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Physical capacity in relation to low back, neck, or shoulder pain in a working population

van Hamberg - Reenen, H.H. (author), Ariëns, G.A.M. (author), Blatter, B.M. (author), Twisk, J.W.R. (author), van Mechelen, W. (author), Bongers, P.M. (author), TNO Kwaliteit van Leven (author)

Aims: To investigate the longitudinal relation between physical capacity (isokinetic lifting strength, static endurance of the back, neck, and shoulder muscles, and mobility of the spine) and low back, neck, and shoulder pain. Methods: In this prospective cohort study, 1789 Dutch workers participated. At baseline, isokinetic lifting strength,...

article 2006

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Nitrate intake does not influence bladder cancer risk: The Netherlands Cohort Study

Zeegers, M.P. (author), Selen, R.F.M. (author), Kleinjans, J.C.S. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)

Objectives: N-nitroso compounds, endogenously formed from nitrate-derived nitrite, are suspected to be important bladder carcinogens. However, the association between nitrate exposure from food or drinking water and bladder cancer has not been substantially investigated in epidemiologic studies. Methods: We evaluated the associations between...

article 2006

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Job stress and major coronary events: Results from the Job Stress, Absenteeism and Coronary Heart Disease in Europe study

Kornitzer, M. (author), DeSmet, P. (author), Sans, S. (author), Dramaix, M. (author), Boulenguez, C. (author), DeBacker, G. (author), Ferrario, M. (author), Houtman, I. (author), Isacsson, S.O. (author), Ostergren, P.O. (author), Peres, I. (author), Pelfrene, E. (author), Romon, M. (author), Rosengren, A. (author), Cesana, G. (author), Wilhelmsen, L. (author), TNO Kwaliteit van Leven (author)

AIMS: The intention of this study is to investigate the relationship of the demands/control/strain model with hard coronary events in an epidemiological, prospective, multicenter, European study. METHODS AND RESULTS: Six cohorts (Brussels, Ghent, Lille, Barcelona, Göteborg and Malmö) from four European countries (Belgium, France, Spain and...

article 2006

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Risk estimation for carcinogens based on epidemiological data: A structured approach, illustrated by an example on chromium

Goldbohm, R.A. (author), Tielemans, E.L.J.P. (author), Heederik, D. (author), Rubingh, C.M. (author), Dekkers, S. (author), Willems, M.I. (author), Dinant Kroese, E. (author), TNO Kwaliteit van Leven (author)

It is generally recognized that human, epidemiological data, if available, are preferred as the starting point for quantitative risk analysis above the use of data from animal studies. Although methods to obtain proper risk estimates from epidemiological data are available, several impediments prevent their widespread application. These...

article 2006

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Methods for pooling results of epidemiologic studies: The pooling project of prospective studies of diet and cancer

Smith-Warner, S.A. (author), Spiegelman, D. (author), Ritz, J. (author), Albanes, D. (author), Beeson, W.L. (author), Bernstein, L. (author), Berrino, F. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Cho, E. (author), Colditz, G.A. (author), Folsom, A.R. (author), Freudenheim, J.L. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Graham, S. (author), Harnack, L. (author), Horn-Ross, P.L. (author), Krogh, V. (author), Leitzmann, M.F. (author), McCullough, M.L. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Schatzkin, A. (author), Shore, R. (author), Virtanen, M. (author), Willett, W.C. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Zhang, S.M. (author), Hunter, D.J. (author), TNO Kwaliteit van Leven (author)

With the growing number of epidemiologic publications on the relation between dietary factors and cancer risk, pooled analyses that summarize results from multiple studies are becoming more common. Here, the authors describe the methods being used to summarize data on diet-cancer associations within the ongoing Pooling Project of Prospective...

article 2006

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Intake of the major carotenoids and the risk of epithelial ovarian cancer in a pooled analysis of 10 cohort studies

Koushik, A. (author), Hunter, D.J. (author), Spiegelman, D. (author), Anderson, K.E. (author), Buring, J.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Hankinson, S.E. (author), Larsson, S.C. (author), Leitzmann, M. (author), Marshall, J.R. (author), McCullough, M.L. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Ross, J.A. (author), Schatzkin, A. (author), Schouten, L.J. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)

