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- Veeningen, M. (author), Chatterjea, S. (author), Horváth, A.Z. (author), Spindler, G. (author), Boersma, E. (author), van der Spek, P. (author), van der GaliËn, O. (author), Gutteling, J. (author), Kraaij, W. (author), Veugen, P.J.M. (author) conference paper 2018
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Ashton, R. (author), de Wever, B. (author), Fuchs, H.W. (author), Gaca, M. (author), Hill, E. (author), Krul, C.A.M. (author), Poth, A. (author), Roggen, E.L. (author)Despite changing attitudes towards animal testing and current legislation to protect experimental animals, the rate of animal experiments seems to have changed little in recent years. On May 15–16, 2013, the In Vitro Testing Industrial Platform (IVTIP) held an open meeting to discuss the state of the art in alternative methods, how companies...article 2014
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Selimis, G. (author), Huang, L. (author), Massé, F. (author), Tsekoura, I. (author), Ashouei, M. (author), Catthoor, F. (author), Huisken, J. (author), Stuyt, J. (author), Dolmans, G. (author), Penders, J. (author), de Groot, H. (author)In order for wireless body area networks to meet widespread adoption, a number of security implications must be explored to promote and maintain fundamental medical ethical principles and social expectations. As a result, integration of security functionality to sensor nodes is required. Integrating security functionality to a wireless sensor...article 2011
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TNO Kwaliteit van Leven (author), Matthys, C. (author), Bucchini, L. (author), Busstra, M.C. (author), Cavelaars, A.E.J.M. (author), Eleftheriou, P. (author), Garc?a-Alvarez, A. (author), Fairweather-Tait, S. (author), Gurinovi?, M. (author), van Ommen, B. (author), Contor, L. (author)Approaches through which reference values for micronutrients are derived, as well as the reference values themselves, vary considerably across countries. Harmonisation is needed to improve nutrition policy and public health strategies. The EURRECA (EURopean micronutrient RECommendations Aligned, http://www.eurreca.org) Network of Excellence is...article 2010
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Simons, M. (author), Valk, P.J.L. (author)This primary objective of this paper is to discuss the usefulness of melatonin for reducing symptoms of circadian rhythm disturbances in aircrew. Literature and own data of circadian disruptions and symptoms of aircrew were analysed. Considerations concerning the use of melatonin by aircrew are discussed. The main outcomes were as follows....article 2009
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Mert, A. (author), Klöpping-Ketelaars, I. (author), Bles, W. (author), TNO Defensie en Veiligheid (author)Motion sickness incidence (MSI) for vertical sinusoidal motion reaches a maximum at 0.167 Hz. Normal breathing frequency is close to this frequency. There is some evidence for synchronization of breathing with this stimulus frequency. If this enforced breathing takes place over a larger frequency range (0.05-0.8 Hz) and whether this contributes...article 2009
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van der Laan, J.W. (author), Forster, R. (author), Ledwith, B. (author), Gruber, M. (author), Gould, S. (author), Segal, L. (author), Penninks, A. (author), TNO Kwaliteit van Leven (author)Vaccine research and development is a heterogeneous and intensely active area, encompassing the development of many different kinds of novel preventive and therapeutic vaccines (eg, against infectious, allergic, and autoimmune diseases, cancer, etc). Included in this is the development of different types of vaccines (eg, DNA vaccines, novel...article 2009
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- Bottini, A.A. (author), Alepee, N. (author), Phillips, B. (author), Gribaldo, L. (author), de Silva, O. (author), Hartung, T. (author), Hendriksen, C. (author), Kuil, J. (author), Pazos, P. (author), Rhein, C. (author), Schiffelers, M.-J. (author), Stokes, W. (author), Theobald, A. (author), Vidal, J.-M. (author), van de Sandt, H. (author), Breier, S. (author), Sintes, J.R. (author), Blaauboer, B. (author), TNO Kwaliteit van Leven (author) article 2008
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TNO Kwaliteit van Leven (author), Gerritsen, G. (author), van der Hoogt, C.C. (author), Schaap, F.G. (author), Voshol, P.J. (author), Kypreos, K.E. (author), Maeda, N. (author), Groen, A.K. (author), Havekes, L.M. (author), Rensen, P.C.N. (author), van Dijk, K.W. (author)Apolipoprotein E2 (apoE2)-associated hyperlipidemia is characterized by a disturbed clearance of apoE2-enriched VLDL remnants. Because excess apoE2 inhibits LPL-mediated triglyceride (TG) hydrolysis in vitro, we in vestigated whether direct or indirect stimulation of LPL activity in vivo reduces the apoE2-associated hypertriglyc-eridemia. Here,...article 2008
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- TNO Kwaliteit van Leven (author), Mateo Anson, N. (author), Berg, R.V.D. (author), Havenaar, R. (author), Haenen, G. (author), Bast, A. (author) article 2008
