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Gayban, A.J.B. (author), Souza, L.A.C. (author), Cooper, S.G. (author), Regalado, E. (author), Kleemann, R. (author), Earley, Y.F. (author)Non-alcoholic fatty liver disease (NAFLD) comprises a spectrum of liver damage directly related to diabetes, obesity, and metabolic syndrome. The (pro)renin receptor (PRR) has recently been demonstrated to play a role in glucose and lipid metabolism. Here, we test the hypothesis that the PRR regulates the development of diet-induced hepatic...article 2023
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Piedvache, A. (author), van Buuren, S. (author), Barros, H. (author), Ribeiro, A.I. (author), Draper, E. (author), Zeitlin, J. (author), EPICE Research group, (author)Background: Loss to follow-up is a major challenge for very preterm (VPT) cohorts; attrition is associated with social disadvantage and parents with impaired children may participate less in research. We investigated the impact of loss to follow-up on the estimated prevalence of neurodevelopmental impairment in a VPT cohort using different...article 2021
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Li Piani, T. (author), Weerheijm, J. (author), Koene, L. (author), Sluys, L.J. (author)A local damage model is proposed for the numerical assessment of the static performance of Adobe masonry components. The model was applied to simulate the experimental behaviour of sundried soil bricks and mud mortar tested in uniaxial compression and bending. Numerical simulations of the model are made mesh objective by means of a rate...article 2019
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- QuSoft, QT/e, NWO, het Lorentz Instituut, AMS-IX, StartupDelta en Microsoft, m.m.v. EZK TNO, QuTech, (author) report 2019
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- QuSoft, QT/e, NWO, het Lorentz Instituut, AMS-IX, StartupDelta en Microsoft, m.m.v. EZK TNO, QuTech, (author) report 2019
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hung Van, Pham (author), van Geer, F.C. (author), bui Tran, V. (author), Dubelaar, W. (author), oude Essink, G.H.P. (author)Study region: Mekong Delta, Vietnam (MKD). Study focus: Present-day distribution of fresh-saline groundwater is highly heterogeneous in the MKD. Close to the coastline, fresh groundwater is found in aquifers up to 500 m below ground surface. To gain better insight into the fresh-saline groundwater evolution since the late Pleistocene, we...article 2019
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Kuiper, S. (author), Doelman, N.J. (author), Human, J.D. (author), Saathof, R. (author), Klop, W.A. (author), Maniscalco, M.P. (author)TNO is developing Deformable Mirror (DM) technology, targeted for aberration correction in high-end Adaptive Optics (AO) applications in the field of lithography, astronomy, space and laser communication. The heart of this deformable mirror technology is a unique actuator technology based on the variable reluctance principle. The main advantages...conference paper 2018
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Verweij, J.M. (author), Nelskamp, S.N. (author), ten Veen, J.H. (author), de Bruin, G. (author), Geel, K. (author), Donders, T.H. (author)Understanding the shallow gas system is critical for assessing its potential as an energy source, for evaluating the possible hazard of shallow gas for drilling and wind farm locations and for evaluating the effect of gas emissions at the seabed on marine ecosystems and climate. This paper presents the key elements and processes of the microbial...article 2018
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- li Piani, T. (author), Weerheijm, J. (author), Koene, L. (author), Sluys, L.J. (author) conference paper 2018
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Pierik, H.J. (author), Stouthamer, E. (author), Cohen, K.M. (author)This paper presents reconstructions on natural levee development in the Rhine-Meuse delta, the Netherlands, during the first millennium CE, covering the full delta plain. It is the first study that performs this on a delta scale, which allows seeing the delta-wide trends on levee-forming controls and their feedbacks. We mapped the levee...article 2017
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- Garripoli, C. (author), van der Steen, J.L.P.J. (author), Smits, E. (author), Gelinck, G.H. (author), van Roermund, A.H.M. (author), Cantatore, E. (author) conference paper 2017
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van Asselen, S. (author), Cohen, K.M. (author), Stouthamer, E. (author)By redistributing water and sediment in delta plains, avulsions of river branches have major environmental impacts, notably in changing hydrological and peat-forming conditions in floodbasins. The central part of the Rhine-Meuse delta, with its extensive databases including detailed lithological data and high-resolution age control, offers a...article 2017
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Peeters, J. (author), Busschers, F.S. (author), Stouthamer, E. (author), Bosch, J.H.A. (author), van den Berg, M.W. (author), Wallinga, J. (author), Versendaal, A.J. (author), Bunnik, F.P.M. (author), Middelkoop, H. (author)This paper describes the sedimentary architecture, chronostratigraphy and palaeogeography of the late Middle and Late Pleistocene (Marine Isotope Stage/MIS 6-2) incised Rhine-valley fill in the central Netherlands based on six geological transects, luminescence dating, biostratigraphical data and a 3D geological model. The incised-valley fill...article 2016
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Koster, K. (author), Erkens, G. (author), Zwanenburg, C. (author)Land subsidence threatens many coastal areas. Quantifying current and predicting future subsidence are essential to sustain the viability of these areas with respect to rising sea levels. Despite its scale and severity, methods to quantify subsidence are scarce. In peat-rich subsidence hot spots, subsidence is often caused by peat compression....article 2016
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Peeters, J. (author), Busschers, F.S. (author), Stouthamer, E. (author)This paper presents the current state of knowledge on the evolution and depositional history of the River Rhine in the southern part of the North Sea basin during the upper Middle and Late Pleistocene, and its response to climate change, sea-level oscillation and glacio-isostasy. The study focuses on the development of the Eemian interglacial...article 2015
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Stafleu, J. (author), Busschers, F.S. (author)TNO Geological Survey of the Netherlands systematically produces 3D voxel models for answering subsurface related questions. The unique combination of vast amounts of borehole data and the voxelbased approach makes the models valuable new sources for exploring the Quaternary fluvial record. The latest generation of 3D voxel models (GeoTOP)...conference paper 2014
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Keshishzadeh, S. (author), Mooij, A.J. (author), Reza Mousavi, M. (author)In the context of Domain Specific Languages (DSLs), we study ways to detect faults early in the software development cycle. We propose techniques that validate a wide range of properties, classified into basic and advanced. Basic validation includes syntax checking, reference checking and type checking. Advanced validation concerns domain...conference paper 2013
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Bos, I.J. (author), Busschers, F.S. (author), Hoek, W.Z. (author)Peat and gyttja (organic lake sediment) are important indicators for past environmental conditions; they form in areas where the supply of clastic sediment is insufficient to fill the accommodation space. Previous studies of delta sediments, however, have focused mainly on clastic deposits, whereas organics have received only minimal attention....article 2012
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Bos, I.J. (author), Stouthamer, E. (author)The quantitative significance of coarse-grained deposits in the overbank realm, such as crevasse-splay deposits, has not been studied at the delta scale or at the Holocene timescale. Such knowledge would be beneficial for understanding and explaining sediment distribution in delta plains. This study addresses delta-scale distribution of sand...article 2011
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de Louw, P.G.B. (author), Eeman, S. (author), Siemon, B. (author), Voortman, B.R. (author), Gunnink, J. (author), van Baaren, E.S. (author), Oude Essink, G.H.P. (author)In deltaic areas with saline seepage, fresh water availability is often limited to shallow rainwater lenses lying on top of saline groundwater. Here we describe the characteristics and spatial variability of such lenses in areas with saline seepage and the mechanisms that control their occurrence and size. Our findings are based on different...article 2011
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