Anthropometry, physical activity, and endometrial cancer risk: Results from the Netherlands Cohort Study

Although obesity is an established risk factor for endometrial cancer, evidence linking risk to height, weight change since age 20, and physical activity is limited. In this case-cohort study, 62 573 women from The Netherlands Cohort Study on Diet and Cancer were followed up from 1986 to 1995, and 226 endometrial cancer case patients were...

Beat-to-beat noninvasive stroke volume from arterial pressure and Doppler ultrasound

The proper understanding of the cardiovascular mechanisms involved in complaints of short-lasting dizziness and the evaluation of unexplained recurrent syncope requires continuous monitoring of cardiac stroke volume (SV) in addition to blood pressure and heart rate. The primary aim of the present study was to evaluate a pulse wave analysis...

The bispyridinium-dioxime HLö-7. A potent reactivator for acetylcholinesterase inhibited by the stereoisomers of tabun and soman

Purification of (+)-tabun was accomplished by treatment with electric eel acetylcholinesterase (AChE) in order to bind contaminating (-)-tabun, the more potent enantiomer with respect of AChE inhibition. Electric eel AChE inhibited with (-)-tabun and with purified (+)-tabun show similar properties in reactivation reactions with oximes (pH 7.5,...

The actual insulation of multilayer clothing

The effect of geometric factors on insulation was calculated mathematically for standing humans. It was found that internal radiative heat transfer in an ensemble was significant for insulation, that intrinsic clothing insulation is a useful concept only for indoor climates, and that shape plays a minor role. The literature agrees closely on...

An empirical study of subjective road categorization

Driver behaviour will partially be a function of the cognitive schemata by which drivers represent features, functions and operations of traffic system components. This paper uses the Repertory Grid Technique to address the questions: (1) How do drivers internally represent different categories of road? (2) How are those representations mapped...

The limits of path error-neglecting in straight lane driving

It is argued that driving cannot simply be considered as a permanent, closed-loop task. Time-to-line-crossing (TLC) is used as a measure to quantify the potential role of visual open-loop and path-error-neglecting strategies. Basically, TLC represents the time available for a driver to neglect path errors until the moment at which any part of...

Effects of an oil spill in outdoor model tidal flat ecosystems

Kinetic profile in blood and brain of the cholinesterase reactivating oxime HI-6 after intravenous administration to the rat

The kinetic profile of the oxime HI-6, a potent cholinesterase reactivator, after iv administration of 0.1325 mmol/kg (50 mg/kg) to rats is described. The blood concentrations measured over a period of 300 min can be described by a two-compartment open model. Excretion occurred only by the kidney. Approximately 60% was excreted in unmetabolized...

Measurement of the electrotonic length constant in cultured muscle fibres

The measurement of passive electrical membrane properties in cultured muscle cells is complicated by the fact that the electrotonic length in these cells often exceeds their actual length, leading to serious deviations from the simple infinite cable behaviour. By using very short current pulses for these measurements and integrating the...