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Terpstra, F.G. (author), Rechtman, D.J. (author), Lee, M.L. (author), van Hoeij, K. (author), Berg, H. (author), van Engelenberg, F.A.C. (author), van 't Wout, A.B. (author), TNO Kwaliteit van Leven (author)In the United States, concerns over the transmission of infectious diseases have led to donor human milk generally being subjected to pasteurization prior to distribution and use. The standard method used by North American milk banks is Holder pasteurization (63°C for 30 minutes). The authors undertook an experiment to validate the effects of a...article 2007
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Hulskotte, J.H.J. (author), van der Gon, H.A.C.D. (author), Visschedijk, A.J.H. (author), Schaap, M. (author), TNO Bouw en Ondergrond (author)In this article we show that brake wear from road traffic vehicles is an important source of atmospheric (participate) copper concentrations in Europe. Consequently, brake wear also contributes significantly to deposition fluxes of copper to surface waters. We estimated the copper emission due to brake wear to be 2.4 kiloton per year. For...conference paper 2007
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- Kimber, I. (author), Agius, R. (author), Basketter, D.A. (author), Corsini, E. (author), Cullinan, P. (author), Dearman, R.J. (author), Gimenez-Arnau, E. (author), Greenwell, L. (author), Hartung, T. (author), Kuper, F. (author), Maestrelli, P. (author), Roggen, E. (author), Rovida, C. (author), Casati, S. (author), TNO Kwaliteit van Leven (author) article 2007
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- Basketter, D. (author), Pease, C. (author), Kasting, G. (author), Kimber, I. (author), Casati, S. (author), Cronin, M. (author), Diembeck, W. (author), Gerberick, F. (author), Hadgraft, J. (author), Hartung, T. (author), Marty, J.P. (author), Nikolaidis, E. (author), Patlewicz, G. (author), Roberts, D. (author), Roggen, E. (author), Rovida, C. (author), van de Sandt, J. (author), TNO Kwaliteit van Leven (author) article 2007
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Buijs, P.C. (author), van Dijk, F.J.H. (author), Evers, M. (author), van de Klink, J.J.L. (author), Anema, H. (author), TNO Kwaliteit van Leven (author)Increasingly, workers have psychological work-related complaints, endangering their work ability and causing considerable economic losses. Many employees consult their general practitioner (GP). He, however, often pays insufficient attention to work-relatedness or to coordination with occupational physicians (OPs). Appropriate guidelines are...article 2007
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Poucke, C.V. (author), Dumoulin, F. (author), Yakkundi, S. (author), Situ, C. (author), Elliott, C.T. (author), Grutters, E.M. (author), Verheijen, R. (author), Schilt, R. (author), Eriksson, S. (author), Peteghem, C.V. (author), TNO Kwaliteit van Leven (author)A chemical confirmation method for the identification and quantification of five banned antibacterial growth promoters (AGPs) in animal feed was developed and in-house validated as part of the European Feedstuffs-RADIUS project [1]. To complete the validation process a collaborative trial was performed by eleven laboratories within the European...article 2006
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Gao, K. (author), Xu, A. (author), Krul, C.A.M. (author), Venema, K. (author), Liu, Y. (author), Niu, Y. (author), Lu, J. (author), Bensoussan, L. (author), Seeram, N.P. (author), Heber, D. (author), Henning, S.M. (author), TNO Kwaliteit van Leven (author)Dietary flavonoids are poorly absorbed from the gastrointestinal tract. Colonic bacteria convert flavonoids into smaller phenolic acids (PA), which can be absorbed into the circulation and may contribute to the chemopreventive activity of the parent compounds. The purpose of our study was to determine whether flavonoids from green and black tea ...article 2006
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Zvinavashe, E. (author), Murk, A.J. (author), Vervoort, J. (author), Soffers, A.E.M.F. (author), Freidig, A. (author), Rietjens, I.M.C.M. (author), TNO Kwaliteit van Leven (author)Fifteen experimental literature data sets on the acute toxicity of substituted nitrobenzenes to algae (Scenedesmus obliquus, Chlorella pyrenoidosa, C. vulgaris), daphnids (Daphnia magna, D. carinata), fish (Cyprinus carpio, Poecilia reticulata), protozoa (Tetrahymena pyriformis), bacteria (Phosphobacterium phosphoreum), and yeast (Saccharomyces...article 2006
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Kuper, C.F. (author), TNO Kwaliteit van Leven (author)Mucosa-associated lymphoid tissue (MALT) is a generalized term incorporating a disseminated collection of lymphoid tissues in multiple sites throughout the body. MALT sites that have been/are primarily studied include bronchus-associated lymphoid tissue (BALT), gut-associated lymphoid tissue (GALT), and nasopharynx-associated lymphoid tissue ...article 2006
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van Mispelaar, V.G. (author), Janssen, H.G. (author), Tas, A.C. (author), Schoenmakers, P.J. (author), TNO Kwaliteit van Leven (author)For practical chromatographers it is extremely difficult to judge the merits and limitations of new technological developments. On the other hand, it is nearly impossible for those at the forefront of technology to judge the implications of their efforts for all specific applications of chromatography. Both chromatographers and researchers can...article 2005