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Rovida, C. (author), Escher, S.E. (author), Herzler, M. (author), Bennekou, S.H. (author), Kamp, H. (author), Kroese, D.E. (author), Maslankiewicz, L. (author), Moné, M.J. (author), Patlewicz, G. (author), Sipes, N. (author), van Aerts, L. (author), White, A. (author), Yamada, T. (author), van de Water, B. (author)The use of new approach methodologies (NAMs) in support of read-across (RAx) approaches for regulatory purposes is a main goal of the EU-ToxRisk project. To bring this forward, EU-ToxRisk partners convened a workshop in close collaboration with regulatory representatives from key organizations including European regulatory agencies, such as the...article 2021
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Kim, C. (author), Colborn, K. (author), van Buuren, S. (author), Loar, T. (author), Stevens-Lapsley, J.E. (author), Kittelson, A.J. (author)The purpose of this study was to develop and test personalized predictions for functional recovery after Total Knee Arthroplasty (TKA) surgery, using a novel neighbors-based prediction approach. We used data from 397 patients with TKA to develop the prediction methodology and then tested the predictions in a temporally distinct sample of 202...article 2021
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- Mehta, R. (author), Golkaram, M. (author) public lecture 2021
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- Mehta, R. (author), Golkaram, M. (author) other 2021
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de Gelder, E. (author), Elrofai, H. (author), Saberi, A.K. (author), Paardekooper, J.-P. (author), Op Den Camp, O. (author), de Schutter, B. (author)The development of safety validation methods is essential for the safe deployment and operation of Automated Driving Systems (ADSs). One of the goals of safety validation is to prospectively evaluate the risk of an ADS dealing with real-world traffic. ISO 26262 and ISO/DIS 21448, the leading standards in automotive safety, provide an approach to...article 2021
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van der Waa, J. (author), Nieuwburg, E. (author), Cremers, A. (author), Neerincx, M. (author)Current developments in Artificial Intelligence (AI) led to a resurgence of Explainable AI (XAI). New methods are being researched to obtain information from AI systems in order to generate explanations for their output. However, there is an overall lack of valid and reliable evaluations of the effects on users' experience of, and behavior in...article 2021
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Hogervorst, M.A. (author), de Kok, M.M. (author)Within the EDA funded project ACAMSII, "Adaptive camouflage for the soldier", a future soldier system is being developed and implemented that provides adaptive camouflage against all relevant sensor threats, ranging from visible to thermal and radar. To provide adaptive camouflage in the visible domain LEDs are integrated in the clothing. A...conference paper 2021
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Grappiolo, C. (author), Pruim, R. (author), Faeth, M. (author), de Heer, P.B.U.L. (author)Product customisation is a topic of growing interest in Smart Manufacturing. Allowing customers to design intended products brings additional challenges to the manufacturing task, such as the increase in flexibility of the assembly theatre, the compilation of assembly instructions for possibly unique products, and stress-related risks for human...article 2021
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Kleinrouweler, J.W. (author), Potetsianakis, E. (author), D'Acunto, L. (author)This paper presents the design and evaluation of a localized crowd-sourced multimedia production and distribution system to enable today's mobile producers of multimedia content to serve their content in real-time to other nearby users, while at the same time drastically reducing the bandwidth as compared to traditional crowd-sourced multimedia...conference paper 2020
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Franken, R.A. (author), Kasiotis, K.M. (author), Tsakirakis, A.N. (author), Chartzela, I. (author), Anastasiadou, P. (author), Fransman, W. (author), Gerritsen-Ebben, R.M. (author), Spaan, S. (author), Goede, H. (author), Machera, K. (author), Gerritsen-Ebben, R. (author)For many work situations only insufficient exposure data are available to perform proper risk assessment. Because measuring worker exposure can be time consuming and resource intense, the availability of reliable exposure models is important when performing risk assessments. However, the development and improvement of exposure models are...article 2020
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- Gilsing, R. (author), Turetken, O. (author), Ozkan, B. (author), Slaats, F. (author), Adali, O.E. (author), Wilbik, A. (author), Berkers, F.T.H.M (author), Grefen, P. (author) conference paper 2020
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Rijnaarts, I. (author), de Roos, N.M. (author), Wang, T. (author), Zoetendal, E.G. (author), Top, J. (author), Timmer, M. (author), Bouwman, E.P. (author), Hogenelst, K. (author), Witteman, B. (author), de Wit, N. (author)Objective: A high-fibre diet is associated with a lower risk for diseases. However, few adults meet the dietary fibre recommendation. Therefore, the effects and acceptance of an algorithm-generated personalised dietary advice (PDA) compared with general advice (GA) on fibre intake were investigated. Design: A 6-week, single-blind randomised...article 2020
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Vazquez, A.R. (author), Goos, P. (author), Schoen, E.D. (author)Definitive screening designs permit the study of many quantitative factors in a few runs more than twice the number of factors. In practical applications, researchers often require a design for m quantitative factors, construct a definitive screening design for more than m factors and drop the superfluous columns. This is done when the number of...article 2020
