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- Meima, M.Y. (author), Blom, W.M. (author), Westerhout, J. (author), Kruizinga, A.G. (author), Remington, B.C. (author), Wheeler, M.W. (author), Houben, G.F. (author) article 2021
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Meima, M.Y. (author), Remington, B.C. (author), Blom, W.M. (author), Baumert, J.L. (author), Taylor, S.L. (author), Jeffery, B. (author), Robert, M.C. (author), Houben, G.F. (author), Lucas Luijckx, N.B. (author)Allergenic food particles (typically ~0.5–5 mm) may unintentionally end up in food products during production and can pose a risk for the allergic consumer. A single particle can provoke allergic symptoms in an allergic consumer when the dose of allergenic protein exceeds minimal eliciting doses. However, there is a lack of fundamental knowledge...article 2021
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Remington, B.C. (author), Westerhout, J. (author), Dubois, A.E.J. (author), Blom, W.M. (author), Kruizinga, A.G. (author), Taylor, S.L. (author), Houben, G.F. (author), Baumert, J.L. (author)Food allergen threshold dose distributions are used in food allergen risk assessment to determine the level of risk within a food-allergic population to a defined exposure amount of allergenic food protein and to help inform allergen risk management decisions. There has been a long-standing interest in determining threshold dose distributions...article 2021
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A well-functioning immune system is critical for adequate responses to daily life health challenges such as infections. But at the same time, overshooting immune responses may lead to allergic and inflammatory diseases. Our immune balances are determined by a complex interplay between intrinsic properties such as our genome, and extrinsic...other 2021
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Are you concerned about allergenic proteins in food products that your company produces or provides? TNO offers a solid research and expertise base that we commit to developing practical solutions for food business operators. By quantification of allergen risks and support in allergen management, we help you to deliver safe products for allergic...other 2021
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Smits, M. (author), Nooijen, I. (author), Redegeld, F. (author), de Jong, A. (author), Le, T.M. (author), Knulst, A. (author), Houben, G.F. (author), Verhoeckc, K.C.M. (author)Scope: No accepted and validated methods are currently available which can accurately predict protein allergenicity. In this study, the role of digestion and transport on protein allergenicity is investigated. Methods and results: Peanut allergens (Ara h 1, 2, 3, and 6) and a milk allergen (β-lactoglobulin) are transported across pig intestinal...article 2021
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Fluitman, K.S. (author), Hesp, A.C. (author), Kaihatu, R.F. (author), Nieuwdorp, M. (author), Keijser, B.J.F. (author), IJzerman, R.G. (author), Visser, M. (author)BACKGROUND: Age-related declines in taste and smell function are widely assumed to contribute to the decrease in appetite and the development of undernutrition in older adults. OBJECTIVES: Here we aim to assess the associations of both taste and smell function with several nutrition-related outcomes in a single study, with poor appetite and...article 2021
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Smits, M. (author), Meijerink, M. (author), Le, T.M. (author), Knulst, A. (author), de Jong, A. (author), Caspers, M.P.M. (author), Lima, E.S. (author), Babe, L. (author), Ladics, G. (author), McClain, S. (author), Houben, G.F. (author), Verhoeckx, K. (author)Background: Food proteins differ in their allergenic potential. Currently, there is no predictive and validated bio-assay to evaluate the allergenicity of novel food proteins. The objective of this study was to investigate the potential of a human peripheral blood mononuclear cell (PBMC) gene expression assay to identify biomarkers to predict...article 2021
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Butler, F. (author), Lucas Luijckx, N.B. (author), Marvin, H.J.P. (author), Bouzembrak, Y. (author), Mojtahed, V. (author)Food fraud is of high concern to the food industry. A multitude of analytical technologies exist to detect fraud. However, this testing is often expensive. Available databases detailing fraud occurrences were systematically examined to determine how frequently analytical testing triggered fraud detection. A conceptual framework was developed for...article 2021
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Brouwer, A.M. (author), van Beers, J.J. (author), Sabu, P. (author), Stuldreher, I.V. (author), Zech, H.G. (author), Kaneko, D. (author)Implicit (‘unconscious’) approach–avoidance tendencies towards stimuli can be measured using the Approach Avoidance Task (AAT). We recently expanded a toolbox for analyzing the raw data of a novel, mobile version of the AAT (mAAT), that asks participants to move their phone towards their face (pull) or away (push) in response to images presented...article 2021
