The possibilities of the use of N-of-1 and do-ityourself trials in nutritional research

Background. N-of-1 designs gain popularity in nutritional research because of the improving technological possibilities, practical applicability and promise of increased accuracy and sensitivity, especially in the field of personalized nutrition. This move asks for a search of applicable statistical methods. Objective. To demonstrate the...

Measuring health promotion: translating science into policy

Commonly, it is the end of life when our health is deteriorating, that many will make drastic lifestyle changes to improve their quality of life. However, it is increasingly recognized that bringing good health-promoting behaviors into practice as early in life as possible has the most significant impact across the maximal healthspan. The WHO...

Inflammation and nutritional science for programs/policies and interpretation of research evidence (INSPIRE)

An increasing recognition has emerged of the complexities of the global health agenda-specifically, the collision of infections and noncommunicable diseases and the dual burden of over- and undernutrition. Of particular practical concern are both 1) the need for a better understanding of the bidirectional relations between nutritional status and...

EURRECA Development of tools to improve the alignment of micronutrient recommendations

Approaches through which reference values for micronutrients are derived, as well as the reference values themselves, vary considerably across countries. Harmonisation is needed to improve nutrition policy and public health strategies. The EURRECA (EURopean micronutrient RECommendations Aligned, http://www.eurreca.org) Network of Excellence is...

Effective elements of school health promotion across behavioral domains: A systematic review of reviews

Background. Most school health education programs focus on a single behavioral domain. Integrative programs that address multiple behaviors may be more efficient, but only if the elements of change are similar for these behaviors. The objective of this study was to examine which effective elements of school health education are similar across...

Krachtvoer: Effect evaluation of a Dutch healthful diet promotion curriculum for lower vocational schools

Objective: The aim of this study was to assess the behavioural effects of a school-based healthful diet promotion intervention implemented in lower vocational schools. Design: A cluster-randomised pre-test-post-test experimental design was used, and data were collected by means of written questionnaires. Setting: Students of 18 Dutch lower...

The challenges for molecular nutrition research 2: Quantification of the nutritional phenotype

In quantifying the beneficial effect of dietary interventions in healthy subjects, nutrition research meets a number of new challenges. Inter individual variation in biomarker values often is larger than the effect related to the intervention. Healthy subjects have a remarkable capacity to maintain homeostasis, both through direct metabolic...

The EPIC nutrient database project (ENDB): A first attempt to standardize nutrient databases across the 10 European countries participating in the EPIC study

Objective: This paper describes the ad hoc methodological concepts and procedures developed to improve the comparability of Nutrient databases (NDBs) across the 10 European countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). This was required because there is currently no European reference NDB...

Personalized nutrition from a health perspective: Luxury or necessity?

Nutrigenomics: The impact of biomics technology on nutrition research

The interaction between the human body and nutrition is an extremely complex process involving multi-organ physiology with molecular mechanisms on all levels of regulation (genes, gene expression, proteins, metabolites). Only with the recent technology push have nutritional scientists been able to address this complexity. Both the challenges and...

Nutrigenomics: Exploiting systems biology in the nutrition and health arenas

Selective oxidation of polysaccharides, a tool for carbohydrate-based alternatives for Carbopol®

Approach of the US food and nutrition board to daily nutrient requirements: A useful basis for the European discussion on risk assessment of nutrients

Objective: To discuss the approach of the US Food and Nutrition Board (FNB) to daily nutrient requirements and its relevance for Europe. Setting: A workshop for experts from academia and regulatory bodies, together with members from the FNB Dietary Reference Intakes Subcommittee on Upper Reference Levels of Intake, and from the B-vitamins Expert...

Improvements in the determination of vitamins in foods: Method intercomparison studies and preparation of certified reference materials (CRMs)

Accurate methods for the determination of vitamins in food are required for nutritional labelling, and for the production of food composition data for nutritional research on relationships between diet and health. The Standards, Measurement and Testing Programme of the European Commission is supporting a collaborative project involving 48...