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Keemink, A.Q.L. (author), Brug, T.J.H. (author), van Asseldonk, E.H.F. (author), Wu, A.R. (author), van der Kooij, H. (author)Active prosthetic and orthotic devices have the potential to increase quality of life for individuals with impaired mobility. However, more research into human-like control methods is needed to create seamless interaction between device and user. In forward simulations the reflex-based neuromuscular model (RNM) by Song and Geyer shows promising...article 2021
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Kloek, C.J.J. (author), Bossen, D. (author), de Vries, H.J. (author), de Bakker, D.H. (author), Veenhof, C. (author), Dekker, J. (author)E-Exercise is an effective 12-week blended intervention consisting of around five face-to-face physiotherapy sessions and a web-based application for patients with hip/knee osteoarthritis. In order to facilitate effective implementation of e-Exercise, this study aims to identify physiotherapists' experiences and determinants related to the usage...article 2020
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Tabasi, A. (author), Kingma, I. (author), de Looze, M.P. (author), van Dijk, W. (author), Koopman, A.S. (author), van Dieën, J.H. (author)Back support exoskeletons are designed to prevent work-related low-back pain by reducing mechanical loading. For actuated exoskeletons, support based on moments actively produced by the trunk muscles appears a viable approach. The moment can be estimated by a biomechanical model. However, one of the main challenges here is the feasibility of...article 2020
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Coenen, P. (author), Hulsegge, G. (author), Daams, J.G. (author), van Geenen, R.G. (author), Kerkhoffs, G.M. (author), van Tulder, M.W. (author), Huirne, J.A. (author), Anema, J.R. (author), Kuijser, P.P. (author)Objectives Orthopaedic surgery is primarily aimed at improving function and pain reduction. Additional integrated care may enhance patient’s participation in sports and work, possibly improving performance of physical activities and quality of life (QoL). We aimed to assess the effectiveness of integrated care among orthopaedic surgery patients....article 2020
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Huysamen, K. (author), de Looze, M.P. (author), Bosch, T. (author), Ortiz, J. (author), Toxin, S. (author), O'Sullivan, L.W. (author)The aim of this study was to evaluate the effect of an industrial exoskeleton on muscle activity, perceived musculoskeletal effort, measured and perceived contact pressure at the trunk, thighs and shoulders, and subjective usability for simple sagittal plane lifting and lowering conditions. Twelve male participants lifted and lowered a box of 7...article 2018
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Holden, M.A. (author), Burke, D.L. (author), Runhaar, J. (author), van der Windt, D. (author), Riley, R.D. (author), Dziedzic, K. (author), Legha, A. (author), Evans, A.L. (author), Abbott, J.H. (author), Baker, K. (author), Brown, J. (author), Bennell, K.L. (author), Bossen, D. (author), Brosseau, L. (author), Chaipinyo, K. (author), Christensen, R. (author), Cochrane, T, (author), de Rooij, M. (author), Doherty, M. (author), French, H.P. (author), Hickson, S. (author), Hinman, R.S. (author), Hopman-Rock, M. (author), Hurley, M.V. (author), Ingram, C. (author), Knoop, J. (author), Krauss, I., (author), McCarthy, C. (author), Messier, S.P. (author), Patrick, D.L. (author), Sahin, N. (author), Talbot, L.A. (author), Taylor, R. (author), Teirlinck, C.H. (author), van Middelkoop, M. (author), Walker, C. (author), Foster, N.E. (author)INTRODUCTION: Knee and hip osteoarthritis (OA) is a leading cause of disability worldwide. Therapeutic exercise is a recommended core treatment for people with knee and hip OA, however, the observed effect sizes for reducing pain and improving physical function are small to moderate. This may be due to insufficient targeting of exercise to...article 2017
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Anwar, I.B. (author), Saputra, E. (author), Ismail, R. (author), Jamari, J. (author), van der Heide, E. (author)Fixation of acetabular cup to bone material is an important initial stability for artificial hip joint. In general, the fixation in cement less-type acetabular cup uses press-fit and screw methods. These methods can be applied alone or together. Based on literature survey, the additional screw inside of cup is effective; however, it has little...conference paper 2016