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Derossi, A. (author), Bhandari, B. (author), van Bommel, K. (author), Noort, M. (author), Severini, C. (author)The ongoing COVID-19 pandemic is having a tremendous effect on the current food system. The situation urges us to face many issues never experienced before, aimed at mitigating a multitude of sanitary and social risks. The current pandemic has affected the food system in many ways: significant changes in dietary habits and in the health status...article 2021
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- Versluis, A. (author), Knulst, A.C. (author), Michelsen-Huisman, A.D. (author), Houben, G.F. (author), Blom, W.M. (author), Le, T.M. (author), van Os-Medendorp, H. (author) article 2021
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Every food producer knows the importance of allergen risk assessment and management in view of well-known allergens, such as those from peanut, egg and milk. However, all proteins intrinsically come with a risk of being allergenic. Therefore, safety assessment for protein-based food products needs to address potential allergenicity risks. This...other 2021
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van der Burg, E. (author), Toet, A. (author), Abbasi, Z. (author), Brouwer, A.M. (author), van Erp, J.B.F. (author), Kallen, V.L. (author), Kaneko, D. (author), Kim, Y. (author), Kinnear, M. (author), de Kock, H.L. (author), Kusbiantari, D. (author), Lee, T.R. (author), Liu, Y. (author), Luhovyy, B.L. (author), MacEachern, E. (author), Mezgebe, A.G. (author), Nikolova, R. (author), Olatunde, G. (author), Srisayekti, W. (author), Rizwan Tahir, M. (author), Ushiama, S. (author), Yürek, M.E. (author)How we perceive the world is not solely determined by our experiences at a given moment in time, but also by what we have experienced in our immediate past. Here, we investigated whether such sequential effects influence the affective appraisal of food images. Participants from 16 different countries (N = 1278) watched a randomly presented...article 2021
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Fluitman, K.S. (author), van den Broek, T.J. (author), Nieuwdorp, M. (author), Visser, M. (author), IJzerman, R.G. (author), Keijser, B.J.F. (author)Poor taste and smell function are widely thought to contribute to the development of poor appetite and undernutrition in older adults. It has been hypothesized that the oral microbiota play a role as well, but evidence is scarce. In a cross-sectional cohort of 356 older adults, we performed taste and smell tests, collected anthropometric...article 2021
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Zhang, L. (author), Noort, M. (author), van Bommel, K. (author)Bakery products with interesting color, shape and texture have been created using 3D food printing. Current research focuses on the development of new formulations and the optimization of the printing and post-printing treatment processes, in order to obtain high-quality 3D-printed bakery products. Knowledge about food rheology is useful for the...bookPart 2021
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Patel, N. (author), Adelman, D.C. (author), Anagnostou, K. (author), Baumert, J.L. (author), Blom, W.M. (author), Campbell, D.E. (author), Chinthrajah, R.S. (author), Mills, E.N.C. (author), Javed, B. (author), Purington, N. (author), Remington, B.C. (author), Sampson, H.A. (author), Smith, A.D. (author), Yarham, R.A.R. (author), Turner, P.J. (author)Background Eliciting doses (EDs) (eg, ED01 or ED05 values, which are the amounts of allergen expected to cause objective symptoms in 1% and 5% of the population with an allergy, respectively) are increasingly being used to inform allergen labeling and clinical management. These values are generated from food challenge, but the frequency of...article 2021
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Blom, W.M. (author), van Dijk, L.M. (author), Michelsen-Huisman, A. (author), Houben, G.F. (author), Knulst, A.C. (author), Linders, Y.F.M. (author), Verhoeckc, K.C.M. (author), Holleman, B.C. (author), Lentz, L.R. (author)Background: Allergen information on product labels is crucial in food allergy management, though inadequacy in current labelling practices is one of the major causes for accidental reactions upon consuming prepacked food products. Objective: This study analyses current status of communicating allergen information on food labels and provides...article 2021
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Remington, B.C. (author), Westerhout, J. (author), Meima, M.Y. (author), Blom, W.M. (author), Kruizinga, A.G. (author), Wheeler, M.W. (author), Taylor, S.L. (author), Houben, G.F. (author), Baumert, J.L. (author)Food allergy and allergen management are important global public health issues. In 2011, the first iteration of our allergen threshold database (ATDB) was established based on individual NOAELs and LOAELs from oral food challenge in roughly 1750 allergic individuals. Population minimal eliciting dose (EDp) distributions based on this dataset...article 2020
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van Beers, J.J. (author), Kaneko, D. (author), Stuldreher, I.V. (author), Zech, H.G. (author), Brouwer, A.M. (author)Implicit approach-avoidance tendencies can be measured by the approach-avoidance task (AAT). The emergence of mobile variants of the AAT enable its use for both in-the-lab and in-the-field experiments. Within the food domain, use of the AAT is concentrated in research on eating disorders or healthy eating and is seldom used as an implicit...conference paper 2020