Searched for: subject%3A%22exposure%22
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de Mooij, B. (author), Fekkes, M (author), Miers, A.C. (author), van den Akker, A.L. (author), Scholte, R.H.J. (author), Overbeek, G. (author)
Programs that aim to reduce symptoms of social anxiety in children generally include multiple components, such as exposure and cognitive restructuring. It is unknown if separate components yield positive intervention effects in children or whether a combination of components is required. We investigated the effectiveness of exposure, cognitive...
article 2023
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Rhodes, S. (author), Beale, S. (author), Wilkinson, J. (author), van Veldhoven, K. (author), Basinas, J. (author), Mueller, W. (author), Oude Hengel, K.M. (author), Burdorf, A. (author), Peters, S. (author), Stokholm, Z.A. (author), Schlünssen, V. (author), Kolstad, H. (author), Pronk, A. (author), Pearce, N. (author), Hayward, A. (author), van Tongeren, M. (author)
Objective: This study aimed to assess whether workplace exposures as estimated via a COVID-19 job exposure matrix (JEM) are associated with SARS-CoV-2 in the UK. Methods: Data on 244 470 participants were available from the Office for National Statistics Coronavirus Infection Survey (CIS) and 16 801 participants from the Virus Watch Cohort,...
article 2022
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Heus, R. (author), van Berlo, M.P.W. (author), van Berlo, B.M.A. (author), Mol, D. (author), Daanen, H.A.M. (author), Kuklane, K. (author)
During the early stage of a fire, a process operator often acts as the first responder and may be exposed to high heat radiation levels. The present limit values of long- (>15 min) and short-term exposure (
article 2022
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Scholten, B. (author), Portengen, L. (author), Pronk, A. (author), Stierum, R. (author), Downward, G.S. (author), Vlaanderen, J. (author), Vermeulen, R. (author)
Background: Chemical risk assessment can benefit from integrating data across multiple evidence bases, especially in exposure–response curve (ERC) modeling when data across the exposure range are sparse. Methods: We estimated the ERC for benzene and acute myeloid leukemia (AML), by fitting linear and spline-based Bayesian meta-regression models...
article 2022
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Fransman, W. (author), Otten, W. (author), Marquart, H. (author), Preuhs, K. (author), Willemsen, J. (author), Boumann, H. (author), Gerritsen, R. (author)
Objectives: Within the chemical legislation, REACH was implemented in order to improve safe working conditions with hazardous substances. Literature and real-life experiences by those concerned have shown that there are still gaps with a need for improved risk communication. This study elaborated on how information provided by REACH is...
article 2022
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Oude Hengel, K.M. (author), Burdorf, A. (author), Pronk, A. (author), Schlünssen, V. (author), Stokholm, Z.A. (author), Kolstad, H.A. (author), van Veldhoven, K. (author), Basinas, I. (author), van Tongeren, M. (author), Peters, S. (author)
Objective This study aimed to construct a job exposure matrix (JEM) for risk of becoming infected with the SARS-CoV-2 virus in an occupational setting. Methods Experts in occupational epidemiology from three European countries (Denmark, The Netherlands and the United Kingdom) defined the relevant exposure and workplace characteristics with...
article 2022
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Traversari, A.A.L. (author), Bezemer, R.A. (author), van Heumen, S.P.M. (author), Kompatscher, K. (author), Hinkema, M.J. (author), Eekhout, I. (author)
Social distancing measures to lower the risk of SARS-CoV-2 transmission limit seating capacity in and constrain restaurants’ ability to operate in an economically sustainable way. Experiments have been conducted in a real-size mock-up of a restaurant, using different table setting and configurations of the ventilation system. The study has...