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Saputra, E. (author), Anwar, I.B. (author), Ismail, R. (author), Jamari, J. (author), van der Heide, E. (author)Wear in the hip prosthesis due to sliding contact as a product of human activity is a phenomenon which cannot be avoided. In general, there are two modelof hip prostheses which are widely used in total hip replacement, i.e. unipolar and bipolar models. Wear in the bipolar model is more complex than the unipolar model due to its contact motion....conference paper 2016
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Differences in injury risk and characteristics between Dutch amateur and professional soccer playersvan Beijsterveldt, A.M.C. (author), Stubbe, J.H. (author), Schmikli, S.L. (author), van de Port, I.G.L. (author), Backx, F.J.G. (author)Objectives: To compare the incidence and characteristics of injuries between Dutch amateur and professional male soccer players during one entire competition season. Design: A prospective two-cohort design. Methods: During the 2009-2010 season, 456 Dutch male amateur soccer players and 217 professional players were prospectively followed....article 2015
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Elings, J. (author), Hoogeboom, T.J. (author), van der Sluis, G. (author), van Meeteren, N. (author)Objective: To identify the preoperative patient-related characteristics predicting inpatient recovery of functioning and/or length of hospital stay after elective primary total hip arthroplasty. Design: A search was conducted of the electronic databases MEDLINE, EMBASE and CINAHL from inception through April 2014. Observational studies were...article 2015
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Terhal, P.A. (author), Nievelstein, R.J.A.J. (author), Verver, E.J.J. (author), Topsakal, V. (author), van Dommelen, P. (author), Hoornaert, K. (author), le Merrer, M. (author), Zankl, A. (author), Simon, M.E. (author), Smithson, S.F. (author), Marcelis, C. (author), Kerr, B. (author), Clayton-Smith, J. (author), Kinning, E. (author), Mansour, S. (author), Elmslie, F. (author), Goodwin, L. (author), van der Hout, A.H. (author), Veenstra-Knol, H.E. (author), Herkert, J.C. (author), Lund, A.M. (author), Hennekam, R.C. (author), Mégarbané, A. (author), Lees, M.M. (author), Wilson, L.C. (author), Male, A. (author), Hurst, J. (author), Alanay, Y. (author), Annerén, G. (author), Betz, R.C. (author), Bongers, E.M. (author), Cormier-Daire, V. (author), Dieux, A. (author), David, A. (author), Elting, M.W. (author), van den Ende, J. (author), Green, A. (author), van Hagen, J.M. (author), Hertel, N.T. (author), Holder-Espinasse, M. (author), den Hollander, N. (author), Homfray, T. (author), Hove, H.D. (author), Price, S. (author), Raas-Rothschild, A. (author), Rohrbach, M. (author), Schroeter, B. (author), Suri, M. (author), Thompson, E.M. (author), Tobias, E.S. (author), Toutain, A. (author), Vreeburg, M. (author), Wakeling, E. (author), Knoers, N.V. (author), Coucke, P. (author), Mortier, G.R. (author)Type 2 collagen disorders encompass a diverse group of skeletal dysplasias that are commonly associated with orthopedic, ocular, and hearing problems. However, the frequency of many clinical features has never been determined. We retrospectively investigated the clinical, radiological, and genotypic data in a group of 93 patients with...article 2015
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de Lange-Brokaar, B.J.E. (author), Ioan-Facsinay, A. (author), van Osch, G.J.V.M. (author), Zuurmond, A.-M. (author), Schoones, J. (author), Toes, R.E.M. (author), Huizinga, T.W.J. (author), Kloppenburg, M. (author)Objective: Although osteoarthritis (OA) is considered a non-inflammatory condition, it is widely accepted that synovial inflammation is a feature of OA. However, the role of immune cells and their cytokines in OA is largely unknown. This narrative systematic review summarizes the knowledge of inflammatory properties, immune cells and their...article 2012
