were aged 2 to 4 years, had...article 2009
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Buijs, P.C. (author), Lambeek, L.C. (author), Koppenrade, V. (author), Hooftman, W.E. (author), Anema, J.R. (author), TNO Kwaliteit van Leven (author)Introduction: Workers with chronic low back pain (LBP) mean a heavy human and social-economic burden. Their medical histories often include different treatments without attention to work-relatedness or communication with occupational health providers, leaving them passive and medicalized in (outpatient) health care. So we developed and...article 2009
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Kocken, P.L. (author), Zwanenburg, E.J.-v. (author), de Hoop, T. (author), TNO Kwaliteit van Leven (author)Objective: : The effectiveness of use of migrant health educators in the general practitioners' care for female migrants with psychosomatic problems was evaluated to contribute to the improvement of the care for these patients. Methods: : A randomised controlled trial (RCT) design was used. A total of 104 patients (75%) agreed to take part in...article 2008
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van Uffelen, J.G.Z. (author), Chinapaw, M.J.M. (author), van Mechelen, W. (author), Hopman-Rock, M. (author), TNO Kwaliteit van Leven (author)Objective: To examine the effects of aerobic exercise or vitamin B supplementation on cognitive function in older adults with mild cognitive impairment (MCI). Design: Randomised placebo-controlled trial. Setting: General community. Participants: Community-dwelling adults aged 70-80 with MCI. Interventions : The 152 participants were randomly...article 2008
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Balk, A.H. (author), Davidse, W. (author), van Dommelen, P. (author), Klaassen, E. (author), Caliskan, K. (author), van der Burgh, P. (author), Leenders, C.M. (author), TNO Kwaliteit van Leven (author), KvL (author)Background: New strategies are required to optimize care in increasing numbers of chronic heart failure patients. The aim of this randomised trial was to evaluate a remote guidance system. Methods: Intervention group patients received a home TV-channel providing educational materials. Tele-guidance was performed by a Medical Service Centre....article 2008
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TNO Kwaliteit van Leven (author), van Dellen, Q.M. (author), van Aalderen, W.M.C. (author), Bindels, P.J.E. (author), Öry, F.G. (author), Bruil, J. (author), Stronks, K. (author), Wennink, J.M.B. (author), Wolf, B.H.M. (author), Mahdi, U. (author), Nagelkerke, A.F. (author), van der Veer, E.M.A. (author), Westra, M. (author)Background. Doctors and patients hold varying beliefs concerning illness and treatment. Patients' and families' explanatory models (EMs) vary according to personality and sociocultural factors. In a multi-ethnic society, it is becoming increasingly significant that doctors understand the different beliefs of their patients in order to improve...article 2008
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TNO Kwaliteit van Leven (author), Chanteranne, B. (author), Branca, F. (author), Kardinaal, A. (author), Wahala, K. (author), Braesco, V. (author), Ladroite, P. (author), Brouns, F. (author), Coxam, V. (author)The estrogenic effects of soy isoflavones (IF) on symptoms of menopause are of particular interest. The aim of the present study was to improve compliance of IF in two IF-enriched foods providing the same IF circulating levels in postmenopausal women. Forty-two healthy postmenopausal women (mean age: 53.28 years) were recruited for a randomized,...article 2008
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van Uffelen, J.G.Z. (author), Chin A Paw, M.J.M. (author), Hopman-Rock, M. (author), van Mechelen, W. (author), TNO Kwaliteit van Leven (author)Objectives: To examine the effect of walking and vitamin B supplementation on quality-of-life (QoL) in community-dwelling adults with mild cognitive impairment. Methods: One year, double-blind, placebo-controlled trial. Participants were randomized to: (1) twice-weekly, group-based, moderate-intensity walking program (n = 77) or a light...article 2007
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Kennedy, S. (author), Jin, X. (author), Yu, H. (author), Zhong, S. (author), Magill, P. (author), van Vliet, T. (author), Kistemaker, C. (author), Voors, C. (author), Pasman, W. (author), TNO Kwaliteit van Leven (author)A proof-of-concept study to assess the safety and efficacy of a traditional Chinese medicine formula as treatment for primary dysmenorrhea showed no statistically significant benefit over placebo. However, some efficacy parameters suggested possible superiority of the active treatment and so a larger study needs to be performed to determine...article 2006
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van Doorn, M.B.A. (author), Espirito Santo, S.M. (author), Meijer, P. (author), Kamerling, I.M. (author), Schoemaker, R.C. (author), Dirsch, V. (author), Vollmar, A. (author), Haffner, T. (author), Gebhardt, R. (author), Cohen, A.F. (author), Princen, H.M. (author), Burggraaf, J. (author), TNO Kwaliteit van Leven (author)Background: Epidemiologic studies suggest that garlic may have beneficial effects on risk factors associated with cardiovascular disease (CVD). However, these findings are not unambiguously supported by randomized placebo-controlled clinical trials. Objective: We sought to investigate the effects of a chemically well-characterized garlic...article 2006
