Searched for: subject:"computer%5C+model"
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de Braaf, B. (author), Rops, C.M. (author), Storm, C. (author)
In atomic layer deposition (ALD), thin layers of materials are deposited on a substrate with atomic layer precision in the vertical direction. The ability to control layer growth in the lateral direction as well is expected to greatly increase the potential of ALD as a path to the bottom-up additive fabrication of electronic devices like solar...
article 2021
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Iniguez, B. (author), Nathan, A. (author), Kloes, A. (author), Bonnassieux, Y. (author), Romanjek, K. (author), Charbonneau, M. (author), van der Steen, J.L. (author), Gelinck, G.H. (author), Gneiting, T. (author), Mohamed, F. (author), Ghibaudo, G. (author), Cerdeira, A. (author)
We review recent compact modeling solutions for Organic and Amorphous Oxide TFTs (OTFTs and AOS TFTs, respectively), which were developed, under the framework of the EU-funded project DOMINO, to address issues specifically connected to the physics of these devices. In particular, using different approaches, analytical equations were formulated...
article 2021
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Moné, M.J. (author), Pallocca, G. (author), Escher, S.E. (author), Exner, T. (author), Herzler, M. (author), Hougaard Bennekou, S. (author), Kamp, H. (author), Kroese, E.D. (author), Leist, M. (author), Steger-Hartmann, T. (author), van de Water, B. (author)
In 2016, the European Commission launched the EU-ToxRisk research project to develop and promote animal-free approaches in toxicology. The 36 partners of this consortium used in vitro and in silico methods in the context of case studies (CSs). These CSs included both compounds with a highly defined target (e.g. mitochondrial respiratory chain...
article 2020
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Westerhout, J. (author), Krone, T. (author), Snippe, A. (author), Babé, L. (author), McClain, S.U. (author), Ladics, G.S. (author), Houben, G.G. (author), Verhoeckx, K.C. (author)
Alternative and sustainable protein sources (e.g., algae, duckweed, insects) are required to produce (future) foods. However, introduction of new food sources to the market requires a thorough risk assessment of nutritional, microbial and toxicological risks and potential allergic responses. Yet, the risk assessment of allergenic potential of...
article 2019
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de Greeff, J. (author), Hayes, B. (author), Gombolay, M. (author), Johnson, M. (author), Neerincx, M.A. (author), van Diggelen, J. (author), Cefkin, M. (author), Kruijff-Korbayová, I. (author)
As robots that share working and living environments with humans proliferate, human-robot teamwork (HRT) is becoming more relevant every day. By necessity, these HRT dynamics develop over time, as HRT can hardly happen only in the moment. What theories, algorithms, tools, computational models and design methodologies enable effective and safe...
conference paper 2018
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Remington, B. (author), Broekman, H.C.H. (author), Blom, W.M. (author), Capt, A. (author), Crevel, R.W.R. (author), Dimitrov, I. (author), Faeste, C.K. (author), Fernandez-Canton, R. (author), Giavi, S. (author), Houben, G.F. (author), Glenn, K.C. (author), Madsen, C.B. (author), Kruizinga, A.K. (author), Constable, A. (author)
The development and introduction of new dietary protein sources has the potential to improve food supply sustainability. Understanding the potential allergenicity of these new or modified proteins is crucial to ensure protection of public health. Exposure to new proteins may result in de novo sensitization, with or without clinical allergy, or...
article 2018
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de Juncker, M.A.M. (author), Huizing, D. (author), del Vecchyo, M.R.O. (author), Phillipson, F. (author), Sangers, A. (author)
Problem statements and solution methods in mathematical synchromodal transportation problems depend greatly on a set of model choices for which no rule of thumb exists. In this paper, a framework is introduced with which the model choices in synchromodal transportation problems can be classified, based on literature. This framework should help...
conference paper 2017
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Frank Phillipson, F. (author), Ortega del Vecchyo, M. (author), van Ginkel, B. (author), Huizing, S. (author), Sangers, A. (author)
In logistic delivery chains time windows are common. An arrival has to be in a certain time interval, at the expense of waiting time or penalties if the time limits are exceeded. This paper looks at the optimal placement of those time intervals in a specific case of a barge visiting two ports in sequence. For the second port a possible delay or...