Carotenoids, found in fruits and vegetables, have the potential to protect against cancer because of their properties, including their functions as precursors to vitamin A and as antioxidants. We examined the associations between intakes of α-carotene, β-carotene, β-cryptoxanthin, lutein/zeaxanthin and lycopene and the risk of invasive...

article 2006

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A pooled analysis of 12 cohort studies of dietary fat, cholesterol and egg intake and ovarian cancer

Genkinger, J.M. (author), Hunter, D.J. (author), Spiegelman, D. (author), Anderson, K.E. (author), Beeson, W.L. (author), Buring, J.E. (author), Colditz, G.A. (author), Fraser, G.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Hankinson, S.E. (author), Koenig, K.L. (author), Larsson, S.C. (author), Leitzmann, M. (author), McCullough, M.L. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Ross, J.A. (author), Schatzkin, A. (author), Schouten, L.J. (author), Smit, E. (author), Willett, W.C. (author), Wolk, A. (author), Zeleniuch-Jacquotte, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven TNO Voeding (author)

Fat and cholesterol are theorized to promote ovarian carcinogenesis by increasing circulating estrogen levels. Although case-control studies have reported positive associations between total and saturated fat intake and ovarian cancer risk, two cohort studies have observed null associations. Dietary cholesterol and eggs have been positively...

article 2006

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Dairy products and ovarian cancer: A pooled analysis of 12 cohort studies

Genkinger, J.M. (author), Hunter, D.J. (author), Spiegelman, D. (author), Anderson, K.E. (author), Arslan, A. (author), Beeson, W.L. (author), Buring, J.E. (author), Fraser, G.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Hankinson, S.E. (author), Jacobs Jr., D.R. (author), Koushik, A. (author), Lacey Jr., J.V. (author), Larsson, S.C. (author), Leitzmann, M. (author), McCullough, M.L. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Scheuten, L.J. (author), Shore, R. (author), Smit, E. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)

Background: Dairy foods and their constituents (lactose and calcium) have been hypothesized to promote ovarian carcinogenesis. Although case-control studies have reported conflicting results for dairy foods and lactose, several cohort studies have shown positive associations between skim milk, lactose, and ovarian cancer. Methods: A pooled...

article 2006

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Predicting older adults' maintenance in exercise participation using an integrated social psychological model

Stiggelbout, M. (author), Hopman-Rock, M. (author), Crone, M. (author), Lechner, L. (author), van Mechelen, W. (author), TNO Kwaliteit van Leven (author)

Little is known about the predictors of maintenance in organized exercise programmes. The aim of this study was to investigate the behavioral predictors of maintenance of exercise participation in older adults, using an integrated social psychological model. To this end, we carried out a prospective cohort study (n = 1725; age 50 years or older)...

article 2006

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Physical activity and risk of ovarian cancer: Results from the Netherlands Cohort Study (The Netherlands)

Biesma, R.G. (author), Schouten, L.J. (author), Dirx, M.J.M. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven TNO Voeding (author)

Objective: To investigate the association between nonoccupational physical activity and the risk of ovarian cancer among post-menopausal women. Methods: The Netherlands Cohort Study on Diet and Cancer consists of 62,573 women aged 55-69 years at baseline. Information regarding baseline nonoccupational physical activity and history of sports...

article 2006

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Modeling predicted that tobacco control policies targeted at lower educated will reduce the differences in life expectancy

Bemelmans, W.J.E. (author), van Lenthe, F. (author), Hoogenveen, R. (author), Kunst, A. (author), Deeg, D.J.H. (author), van den Brandt, P.A. (author), Goldbohm, R.A. (author), Verschuren, W.M.M. (author), TNO Kwaliteit van Leven (author)

Background and Objective: To estimate the effects of reducing the prevalence of smoking in lower educated groups on educational differences in life expectancy. Methods: A dynamic Markov-type multistate transition model estimated the effects on life expectancy of two scenarios. A "maximum scenario" where educational differences in prevalence of...

article 2006

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Preterm birth and later insulin resistance: Effects of birth weight and postnatal growth in a population based longitudinal study from birth into adult life

Finken, M.J.J. (author), Keijzer-Veen, M.G. (author), Dekker, F.W. (author), Frölich, M. (author), Hille, E.T.M. (author), Romijn, J.A. (author), Wit, J.M. (author), TNO Kwaliteit van Leven (author)