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van Dellen, Q.M. (author), Stronks, K. (author), Bindels, P.J.E. (author), Öry, F.G. (author), van Aalderen, W.M.C. (author), TNO Kwaliteit van Leven (author)Poor adherence to inhaled corticosteroids (ICSs) may contribute to the recent rise in asthma morbidity. In general, appropriate adherence to ICSs is a complex process that is influenced by various determinants. The purpose of this study was to identify factors that were associated with adherence to ICSs in children with asthma and their parents...article 2006
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Finglas, P.M. (author), de Meer, K. (author), Molloy, A. (author), Verhoef, P. (author), Pietrzik, K. (author), Powers, H.J. (author), van der Straeten, D. (author), Jägerstad, M. (author), Varela-Moreiras, G. (author), van Vliet, T. (author), Havenaar, R. (author), Buttriss, J. (author), Wright, A.J.A. (author), TNO Kwaliteit van Leven (author)In the past decade, the understanding of folate bioavailability, metabolism and related health issues has increased, but several problems remain, including the difficulty of delivering the available knowledge to the populations at risk. Owing to the low compliance of taking folic acid supplements, for example, among women of child-bearing age...article 2006
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Visser, O. (author), van Peppen, A.M. (author), Öry, F.G. (author), van Leeuwen, F.E. (author), TNO Preventie en Gezondheid (author)To determine breast cancer screening results according to country of birth data were used from the breast cancer screening organization of the Comprehensive Cancer Centre Amsterdam, the Netherlands. Overall (age-adjusted) attendance of the breast cancer screening was 76% for women aged 50-69. Attendance was significantly lower for women born in...article 2005
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Crone, M.R. (author), Spronsen, F.J. (author), Oudshoorn, K. (author), Bekhof, J. (author), van Rijn, G. (author), Verkerk, P.H. (author), TNO Preventie en Gezondheid (author)Background. The objective of this study was to determine the importance of parental factors possibly related to dietary control in early and continuously treated patients with phenylketonuria (PKU). Methods. A questionnaire was disseminated among parents of 238 patients with PKU born after the nationwide introduction of newborn screening for PKU...article 2005
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Boshuizen, H.C. (author), Stemmerik, L. (author), Westhoff, M.H. (author), Hopman-Rock, M. (author), TNO Kwaliteit van Leven (author)Elderly participants experiencing difficulty in chair rising and with a maximum knee-extensor torque below 87.5 N · m were randomized to different versions of a strength-training program for the knee-extensors: to a high-guidance group (HG; two group sessions supervised by a physical therapist and one unsupervised home session per week, n = 17),...article 2005
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van der Greef, J. (author), McBurney, R.N. (author), TNO Kwaliteit van Leven (author)The pharmaceutical industry is currently beleaguered by close scrutiny from the financial community, regulators and the general public. Productivity, in terms of new drug approvals, has generally been falling for almost a decade and the safety of a number of highly successful drugs has recently been brought into question. Here, we discuss...article 2005
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TNO Preventie en Gezondheid (author), Forsén, L. (author), Sandvig, S. (author), Schuller, A. (author), Søgaard, A.J. (author)Objectives: To investigate compliance with hip protector use. Design: Observational prospective study. Setting: 19 nursing homes (1040 beds). Subjects: All residents during an 18 month period were included in this study. Intervention: Hip protectors were introduced as a regular part of health care service for all residents. Residents at high...article 2004
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Broekmans, W.M.R. (author), Klöpping-Ketelaars, I.A.A. (author), Weststrate, J.A. (author), Tijburg, L.B.M. (author), van Poppel, G. (author), Vink, A.A. (author), Berendschot, T.T.J.M. (author), Bots, M.L. (author), Castenmiller, W.A.M. (author), Kardinaal, A.F.M. (author)Excessive consumption of energy and fat increases the risk for obesity. Snacks containing sucrose polyesters (SPE) as a dietary fat replacer are on the market in the United States. SPE products have been shown to lower concentrations of serum carotenoids in short-term studies. Experimental studies on the longer-term effects on health of...article 2003
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Forsén, L. (author), Arstad, C. (author), Sandvig, S. (author), Schuller, A. (author), Røed, U. (author), Søgaard, A.J. (author), TNO Preventie en Gezondheid (author)Aims: This study was undertaken to estimate the effect of hip protectors on the incidence of hip fracture when introduced into nursing homes as a regular part of the healthcare for all residents. Methods: A pre-test/test design was used. The pre-intervention period lasted 18 months from May 1996. The intervention period lasted 18 months from May...article 2003
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