article 2022
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Pronk, A. (author), Loh, M. (author), Kuijpers, E. (author), Albin, M. (author), Selander, J. (author), Godderis, L. (author), Ghosh, M. (author), Vermeulen, R. (author), Peters, S. (author), Sivesind Mehlum, I. (author), Turner, M. (author), Schlunssen, V. (author), Goldberg, M. (author), Kogevinas, M. (author), Harding, B. (author), Solovieva, S. (author), Garani-Papadatos, T. (author), van Tongeren, M. (author), Stierum, R. (author)
Exposures at work have a major impact on noncommunicable diseases (NCDs). Current risk reduction policies and strategies are informed by existing scientific evidence, which is limited due to the challenges of studying the complex relationship between exposure at work and outside work and health. We define the working life exposome as all...
article 2022
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Bongers, C.C.W.G. (author), de Korte, J.Q. (author), Zwartkruis, M. (author), Levels, K. (author), Kingma, B.R.M. (author), Eijsvogels, T.M.H. (author)
The combination of an exacerbated workload and impermeable nature of the personal protective equipment (PPE) worn by COVID-19 healthcare workers increases heat strain. We aimed to compare the prevalence of heat strain symptoms before (routine care without PPE) versus during the COVID-19 pandemic (COVID-19 care with PPE), identify risk factors...
article 2022
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Tsakirakis, A.N. (author), Kasiotis, K.M. (author), Glass, R.C. (author), Charistou, A.N. (author), Anastasiadou, P. (author), Gerritsen-Ebben, R.M. (author), Machera, K. (author)
Dermal transfer of pesticide residues to human skin due to contact with treated crops, treated surfaces, or contaminated surfaces is an important route of exposure for operators, workers and possibly for bystanders and residents. However, information on dermal transfer data is limited and mainly available for workers. The aim of the present...
article 2022
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Fransman, W. (author), Arnone, M. (author), Borghi, F. (author), Cattaneo, A. (author), Cavallo, D.M. (author), Cherrie, J.W. (author), Franken, R. (author), Galea, K.S. (author), van der Haar, R. (author), Heussen, G.A.H. (author), Jensen, K.A. (author), Koponen, M. (author), Koppisch, D. (author), Kromhout, H. (author), Luo, KY.S. (author), McNally, K. (author), Säämänen, A. (author), Spinazzè, A. (author), van Tongeren, M. (author), Jeroen, (author), Vanoirbeek, J. (author), Verpaele, S. (author), Vetter, D. (author), Viegas, S. (author), Warren, N. (author)
In this article, we have responded to the key statements in the article by Koivisto et al. (2022) that were incorrect and considered to be a biased critique on a subset of the exposure models used in Europe (i.e. ART and Stoffenmanager®) used for regulatory exposure assessment. We welcome scientific discussions on exposure modelling (as was done...
article 2022
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van der Feltz, S. (author), Peters, S. (author), Pronk, A. (author), Schlünssen, V. (author), Stokholm, Z.A. (author), Kolstad, H.A. (author), van Veldhoven, K. (author), Basinas, I. (author), van Tongeren, M. (author), Burdorf, A. (author), Oude Hengel, K.M. (author)
Objectives A COVID-19 Job Exposure Matrix (COVID-19-JEM) has been developed, consisting of four dimensions on transmission, two on mitigation measures, and two on precarious work. This study aims to validate the COVID-19-JEM by (i) comparing risk scores assigned by the COVID-19-JEM with self-reported data, and (ii) estimating the associations...
article 2022
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Huuskonen, P. (author), Karakitsios, S. (author), Scholten, B. (author), Westerhout, J. (author), Sarigiannis, D.A. (author), Santonen, T. (author)
The aim of this work was to demonstrate how human biomonitoring (HBM) data can be used to assess cancer risks for workers and the general population. Ortho-toluidine, OT (CAS 95-53-4) is an aniline derivative which is an animal and human carcinogen and may cause methemoglobinemia. OT is used as a curing agent in epoxy resins and as intermediate...
article 2022
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McNally, K. (author), Goede, H.A. (author), Schinkel, J. (author), Gorce, J.P. (author), Warren, N. (author)
The dermal Advanced REACH Tool (dART) is a tier 2 exposure model for estimating dermal exposure to the hands (mg min-1) for non-volatile liquid and solid-in-liquid products. The dART builds upon the existing ART framework and describes three mass transport processes (deposition (Dhands), direct emission and direct contact (Ehands), and contact...
