Searched for: subject%3A%22lipid%255C%2Bblood%255C%2Blevel%22
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Beekman, M. (author), Heijmans, B.T. (author), Martin, N.G. (author), Whitfield, J.B. (author), Pedersen, N.L. (author), de Faire, U. (author), Snieder, H. (author), Lakenberg, N. (author), Suchiman, H.E.D. (author), de Knijff, P. (author), Frants, R.R. (author), van Ommen, G.J.B. (author), Kluft, C. (author), Vogler, G.P. (author), Boomsma, D.I. (author), Slagboom, P.E. (author)
The genetic basis of cardiovascular disease (CVD) with its complex etiology is still largely elusive. Plasma levels of lipids and apolipoproteins are among the major quantitative risk factors for CVD and are well-established intermediate traits that may be more accessible to genetic dissection than clinical CVD end points. Chromosome 19 harbors...
article 2003
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Broekmans, W.M.R. (author), Klöpping-Ketelaars, I.A.A. (author), Weststrate, J.A. (author), Tijburg, L.B.M. (author), van Poppel, G. (author), Vink, A.A. (author), Berendschot, T.T.J.M. (author), Bots, M.L. (author), Castenmiller, W.A.M. (author), Kardinaal, A.F.M. (author)
Excessive consumption of energy and fat increases the risk for obesity. Snacks containing sucrose polyesters (SPE) as a dietary fat replacer are on the market in the United States. SPE products have been shown to lower concentrations of serum carotenoids in short-term studies. Experimental studies on the longer-term effects on health of...
article 2003
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van de Vijver, L.P.L. (author), Kardinaal, A.F.M. (author), Couet, C. (author), Aro, A. (author), Kafatos, A. (author), Steingrimsdottir, L. (author), Amorim Cruz, J.A. (author), Moreiras, O. (author), Becker, W. (author), van Amelsvoort, J.M.M. (author), Vidal-Jessel, S. (author), Salminen, I. (author), Moschandreas, J. (author), Sigfússon, N. (author), Martins, I. (author), Carbajal, A. (author), Ytterfors, A. (author), van Poppel, G. (author)
Background: High intakes of trans fatty acids (TFA) have been found to exert an undersirable effect on serum lipid profiles, and thus may increase the risk for cardiovascular disease. Objective: Investigation of the association between TFA intake and serum lipids. Design: Cross-sectional study in eight European countries (Finland, France, Greece...
article 2000
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van Dokkum, W. (author), Wezendonk, B. (author), Srikumar, T.S. (author), van den Heuvel, E.G.H.M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective: To study the effect of the intake of 15 g nondigestible oligosaccharides per day on various parameters of large-bowel function, as well as on blood lipid concentrations and glucose absorption in man. Design: Latin square, randomized, double-blind, diet-controlled. Setting: Metabolic research unit. Subjects: Twelve apparently healthy...
article 1999
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Weststrate, J.A. (author), van het Hof, K.H. (author), van den Berg, H. (author), te Velthuis-te-Wierik, E.J.M. (author), de Graaf, C. (author), Zimmermanns, N.J.H. (author), Westerterp, K.R. (author), Westerterp-Plantenga, M.S. (author), van de Verboeket-Venne, W.P.H.G. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objectives: To compare the effects of free access to reduced fat products or their full fat equivalents on fat and energy intake, body weight, plasma lipids and fat-soluble antioxidants concentrations and haemostasis variables. Design: A multicentre open randomised controlled trial in which intervention and control groups were followed in...
article 1998
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Schaafsma, G. (author), Meuling, W.J.A. (author), van Dokkum, W. (author), Bouley, C. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Objective: To investigate in adult male volunteers the effect of a new fermented milk product, fermented by Lactobacillus acidophilus and with fructo-oligosaccharides added, on blood lipids. Design: Randomized placebo-controlled double-blind two-way cross over trial with two treatment periods of three weeks, separated by a wash-out period of one...
article 1998
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Boer, J.M.A. (author), Ehnholm, C. (author), Menzel, H.J. (author), Havekes, L.M. (author), Rosseneu, M. (author), O'Reilly, D.S.J. (author), Tiret, L. (author), Gaubius Instituut TNO (author)
To elucidate how the apolipoprotein (apo)E polymorphism and modifiable factors interact in explaining plasma lipid and apolipoprotein levels, we studied 1448 young adults (18 to 26 years old), participating in the European Atherosclerosis Research Study (EARS). Venous blood was collected after an overnight fast. Modifiable factors, eg, body mass...
