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van Bilsen, J.H.M. (author), van den Brink, W. (author), van den Hoek, A.M. (author), Dulos, R. (author), Caspers, M.P.M. (author), Kleeman, R. (author), Wopereis, S. (author), Verschuren, L. (author)Metabolic disorders, such as obesity and type 2 diabetes have a large impact on global health, especially in industrialized countries. Tissue-specific chronic low-grade inflammation is a key contributor to complications in metabolic disorders. To support therapeutic approaches to these complications, it is crucial to gain a deeper understanding...article 2021
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Regeer, H. (author), Nieuwenhuijse, E.A. (author), Vos, R.C. (author), Kiefte-de Jong, J.C. (author), van Empelen, P. (author), de Koning, E.J.P. (author), Bilo, H.J.G. (author), Huisman, S.D. (author)Aims: To investigate changes in physical activity (PA) and psychological factors during societal lockdown in people with type 2 diabetes. Methods: A cross-sectional study among Dutch adults with type 2 diabetes. Data were collected using online questionnaires. A multivariate multinomial logistic regression was performed with change in PA during...article 2021
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Wagner, A. (author), Cohen, N. (author), Kelder, T. (author), Amit, U. (author), Liebman, E. (author), Steinberg, D.M. (author), Radonjic, M. (author), Ruppin, E. (author)High-throughput omics have proven invaluable in studying human disease, and yet day-to-day clinical practice still relies on physiological, non-omic markers. The metabolic syndrome, for example, is diagnosed and monitored by blood and urine indices such as blood cholesterol levels. Nevertheless, the association between the molecular and the...article 2015
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TNO Kwaliteit van Leven (author), Boelsma, E. (author), Kloek, J. (author)Background. Milk derived peptides have been identified as potential antihypertensive agents. The primary objective was to investigate the effectiveness of IPP-rich milk protein hydrolysates (MPH) on reducing blood pressure (BP) as well as to investigate safety parameters and tolerability. The secondary objective was to confirm or falsify ACE...article 2010
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Gubbels, J.S. (author), Kremers, S.P.J. (author), Stafleu, A. (author), Dagnelie, P.C. (author), de Vries, S.I. (author), de Vries, N.K. (author), Thijs, C. (author), TNO Kwaliteit van Leven (author)Objective: To examine clustering of energy balance-related behaviors (EBRBs) in young children. This is crucial because lifestyle habits are formed at an early age and track in later life. This study is the first to examine EBRB clustering in children as young as 2 years. Study design: Cross-sectional data originated from the Child, Parent and...article 2009
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TNO Kwaliteit van Leven (author), van Wier, M.F. (author), Arins, G.A.M. (author), Dekkers, J.C. (author), Hendriksen, I.J.M. (author), Smid, T. (author), van Mechelen, W. (author)Background. The work setting provides an opportunity to introduce overweight (i.e., Body Mass Index 25 kg/m2) adults to a weight management programme, but new approaches are needed in this setting. The main purpose of this study was to investigate the effectiveness of lifestyle counselling by phone or e-mail on body weight, in an overweight...article 2009