article 2022
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Schlüter, U. (author), Arnold, S. (author), Borghi, F. (author), Cherrie, J. (author), Fransman, W. (author), Heussen, H. (author), Jayjock, M. (author), Jensen, K.A. (author), Koivisto, J. (author), Koppisch, D. (author), Meyer, J. (author), Spinazzè, A. (author), Tanarro, C. (author), Verpaele, S. (author), von Goetz, N. (author)
On 20 October 2020, the Working Group “Exposure Models” of the Europe Regional Chapter of the International Society of Exposure Science (ISES Europe) organised an online workshop to discuss the theoretical background of models for the assessment of occupational exposure to chemicals. In this report, participants of the workshop with an active...
article 2022
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von Benda-Beckmann, A.M. (author), Ketten, D.R. (author), Lam, F.P.A. (author), de Jong, C.A.F. (author), Muller, R.A.J. (author), Kastelein, R.A. (author)
Application of a kurtosis correction to frequency-weighted sound exposure level (SEL) improved predictions of risk of hearing damage in humans and terrestrial mammals for sound exposures with different degrees of impulsiveness. To assess whether kurtosis corrections may lead to improved predictions for marine mammals, corrections were applied to...
article 2022
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Figueiredo, D.M. (author), Nijssen, R. (author), Krop, E.J.M. (author), Buijtenhuijs, D. (author), Gooijer, Y. (author), Lageschaar, L. (author), Duyzer, J. (author), Huss, A. (author), Mol, H. (author), Vermeulen, R.C.H. (author)
Indoor dust has been postulated as an important matrix for residential pesticide exposure. However, there is a lack of information on presence, concentrations and determinants of multiple pesticides in dust in residential homes close to treated fields. Our objective was to characterize the spatial and temporal variance of pesticides in house...
article 2022
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Schlüter, U. (author), Meyer, J. (author), Ahrens, A. (author), Borghi, F. (author), Clerc, F. (author), Delmaar, C. (author), Di Guardo, A. (author), Dudzina, T. (author), Fantke, P. (author), Fransman, W. (author), Hahn, S. (author), Heussen, H. (author), Jung, C. (author), Koivisto, J. (author), Koppisch, D. (author), Paini, A. (author), Savic, N. (author), Spinazzè, A. (author), Jeddi, M.Z. (author), von Goetz, N. (author)
Exposure models are essential in almost all relevant contexts for exposure science. To address the numerous challenges and gaps that exist, exposure modelling is one of the priority areas of the European Exposure Science Strategy developed by the European Chapter of the International Society of Exposure Science (ISES Europe). A strategy was...
article 2022
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Otten, W. (author), Marquart, H. (author), Preuhs, K. (author), Willemsen, J. (author), Boumann, H. (author), Gerritsen, R. (author), Fransman, W. (author)
Presently, there is a lack of knowledge on the effectiveness of the information exchange on safe use conditions up and down the supply chain. The aim of the present research project CEFIC LRI B23 was to provide a substantial contribution to the knowledge needed to optimize information exchange on safe use conditions, specifically under REACH....
report 2022
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Jones, K. (author), Galea, K.S. (author), Scholten, B. (author), Porras, S. (author), Bousoumah, R. (author), Ndaw, S. (author), Louro, H. (author), Silva, M.J. (author), Viegas, S. (author), Godderis, L. (author), Verdonck, J. (author), Poels, K. (author), Groen, T. (author), Duca, R.C. (author), Santonen, T. (author), HBM4EU Diisocyanates Study Team, (author)
Diisocyanates have long been a leading cause of occupational asthma in Europe, and recently, they have been subjected to a restriction under the REACH regulations. As part of the European Human Biomonitoring project (HBM4EU), we present a study protocol designed to assess occupational exposure to diisocyanates in five European countries. The...
article 2022
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