conference paper 2017
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de Huncker, M.A.M. (author), Huizing, D. (author), Ortega del Vecchyo, M.R. (author), Phillipson, F. (author), Sangers, A. (author)
Problem statements and solution methods in mathematical synchromodal transportation problems depend greatly on a set of model choices for which no rule of thumb exists. In this paper, a framework is introduced with which the model choices in synchromodal transportation problems can be classified, based on literature. This framework help...
conference paper 2017
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van de Steeg, E. (author), Venhorst, J. (author), Jansen, H.T. (author), Nooijen, I.H.G. (author), Degroot, J. (author), Wortelboer, H.M. (author), Vlaming, M.L.H. (author)
Human organic anion-transporting polypeptide 1B1 (OATP1B1) and OATP1B3 are important hepatic uptake transporters. Early assessment of OATP1B1/1B3-mediated drug-drug interactions (DDIs) is therefore important for successful drug development. A promising approach for early screening and prediction of DDIs is computational modeling. In this study...
article 2015
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Smit, S.K. (author)
Misschien wel de beste oplossing tegen overlast in woonwijken: een computermodel om overlastsituaties te voorspellen. Selmar Smit van TNO ziet reële kansen voor zo’n model. Daarmee kan een wijk overlastbestendig worden ontworpen. Bijvoorbeeld door een buurthuis te bouwen, of een park aanleggen.
article 2014
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Azzopardi, G. (author), Petkov, N. (author)
The primate visual system has an impressive ability to generalize and to discriminate between numerous objects and it is robust to many geometrical transformations as well as lighting conditions. The study of the visual system has been an active reasearch field in neuropysiology for more than half a century. The construction of computational...
bookPart 2014
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Reimer, R.A. (author), Maathuis, A.J.H. (author), Venema, K. (author), Lyon, M.R. (author), Gahler, R.J. (author), Wood, S. (author)
Many of the health benefits associated with dietary fiber are attributed to their fermentation by microbiota and production of short chain fatty acids (SCFA). The aim of this study was to investigate the fermentability of the functional fiber PolyGlyopleX® (PGX®) in vitro. A validated dynamic, computer-controlled in vitro system simulating the...
article 2014
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Azzopardi, G. (author)
doctoral thesis 2013
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Erkin, Z. (author), Veugen, T. (author), Toft, T. (author), Lagendijk, R.L. (author)
Clustering is a very important tool in data mining and is widely used in on-line services for medical, financial and social environments. The main goal in clustering is to create sets of similar objects in a data set. The data set to be used for clustering can be owned by a single entity, or in some cases, information from different databases is...
article 2013
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Veugen, P.J.M. (author)
When processing signals in the encrypted domain, homomorphic encryption can be used to enable linear operations on encrypted data. Comparison of encrypted data however requires an additional protocol between the parties and will be relatively expensive. A well-known and frequently used comparison protocol is by Damgard, Geisler and Kroigaard. We...
conference paper 2012
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Kotlarski, J.D. (author), Moet, D.J.D. (author), Blom, P.W.M. (author)
Lowering of the optical band gap of conjugated polymers in bulk heterojunction solar cells not only leads to an increased absorption but also to an increase of the optimal active layer thickness due to interference effects at longer wavelengths. The increased carrier densities due to the enhanced absorption and thicker active layers make low...
article 2011
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Meekes, J.A.C. (author), Zhang, X. (author), Abdul Fattah, R. (author)
Geophysical monitoring of the dynamical behavior of subsurface reservoirs (oil, gas, CO2) remains an important issue in geophysical research. A new idea for reservoir monitoring based on electrical resistivity tomography was developed at TNO. The essential element of the so-called BSEMT (Borehole to Surface Electrical Monitoring Technique)...
conference paper 2011
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de Graaf, A.A. (author), van Schalkwijk, D.B. (author)
At present, several measurement technologies are available for generating highly detailed concentration-size profiles of lipoproteins, offering increased diagnostic potential. Computational models are useful in aiding the interpretation of these complex datasets and making the data more accessible for clinical diagnosis. They do so by...
article 2011
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van Schalkwijk, D.B. (author), van Bochove, K. (author), van Ommen, B. (author), Freidig, A.P. (author), van Someren, E.P. (author), van der Greef, J. (author), de Graaf, A.A. (author), TNO Kwaliteit van Leven (author)
This article provides methodological and technical considerations to researchers starting to develop computational model-based diagnostics using clinical chemistry data.These models are of increasing importance, since novel metabolomics and proteomics measuring technologies are able to produce large amounts of data that are difficult to...
article 2010
Searched for: subject:"computer%5C+model"
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