Searched for: subject:"controlled%5C%2Bstudy"
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Minguillón, M.C. (author), Cirach, M. (author), Hoek, G. (author), Brunekreef, B. (author), Tsai, M. (author), de Hoogh, K. (author), Jedynska, A. (author), Kooter, I.M. (author), Nieuwenhuijsen, M. (author), Querol, X. (author)
Trace and major elements concentrations in PM10 and PM2.5 were measured at 20 sites spread in the Barcelona metropolitan area (1 rural background, 6 urban background, 13 road traffic sites) and at 1 reference site. Three 2-week samples per site and size fraction were collected during 2009 using low volume samplers, adding a total of 120 samples....
article 2014
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Prins, R.G. (author), Pierik, F. (author), Etman, A. (author), Sterkenburg, R.P. (author), Kamphuis, C.B.M. (author), van Lenthe, F.J. (author)
In choosing appropriate buffer sizes to study environmental influences on physical activity, studies are hampered by insufficient insight into the distance elderly travel actively. This study aims at getting insight into the number of trips walked and cycled within various buffer sizes using GPS measures. Data were obtained from the Elderly And...
article 2014
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Risto, M. (author), Martens, M.H. (author)
With specific headway instructions drivers are not able to attain the exact headways as instructed. In this study, the effects of discrete headway feedback (and the direction of headway adjustment) on headway accuracy for drivers carrying out time headway instructions were assessed experimentally. Two groups of each 10 participants (one...
article 2014
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Geraedts, A.S. (author), Kleiboer, A.M. (author), Wiezer, N.M. (author), van Mechelen, W. (author), Cuijpers, P. (author)
Background: Depressive disorders are highly prevalent in the working population and are associated with excessive costs for both society and companies. Effective treatment for employees with depressive symptoms in occupational health care is limited. The purpose of this study is to investigate the effectiveness and cost-effectiveness of an...
article 2013
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Dambacher, W.M. (author), de Kort, E.H.M. (author), Blom, W.M. (author), Houben, G.F. (author), de Vries, E. (author)
Background: Children with cow's milk allergy (CMA) need a cow's milk protein (CMP) free diet to prevent allergic reactions. For this, reliable allergy-information on the label of food products is essential to avoid products containing the allergen. On the other hand, both overzealous labeling and misdiagnosis that result in unnecessary...
article 2013
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Mutlu, E. (author), Warren, S.H. (author), Matthews, P.P. (author), King, C. (author), Linak, W.P. (author), Kooter, I.M. (author), Schmid, J.E. (author), Ross, J.A. (author), Ian Gilmour, M. (author), DeMarini, D.M. (author)
Several types of diesel exhaust particles (DEPs) have been used for toxicology studies, including a highorganic automobile DEP (A-DEP) from Japan, and a low-organic forklift DEP developed by the National Institute of Standards and Technology (N-DEP). However, these DEPs were not characterized extensively for chemical composition or sub...
article 2013
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Wagenaar, A.F. (author), Kompier, M.A.J. (author), Houtman, I.L.D. (author), van den Bossche, S.N.J. (author), Taris, T.W. (author)
OBJECTIVE:: The healthy worker effect implies that healthy workers go "up" in employment status whereas less healthy workers go "down" into precarious temporary employment or unemployment. These hypotheses were tested during an economic recession, by predicting various upward and downward contract trajectories, based on workers' health status,...
article 2012
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Wopereis, S. (author), Radonjic, M. (author), Rubingh, C. (author), van Erk, M. (author), Smilde, A. (author), van Duyvenvoorde, W. (author), Cnubben, N. (author), Kooistra, T. (author), van Ommen, B. (author), Kleemann, R. (author)
The prevalence of diabetes mellitus Type 2 could be significantly reduced by early identification of subjects at risk, allowing for better prevention and earlier treatment. Glucose intolerance (GI) is a hallmark of the prediabetic stage. This study aims at identifying 1) prognostic biomarkers predicting the risk of developing GI later in life...
article 2012
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Jacobs, J.H. (author), Fuertes, E. (author), Krop, E.J.M. (author), Spithoven, J. (author), Tromp, P. (author), Heederik, D.J.J. (author)
Objectives: To describe associations among swimming, respiratory health, allergen sensitisation and Clara cell protein 16 (CC16) levels in Dutch schoolchildren. Trichloramine levels in swimming pool air were determined to assess potential exposure levels. Methods: Respiratory health and pool attendance information was collected from 2359...
article 2012
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Mariman, R. (author), Kremer, S.H.A. (author), van Erk, M. (author), Lagerweij, T. (author), Koning, F. (author), Nagelkerken, L. (author)
Background: Host-microbiota interactions in the intestinal mucosa play a major role in intestinal immune homeostasis and control the threshold of local inflammation. The aim of this study was to evaluate the efficacy of probiotics in the recurrent trinitrobenzene sulfonic acid (TNBS)-induced colitis model and gain more insight into protective...
