Selenium in diet, blood, and toenails in relation to breast cancer: A case-control study

The association between breast cancer and selenium, measured in the diet, plasma, erythrocytes, and toenails, was investigated in a case-control study in the Netherlands during 1985-1987. Dietary selenium intake was assessed by a structured dietary history technique among 133 breast cancer cases and 238 population controls. Absolute and energy...

Vitamin B6 status of women suffering from premenstrual syndrome

The vitamin B6 status of women suffering from premenstrual symptoms (PMS, n = 19) and a group of matched controls (n = 19) has been investigated. The women volunteering in the study were selected on strictly defined criteria. Several biochemical parameters of the metabolism of vitamin B6 and tryptophan were studied in blood and urine samples...

Glucagon receptors: Are they present on human blood cells?

Binding of glucagon to and its degradation by human mononuclear leukocytes and erythrocytes was investigated. Labeled glucagon binds to these cells, but can be displaced only by unlabeled glucagon at pharmacologically high concentrations. It is concluded that glucagon binding to human blood cells does not represent receptors of physiological...

The effect of irradiation on the antibody enhancing helper T cells

Helper T cells specific for sheep erythrocytes were generated in lethally irradiated mice. The helper effect exerted by these cells was determined in vitro in spleen cell cultures. Irradiation of the helper cells in vivo or in vitro with 1-9 Gy resulted in a bimodal relation between radiation dose and helper effect when measured either...

Absence of an effect of lead acetate on sperm morphology, sister chromatid exchanges or on micronuclei formation in rabbits

The influence of lead on sperm morphology, sister chromatid exchanges or on micronuclei formation was studied on male rabbits after exposure to doses of 0, 0.25, and 0.50 mg lead acetate/kg body weight subcutaneously injected three times a week during 14 weeks, each on a group of five rabbits. At the end of exposure phase the lead in blood...

Short term inhalation toxicity studies with peroxyacetyl nitrate in rats

The inhalation toxicity of peroxyacetyl nitrate (PAN) was examined in acute (single exposure), subacute (4-wk repeated exposure) and subchronic (13-wk repeated exposure) studies in rats. The 4-hr LC50 was found to be 95 ppm. In the 4-wk study rats were exposed to 0, 0.9, 4.1 or 11.8 ppm PAN vapor for 6 hr/day, 5 days/wk. Exposure to 11.8 ppm...

Isolation of antibody forming cells by using cluster formation in combination with velocity sedimentation

A method is described for isolation of antibody forming cells with the help of cluster formation. This was achieved by incubating spleen cells from immunized mice with sheep erythrocytes at 37°C. During incubation rabbit anti mouse immunoglobulin serum was present in order to facilitate the formation of clusters. Thereafter the clusters were...

Nutritional effects of alkali treated soyprotein in rats

Alkali treated spun soy isolate was fed to rats at dietary levels of 5, 10, and 20% for a period of 90 days. The results failed to reveal any adverse effects on general appearance, growth, feeding efficiency, hematological indices, blood serum values, urine composition, kidney function, organ weights, and gross and microscopic pathology except...

Safety evaluation of yeast grown on hydrocarbons. II: One-year feeding study in rats with yeast grown on pure n-paraffins

Yeast grown on hydrocarbons according to the n-paraffin process of The British Petroleum Company Ltd. was fed to groups of male and female rats at dietary levels of 10, 20 and 30% for 1 yr. Two control diets were used, one being similar to the yeast diet but with soya-bean meal substituted for yeast and the other being the institute's stock diet...

Growth inhibition of bacteria by tributylgermanium acetate and its reversal by blood constituents

Growth inhibition of Mycobacterium phlei by tributylgermanium acetate can be reversed by addition of large amounts of blood or blood serum to the nutrient medium; the blood erythrocyte fraction is inactive. On the other hand growth inhibition of the lactic acid bacteria Streptococcus lactis and Leuconostoc mesenteroides can be counteracted by...

Aneurin-pyrophosphate content of red and white blood corpuscles in the rat and in man

[No abstract available]