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Berg, S. (author), Leng, M.J. (author), Kendrick, C.P. (author), Cremer, H. (author), Wagner, B. (author)Organic carbon occluded in diatom silica is assumed to be protected from degradation in the sediment. δ13C from diatom carbon (δ13C(diatom)) therefore potentially provides a signal of conditions during diatom growth. However, there have been few studies based on δ13C(diatom). Numerous variables can influence δ13C of organic matter in the marine...article 2013
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Cremer, H. (author), Bunnik, F.P.M. (author), Donders, T.H. (author), Hoek, W.Z. (author), Koolen-Eekhout, M. (author), Koolmees, H.H. (author), Lavooi, E. (author), TNO Bouw en Ondergrond (author)A 400-year sediment record from an 18 m deep scour hole lake (Haarsteegse Wiel) near the Meuse River in the Netherlands was investigated for past changes in water quality, flooding frequency and landscape change using geophysical, geochemical and micropaleontological information. The results are highly significant for determining long-term...article 2010
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Frewer, L.J. (author), Davies, O.H. (author), van Rijswijk, W. (author), Lucas Luijckx, N.B. (author), Ward, S. (author), TNO Kwaliteit van Leven (author)The modified European Food Law (General Food Law) has been emphasizing on the need to increase consumer confidence through implementation of regulatory measures focused on increased traceability in food chain. The implementation of effective traceability systems can provide the basis of communication between actors in the production chain, and...article 2008
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Coulier, L. (author), Bradley, E.L. (author), Bas, R.C. (author), Verhoeckx, K.C.M. (author), Driffield, M. (author), Harmer, N. (author), Castle, L. (author), TNO Kwaliteit van Leven (author)Bisphenol A diglycidyl ether (BADGE) is an epoxide that is used as a starting substance in the manufacture of can coatings for food-contact applications. Following migration from the can coating into food, BADGE levels decay and new reaction products are formed by reaction with food ingredients. The significant decay of BADGE was demonstrated by...article 2010
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Lombardi, P. (author), Mulder, M. (author), de Wit, E. (author), van Berkel, T.J.C. (author), Frants, R.R. (author), Havekes, L.M. (author), Instituut voor verouderings- en vaatziekten onderzoek TNO (author)In previous studies we have shown that in HepG2 cells, as compared with fibroblasts, the low-density lipoprotein (LDL) receptor is only weakly down-regulated upon incubation of the cells with LDL. To explain this difference in down-regulation of the LDL-receptor activity, we studied simultaneously the intracellular processing of 125I-labelled...article 1993
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Heiri, O. (author), Cremer, H. (author), Engels, S. (author), Hoek, W.Z. (author), Peeters, W. (author), Lotter, A.F. (author), TNO Bouw en Ondergrond (author)Lateglacial environments at Hijkermeer, northwest Netherlands, were reconstructed by means of chironomid, diatom and pollen analyses. Diatom assemblages indicate that Hijkermeer was a shallow, oligo- to mesotrophic lake during this period. Pollen assemblages reflect the typical northwest European Lateglacial vegetation development and provide an...article 2007
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Fox, T.E. (author), van den Heuvel, E.G.H.M. (author), Atherton, C.A. (author), Dainty, J.R. (author), Lewis, D.J. (author), Langford, N.J. (author), Crews, H.M. (author), Luten, J.B. (author), Lorentzen, M. (author), Sieling, F.W. (author), van Aken-Schneyder, P. (author), Hoek, M. (author), Kotterman, M.J.J. (author), van Dael, P. (author), Firweather-Tail, S.J. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)Objective: To measure the bioavailability of selenium from cooked and raw fish in humans by estimating and comparing apparent absorption and retention of selenium in biosynthetically labelled fish with labelled selenate and biosynthetically labelled selenium in brewers yeast. Design: The intervention study was a parallel, randomised, reference...article 2004
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Walraven, N. (author), van Os, B.J.H. (author), Klaver, G.Th. (author), Baker, J.H. (author), Vriend, S.P. (author), Rijks Geologische Dienst (author)Graft-De Rijp is a former village of whalers, situated twenty-five kilometres north of Amsterdam, the Netherlands. Since the foundation of De Rijp in 1612 a mixture of sludge, manure and town refuse (containing Pb-based household artefacts and Pb-based building materials) was used to raise and fertilise the land. Gasworks, coal storehouses,...article 1997
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Eggenkamp, H.G.M. (author), Louvat, P. (author), Agrinier, P. (author), Bonifacie, M. (author), Bekker, A. (author), Krupenik, V. (author), Griffioen, J. (author), Horita, J. (author), Brocks, J.J. (author), Bagheri, R. (author)We determined the chlorine and bromine isotope compositions of 83 halite samples from nine different geological periods between the Orosirian and the present in order to study the secular Cl and Br isotope variations in the ocean during the last 2 billion years. Relatively large Cl (-0.24 to +0.51%e vs. SMOC) and Br ( —0.24 to +1.08%e vs. SMOB)...article 2019
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Visser, A. (author), Broers, H.P. (author), Bierkens, M.F.P. (author), TNO Bouw en Ondergrond (author)The production of gases in groundwater under contaminated locations by geochemical and biological processes is not uncommon. Degassing of these gases from groundwater and repartitioning of noble gases between water and gas phase distorts groundwater dating by 3H/3He. We observed noble gas concentrations below atmospheric equilibrium in 20 out of...article 2007