article 1997
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van de Vijver, L.P.L. (author), van Duyvenvoorde, W. (author), Buytenhek, R. (author), van der Laarse, A. (author), Kardinaal, A.F.M. (author), van den Berg, H. (author), Princen, H.M.G. (author)
article 1997
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Virtanen, S.M. (author), van 't Veer, P. (author), Kok, F. (author), Kardinaal, A.F.M. (author), Aro, A. (author)
The adipose tissue carotenoid (alpha-carotene, beta-carotene, and lycopene) and retinol levels and their predictors were determined in 686 male and 339 female middle-aged and elderly subjects from eight European countries and Israel during the years 1991 to 1992. Adipose tissue carotenoid levels in men were 50-76% of those in women, whereas the...
article 1996
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Hasler-Rapacz, J. (author), Kempen, H.J. (author), Princen, H.M.G. (author), Kudchodkar, B.J. (author), Lacko, A. (author), Rapacz, J. (author), Gaubius Instituut TNO (author)
Familial hypercholesterolemia (FHC) in swine, which resembles human familial combined hyperlipidemia, is a complex lipid and lipoprotein disorder associated with the development of severe coronary lesions similar to those occurring in advanced human coronary disease. The disorder is characterized by elevated plasma total cholesterol (TC),...
article 1996
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te Velthuis- Wierik, E.J.M. (author), van den Berg, H. (author), Weststrate, J.A. (author), van het Hof, K.H. (author), de Graaf, C. (author), TNO Voeding (author)
Objective: Dietary fat intake is higher than recommended in most western countries and is associated with the prevalence of cardiovascular diseases, obesity and cancer. The growing public concern about the adverse effects of a high fat intake has led to an increased availability of 'reduced-fat' products. Consumption of reduced-fat products...
article 1996
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Hau, M.-F. (author), Smelt, A.H.M. (author), Bindels, A.J.G.H. (author), Sijbrands, E.J.G. (author), van der Laarse, A. (author), Onkenhout, W. (author), van Duyvenvoorde, W. (author), Princen, H.M.G. (author), Gaubius Instituut TNO (author)
In hypertriglyceridemic (HTG) patients the addition of fish oil to the diet causes a marked reduction in the concentration of triglyceride-rich lipoproteins in the serum. To investigate the effects of fish oil on the oxidation resistance of VLDL and LDL in HTG patients, nine male patients received 1 g/d fish oil (containing 55.7% n-3...
article 1996
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Gaubius Instituut TNO (author), de Knijff, P. (author), Rosseneu, M. (author), Beisiegel, U. (author), de Keersgieter, W. (author), Frants, R.R. (author), Havekes, L.M. (author)
Recently, we determined the apolipoprotein E (apoE) phenotype distribution in 2,000 randomly selected 35-year-old male individuals by slab gel isoelectric focusing of delipidated plasma samples, followed by immunoblotting using anti-apoE antiserum. These blots have been successfully re-used for immunovisualization of apoA-IV isoelectric focusing...
article 1988
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Pikaar, N.A. (author), Wedel, M. (author), van der Beek, E.J. (author), van Dokkum, W. (author), Kempen, H.J.M. (author), Kluft, C. (author), Ockhuizen, T. (author), Hermus, R.J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
To investigate the effect of moderate alcohol consumption on blood constituents related to cardiovascular disease, 12 male volunteers consumed (instead of their usual alcoholic drinks) four different standardized amounts of red wine in addition to their habitual diet. Each dose was given to the subjects during a period of 5 weeks in a randomized...
article 1987
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van der Beek, E.J. (author), Wedel, M. (author), van de Zedde, A. (author), Bovens, M. (author), Leep, B.J. (author), Hermus, R.J.J. (author), Schouten, J.A. (author), van der Veen, E.A. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)
Twenty seven male patients, with Type-I diabetes mellitus were studied, all from the Outpatient Clinic of the Department of Internal Medicine, the Free University Hospital, Amsterdam. In comparison with healthy subjects and as regards age, total cholesterol and LDL-cholesterol levels were within normal limits, although HDL-cholesterol and...
article 1984
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