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Cherrie, J.W. (author), Fransman, W. (author), Heussen, G.A.H. (author), Koppisch, D. (author), Jensen, K.A. (author)Model tools for estimating hazardous substance exposure are an accepted part of regulatory risk assessments in Europe, and models underpin control banding tools used to help manage chemicals in workplaces. Of necessity the models are simplified abstractions of real-life working situations that aim to capture the essence of the scenario to give...article 2020
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Franken, R. (author), Shandilya, N. (author), Marquart, H. (author), McNally, K. (author), Fransman, W. (author)Measured data are generally preferred to modelled estimates of exposure. Grouping and read-across is already widely used and accepted approach in toxicology, but an appropriate approach and guidance on how to use existing exposure measurement data on one substance and work situation for another substance and/or work situation is currently not...article 2020
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Koopman, A.S. (author), Naf, M. (author), Baltrusch, S.J. (author), Kingma, I. (author), Rodriguez-Guerrero, C. (author), Babic, J. (author), de Looze, M.P. (author), van Dieën, J.H. (author)The number one cause of disability in the world is low-back pain, with mechanical loading as one of the major risk factors. To reduce mechanical loading, exoskeletons have been introduced in the workplace. Substantial reductions in back muscle activity were found when using the exoskeleton during static bending and manual materials handling....article 2020
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Cacciatore, P. (author), Visser, L.A. (author), Buyukkaramikli, N. (author), van der Ploeg, C.P.B. (author), van den Akker-van Marle, M.E. (author)Introduction: Cost-effectiveness (CEA) and cost–utility analyses (CUA) have become popular types of economic evaluations (EE) used for evidence-based decision-making in healthcare resource allocation. Newborn screening programs (NBS) can have significant clinical benefits for society, and cost-effectiveness analysis may help to select the...article 2020
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Ruiter, S. (author), Kuijpers, E. (author), Saunders, J. (author), Snawder, J. (author), Warren, N. (author), Gorce, J.P. (author), Blom, M. (author), Krone, T. (author), Bard, D. (author), Pronk, A. (author), Cauda, E. (author)Background: Small, lightweight, low-cost optical particulate matter (PM) monitors are becoming popular in the field of occupational exposure monitoring, because these devices allow for real-time static measurements to be collected at multiple locations throughout a work site as well as being used as wearables providing personal exposure...article 2020
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Pot, M. (author), Paulussen, T.G. (author), Ruiter, R.A. (author), Hofstra, M. (author), van Keulen, H.M. (author)Background: In the Netherlands, human papillomavirus (HPV) vaccination uptake remains low. To improve informed decision making (IDM) and HPV vaccination acceptability, we systematically developed an interactive, web-based tailored intervention to which mothers of Dutch girls were invited to participate. Objective: The aim of this study was to...article 2020
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Schweiker, M. (author), Andréu, M. (author), Al-Atrash, F. (author), Al-Khatri, H. (author), Alprianti, R.R. (author), Alsaad, H. (author), Amin, R. (author), Ampatzi, E. (author), Arsano, A.Y. (author), Azar, E. (author), Bannazadeh, B. (author), Batagarawa, A. (author), Becker, S. (author), Buonocore, C. (author), Cao, B. (author), Choi, J.H. (author), Chun, C. (author), Daanen, H.A.M. (author), Damiati, S.A. (author), Daniel, L. (author), de Vecchi, R. (author), Dhaka, S. (author), Domínguez-Amarillo, S. (author), Dudkiewicz, E. (author), Edappilly, L.P. (author), Fernández-Agüera, J. (author), Folkerts, M. (author), Frijns, A. (author), Gaona, G. (author), Garg, V. (author), Gauthier, S. (author), Ghaffari Jabbari, S. (author), Harimi, D. (author), Hellwig, R.T. (author), Huebner, G.M. (author), Jin, Q. (author), Jowkar, M. (author), Kim, K. (author), King, N. (author), Kingma, B.R.M. (author), Koerniawan, M.D. (author), Kolarik, J. (author), Kumar, S. (author), Kwok, A. (author), Lamberts, R. (author), Laska, M. (author), Lee, M.C.J. (author), Lee, Y. (author), Lindermayr, V. (author), Mahaki, M. (author), Marcel-Okafor, U. (author), Marín-Restrepo, L. (author), Marquardsen, A. (author), Martellotta, F. (author), Mathur, J. (author), Mino-Rodriguez, I. (author), Montazami, A. (author), Mou, D. (author), Moujalled, B. (author), Nakajima, M. (author), Ng, E. (author), Okafor, M. (author), Olweny, M. (author), Ouyang, W. (author), Lígia Papst de Abreu, A. (author), Pérez-Fargallo, A. (author), Rajapaksha, I. (author), Ramos, G. (author), Rashid, S. (author), Reinhart, C.F. (author), Rivera, I.M. (author), Salmanzadeh, M. (author), Schakib-Ekbatan, K. (author), Schiavon, S. (author), Shooshtarian, S. (author), Shukuya, M. (author), Soebarto, V. (author), Suhendri, S. (author), Tahsildoost, M. (author), Tartarini, F. (author), Teli, D. (author), Tewari, P. (author), Thapa, S. (author), Trebilcock, M. (author), Trojan, J. (author), Tukur, R.B. (author), Voelker, C. (author), Yam, Y. (author), Yang, L. (author), Zapata-Lancaster, G. (author), Zhai, Y. (author), Zhu, Y. (author), Zomorodian, Z. (author)People's subjective response to any thermal environment is commonly investigated by using rating scales describing the degree of thermal sensation, comfort, and acceptability. Subsequent analyses of results collected in this way rely on the assumption that specific distances between verbal anchors placed on the scale exist and that relationships...article 2020