Gut-on-a-Chip Research for Drug Development: Implications of Chip Design on Preclinical Oral Bioavailability or Intestinal Disease Studies

Individual and Group-Based Effects of in vitro Fiber Interven-tions on the Fecal Microbiota

2'-Fucosyllactose inhibits proliferation of Clostridioides difficile ATCC 43599 in the CDi-screen, an in vitro model simulating Clostridioides difficile infection

A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo

Applicability of generic PBK modelling in chemical hazard assessment: A case study with IndusChemFate

Advanced epithelial lung and gut barrier models demonstrate passage of microplastic particles

Microphysiological Systems to Recapitulate the Gut–Kidney Axis

The potential of multi-organ-on-chip models for assessment of drug disposition as alternative to animal testing

The progress of intestinal epithelial models from cell lines to gut-on-chip

Towards human ex vivo organ perfusion models to elucidate drug pharmacokinetics in health and disease

Setting the stage for next-generation risk assessment with non-animal approaches the EU-ToxRisk project experience

Characterization of Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mature Features and Potential for Modeling Metabolic Diseases

COST Action 'ImpARAS': What have we learnt to improve food allergy risk assessment. A summary of a 4 year networking consortium

Appetite ratings of foods are predictable with an in vitro advanced gastrointestinal model in combination with an in silico artificial neural network

Applying the adverse outcome pathway (AOP) for food sensitization to support in vitro testing strategies

The relevance of a digestibility evaluation in the allergenicity risk assessment of novel proteins. Opinion of a joint initiative of COST action ImpARAS and COST action INFOGEST

Interactions between acetylcholinesterase, toxic organophosphorus compounds and a short series of structurally related non-oxime reactivators: Analysis of reactivation and inhibition kinetics in vitro

Air-liquid interface In Vitro models for respiratory toxicology research: Consensus workshop and recommendations

Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility

Approaches to assess IgE mediated allergy risks (sensitization and cross-reactivity) from new or modified dietary proteins