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Oosting, E. (author), Jans, M.P. (author), Dronkers, J.J. (author), Naber, R.H. (author), Dronkers-Landman, C.M. (author), Appelman-De Vries, S.M. (author), van Meeteren, N.L. (author)Preoperative home-based physical therapy versus usual care to improve functional health of frail older adults scheduled for elective total hip arthroplasty: a pilot randomized controlled trial. Objective: To investigate the feasibility and preliminary effectiveness of a home-based intensive exercise program to improve physical health of frail...article 2012
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Jans, M.P. (author), Slootweg, V.C. (author), Boot, C.R. (author), de Morton, N.A. (author), van der Sluis, G. (author), van Meeteren, N.L. (author)Objective: To examine the reproducibility, construct validity, and unidimensionality of the Dutch translation of the de Morton Mobility Index (DEMMI), a performance-based measure of mobility for older patients. Design: Cross-sectional study. Setting: Rehabilitation center (reproducibility study) and hospital (validity study). Participants:...article 2011
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Vos, P.A.J.M. (author), de Groot, J. (author), Huisman, A.M. (author), Oostveen, J.C.M. (author), Marijnissen, A.C.A. (author), Bijlsma, J.W.J. (author), van El, B. (author), Zuurmond, A.M. (author), Lafeber, F.P.J.G. (author), TNO Kwaliteit van Leven (author)Objectives: Age-related changes in articular cartilage are likely to play a role in the aetiology of osteoarthritis (OA). One of the major age-related changes in cartilage is the accumulation of advanced-glycation-endproducts (AGEs). Since, cartilage tissue is not readily available from patients for studying AGE levels, alternative approaches...article 2010
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van Spil, W.E. (author), de Groot, J. (author), Lems, W.F. (author), Oostveen, J.C.M. (author), Lafeber, F.P.J.G. (author), TNO Kwaliteit van Leven (author)Context: Molecules that are released into biological fluids during matrix metabolism of articular cartilage, subchondral bone, and synovial tissue could serve as biochemical markers of the process of osteoarthritis (OA). Unfortunately, actual breakthroughs in the biochemical OA marker field are limited so far. Objective: By reviewing the status...article 2010
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TNO Preventie en Gezondheid (author), Fleuren, M.A.H. (author), Dusseldorp, E. (author), van den Akker-van Marle, M.E. (author), van den Bergh-Verhappen, S. (author), Wildschut, J. (author), Vlek, H. (author), Wijkel, D. (author)Conference abstract of the 9th Annuale Integrated Care Conference, Vienna, Austria, 3-6 November 2009.article 2009
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Scharstuhl, A. (author), Schewe, B. (author), Benz, K. (author), Gaissmaier, C. (author), Bühring, H.J. (author), Stoop, R. (author), TNO Kwaliteit van Leven (author)Osteoarthritis (OA) is a multifactorial disease strongly correlated with history of joint trauma, joint dysplasia, and advanced age. Mesenchymal stem cells (MSCs) are promising cells for biological cartilage regeneration. Conflicting data have been published concerning the availability of MSCs from the iliac crest, depending on age and overall...article 2007
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Meulenbelt, I. (author), Kloppenburg, M. (author), Kroon, H.M. (author), Houwing-Duistermaat, J.J. (author), Garnero, P. (author), Hellio-Le Graverand, M.-P. (author), de Groot, J. (author), Slagboom, P.E. (author), TNO Kwaliteit van Leven (author)Objective: To assess the relationship of biochemical markers and radiographic signs of osteoarthritis (ROA) in the subjects with symptomatic osteoarthritis (OA) at multiple sites of the Genetics osteoARthritis and Progression (GARP) study. Methods: We have measured eight biochemical markers, representing tissue turnover of cartilage, bone,...article 2007
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TNO Kwaliteit van Leven (author), Meulenbelt, I. (author), Kloppenburg, M. (author), Kroon, H.M. (author), Houwing-Duistermaat, J.J. (author), Garnero, P. (author), Hellio Le Graverand, M.P. (author), de Groot, J. (author), Slagboom, P.E. (author)Objective: To assess the relation between the urinary concentrations of type II collagen C-telopeptide (UCTX-II) and radiographie signs of osteoarthritis (ROA) in the GARP (Genetics, Arthrosis and Progression) study. Methods: UCTX-II levels were measured in GARP study participants, who are sibling pairs predominantly with symptomatic...article 2006