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de Bie, A.T.H.J. (author), van Ommen, B. (author), Bär, A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)The absorption, disposition, metabolism, and excretion of 14C-labeled γ-cyclodextrin ([14C]γ-CD) was examined in four separate experiments with Wistar rats. In experiment 1, [14C]γ-CD (25 μCi, 600 mg/kg body wt) was administered intravenously to four male and four female conventional rats. In experiment 2, [14C]γ- CD (25 μCi, 1000 mg/kg body wt)...article 1998
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Brust, H. (author), Koeberg, M. (author), van der Heijden, A. (author), Wiarda, W. (author), Mügler, I. (author), Schrader, M. (author), Vivo-Truyols, G. (author), Schoenmakers, P. (author), van Asten, A. (author)Ammonium nitrate (AN) is frequently encountered in explosives in forensic casework. It is widely available as fertilizer and easy to implement in explosive devices, for example by mixing it with a fuel. Forensic profiling methods to determine whether material found on a crime scene and material retrieved from a suspect arise from the same source...article 2015
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Zhang, Y.C. (author), Slomp, C.P. (author), Broers, H.P. (author), Bostick, B. (author), Passier, H.F. (author), Böttcher, M.E. (author), Omoregie, E.O. (author), Lloyd, J.R. (author), Polya, D.A. (author), van Cappellen, P. (author)Denitrification driven by pyrite oxidation can play a major role in the removal of nitrate from groundwater systems. As yet, limited information is available on the interactions between the micro-organisms and aqueous and mineral phases in aquifers where pyrite oxidation is occurring. In this study, we examine the groundwater and sediment...article 2012
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Randerath, K. (author), Sriram, P. (author), Moorthy, B. (author), Aston, J.P. (author), Baan, R.A. (author), van den Berg, P.T.M. (author), Booth, E.D. (author), Watson, W.P. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)32P-postlabelling analysis for detecting DNA adducts formed by polycyclic aromatic compounds is one of the most widely used techniques for assessing genotoxicity associated with these compounds. In cases where the formation of adducts is extremely low, a crucial step in the analysis is an enrichment procedure for adducts prior to the...article 1998
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van den Berg, K.J. (author), Betel, I. (author), Radiobiologisch Instituut TNO (author)Chemicals/CAS: 2 amino 2 methylpropionic acid, 62-57-7; carbon, 7440-44-0; thymidine, 50-89-5; tritium, 10028-17-8; Aminoisobutyric Acids; Carbon Isotopes; Lectins; Thymidine, 50-89-5; Tritium, 10028-17-8article 1971
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van der Wateren, F.M. (author), Dunai, T.J. (author), van Balen, R.T. (author), Klas, W. (author), Verbers, A.L.L.M. (author), Passchier, S. (author), Herpers, U. (author), Nederlands Instituut voor Toegepaste Geowetenschappen TNO (author)Separate regions within the Transantarctic Mountains, the uplifted flank of the West Antarctic rift system, appear to have distinct Neogene histories of glaciation and valley downcutting. Incision of deep glacial outlet valleys occurred at different times throughout central and northern Victoria Land. This is corroborated by measurements of...article 1999
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Meijer, T. (author), Cleveringa, P. (author), Munsterman, D.K. (author), Verreussel, R.M.C.H. (author), TNO Bouw en Ondergrond (author)In this paper, the currently accepted correlation of the Early Pleistocene Ludhamian stage of England with the Tiglian-A sub-stage of the Netherlands is challenged. Recent investigations of Early Pleistocene marine North Sea deposits from a borehole near Noordwijk (the Netherlands) yielded evidence from molluscs, dinoflagellate cysts and...article 2006
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Mertens, J. (author), Brachert, L. (author), Desagher, D. (author), Thielens, M.L. (author), Khakharia, P.M. (author), Goetheer, E.L.V. (author), Schaber, K. (author)Recently, studies have appeared pointing out that aerosols can dominate the total amine emission from amine based PCCC pilot plant scale installations. For the design of countermeasure types (upstream or downstream of the PCCC installation), it is crucial to have an idea of the aerosol size distribution and numbers entering or leaving the...article 2014
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van de Schootbrugge, B. (author), Houben, A.J.P. (author), Ercan, F.E.Z. (author), Verreussel, R. (author), Kerstholt, S. (author), Janssen, N.M.M. (author), Nikitenko, B. (author), Suan, G. (author)The Toarcian Oceanic Anoxic Event (T-OAE, c. 182 Ma) represents a major perturbation of the carbon cycle marked by widespread black shale deposition. Consequently, the onset of the T-OAE has been linked to the combined effects of global warming, high productivity, basin restriction and salinity stratification. However, the processes that led to...article 2019
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Bleichrodt, J.F. (author), Verheij, W.S.D. (author), Medisch Biologisch Laboratorium TNO (author)Amber mutants of bacteriophage can be reverted by ionizing radiation to pseudo wild type particles, i.e. particles able to propagate in a suppressorless host. Since the DNA of phi X 174 is single stranded mutation cannot be due to errors in repair of radiation damage by the excision repair or by the recombination repair system of the host cell,...article 1973