article 2012
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Reus, A.A. (author), Usta, M. (author), Kenny, J.D. (author), Clements, P.J. (author), Pruimboom-Brees, I. (author), Aylott, M. (author), Lynch, A.M. (author), Krul, C.A.M. (author)
An in vivo photomicronucleus test (MNT) using rat skin, the target organ for photoirritancy and carcinogenicity, was recently described. The assay was evaluated using fluoroquinolone (FQ) antibiotics with varying degrees of phototoxic potency (i.e. sparflocacin [SPFX], lomefloxacin [LOFX], ciprofloxacin [CIFX], levofloxacin [LEFX], gemifloxacin ...
article 2012
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de Korte, E.M. (author), Huysmans, M.A. (author), de Jong, A.M. (author), van de Ven, J.G.M. (author), Ruijsendaal, M. (author)
This study investigated the effects of non-obtrusive feedback on continuous lifted hand/finger behaviour, task performance and comfort. In an experiment with 24 participants the effects of two visual and two tactile feedback signals were compared to a no-feedback condition in a computer task. Results from the objective measures showed that all...
article 2012
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Ellegast, R.P. (author), Kraft, K. (author), Groenesteijn, L. (author), Krause, F. (author), Berger, H. (author), Vink, P. (author)
Prolonged and static sitting postures provoke physical inactivity at VDU workplaces and are therefore discussed as risk factors for the musculoskeletal system. Manufacturers have designed specific dynamic office chairs featuring structural elements which promote dynamic sitting and therefore physical activity. The aim of the present study was to...
article 2012
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Stomp-van den Berg, G.M. (author), Hendriksen, I.J.M. (author), Bruinvels, D.J. (author), Twisk, J.W.R. (author), van Mechelen, W. (author), van Poppel, M.N.M. (author)
The objective of this study was to examine which factors during pregnancy and postpartum predict pelvic girdle pain (PGP) at 12 weeks postpartum among working women. A total of 548 Dutch pregnant employees were recruited in 15 companies, mainly health care, child care, and supermarkets. The definition of PGP was any pain felt in the pelvic...
article 2012
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Vos, P.A.J.M. (author), Degroot, J. (author), Barten-Van Rijbroek, A.D. (author), Zuurmond, A.-M. (author), Bijlsma, J.W.J. (author), Mastbergen, S.C. (author), Lafeber, F.P.J.G. (author)
Osteoarthritis is a highly prevalent disease, age being the main risk factor. The age-related accumulation of advanced-glycation-endproducts (AGEs) adversely affects the mechanical and biochemical properties of cartilage. The hypothesis that accumulation of cartilage AGEs in combination with surgically induced damage predisposes to the...
article 2012
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Janssens, A.C.J.W. (author), Henneman, L. (author), Detmar, S.B. (author), Khoury, M.J. (author), Steyerberg, E.W. (author), Eijkemans, M.J.C. (author), Mushkudiani, N. (author), Oostra, B.A. (author), van Duijn, C.M. (author), MacKenbach, J.P. (author)
Objective: We investigated the accuracy of self-reported family history for diabetes, hypertension, and overweight against two reference standards: family history based on physician-assessed health status of relatives and on self-reported personal health status of relatives. Study Design and Setting: Subjects were participants from the Erasmus...
article 2012
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Stein, N.E. (author), Hamelers, H.V.M. (author), van Straten, G. (author), Keesman, K.J. (author)
Polarization curves are of paramount importance for the detection of toxic components in microbial fuel cell (MFC) based biosensors. In this study, polarization curves were made under non-toxic conditions and under toxic conditions after the addition of various concentrations of nickel, bentazon, sodiumdodecyl sulfate and potassium ferricyanide....
article 2012
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Engelen, V. (author), Detmar, S. (author), Koopman, H. (author), Maurice-Stam, H. (author), Caron, H. (author), Hoogerbrugge, P. (author), Egeler, R.M. (author), Kaspers, G. (author), Grootenhuis, M. (author)
Background: The aim of the current study is to investigate the effectiveness of an intervention that provides health-related quality of life (HRQOL) scores of the patient (the QLIC-ON PROfile) to the pediatric oncologist. Procedure: Children with cancer participated in a sequential cohort intervention study: intervention N=94, control N=99....
article 2012
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Liebrechts-Akkerman, G. (author), Lao, O. (author), Liu, F. (author), van Sleuwen, B.E. (author), Engelberts, A.C. (author), L'Hoir, M.P. (author), Tiemeier, H.W. (author), Kayser, M. (author)
Background: Sudden infant death syndrome (SIDS) is the unexpected death of an infant that remains unexplained after a thorough investigation of the circumstances, family history, paediatric investigation and complete autopsy. In Western society, it is the leading cause of post-neonatal death below 1 year of age. In the Netherlands, the SIDS...
article 2011
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Lu, Y. (author), Boekschoten, M.V. (author), Wopereis, S. (author), Müller, M. (author), Kersten, S. (author)
Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice. Physiol Genomics 43: 1307-1318, 2011. First published September 27, 2011; doi:10.1152/physiolgenomics.00100.2011. Elevated circulating triglycerides, which are considered a risk factor for cardiovascular disease, can be targeted by treatment with...
article 2011
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