Aims/hypothesis: An increased risk of type 2 diabetes mellitus is associated with low birthweight after full-term gestation, including amplification of this risk by weight gain during infancy and adult body composition. Premature birth is also associated with insulin resistance, but studies conducted so far have not provided follow-up into...

article 2006

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Heme and chlorophyll intake and risk of colorectal cancer in the Netherlands cohort study

Balder, H.F. (author), de Vogel, J. (author), Jansen, M.C.J.F. (author), Weijenberg, M.P. (author), van den Brandt, P.A. (author), Westenbrink, S. (author), van der Meer, R.D. (author), Goldbohm, R.A. (author), TNO Kwaliteit van Leven (author)

Background: The evidence for red meat as a determinant of colorectal cancer remains equivocal, which might be explained by differences in heme content. Heme is the prooxidant, iron-containing porphyrin pigment of meat and its content depends on the type of meat. Chlorophyll from green vegetables might modify this association. Methods: The...

article 2006

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Meta-analysis of the relationship between alcohol consumption and coronary heart disease and mortality in type 2 diabetic patients

Koppes, L.L.J. (author), Dekker, J.M. (author), Hendriks, H.F.J. (author), Bouter, L.M. (author), Heine, R.J. (author), TNO Kwaliteit van Leven (author)

Aims/hypothesis: This systematic review examines the relationship between alcohol consumption and long-term complications of type 2 diabetes. Meta-analyses could only be performed for total mortality, mortality from CHD, and CHD incidence, because the availability of articles on other complications was too limited. Materials and methods: A...

article 2006

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Cigarette smoking, von Hippel-Lindau gene mutations and sporadic renal cell carcinoma

TNO Kwaliteit van Leven (author), van Dijk, B.A.C. (author), Schouten, L.J. (author), Oosterwijk, E. (author), Hulsbergen van de, (author), Kaa, C.A. (author), Kiemeney, L.A.L.M. (author), Goldbohm, R.A. (author), Schalken, J.A. (author), van den Brandt, P.A. (author)

We investigated whether smoking is associated with mutations in the Von Hippel-Lindau (VHL) gene in 337 cases of sporadic renal cell carcinoma (RCC) among 120 852 people followed for 11.3 years; the findings suggest that smoking causes RCC independently of VHL gene mutations. © 2006 Cancer Research. Chemicals / CAS: adenine, 22177-51-1, 2922-28...

article 2006

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Alcohol intake and ovarian cancer risk: A pooled analysis of 10 cohort studies

TNO Kwaliteit van Leven TNO Voeding (author), Genkinger, J.M. (author), Hunter, D.J. (author), Spiegelman, D. (author), Anderson, K.E. (author), Buring, J.E. (author), Freudenheim, J.L. (author), Goldbohm, R.A. (author), Harnack, L. (author), Hankinson, S.E. (author), Larsson, S.C. (author), Leitzmann, M. (author), McCullough, M.L. (author), Marshall, J. (author), Miller, A.B. (author), Rodriguez, C. (author), Rohan, T.E. (author), Schatzkin, A. (author), Schouten, L.J. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author)

Alcohol has been hypothesized to promote ovarian carcinogenesis by its potential to increase circulating levels of estrogen and other hormones; through its oxidation byproduct, acetaldehyde, which may act as a cocarcinogen; and by depletion of folate and other nutrients. Case-control and cohort studies have reported conflicting results relating...

article 2006

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Predicting the duration of sickness absence for patients with common mental disorders in occupational health care

TNO Kwaliteit van Leven (author), Nieuwenhuijsen, K. (author), Verbeek, J.H.A.M. (author), de Boer, A.G.E.M. (author), Blonk, R.W.B. (author), van Dijk, F.J.H. (author)

Objectives: This study attempted to determine the factors that best predict the duration of absence from work among employees with common mental disorders. Methods: A cohort of 188 employees, of whom 102 were teachers, on sick leave with common mental disorders was followed for 1 year. Only information potentially available to the occupational...

article 2006

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Dairy consumption and ovarian cancer risk in the Netherlands Cohort Study on diet and cancer

TNO Kwaliteit van Leven TNO Voeding (author), Mommers, M. (author), Schouten, L.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author)

Ovary cancer risk in relation to consumption of dairy products was investigated using a self-administered questionnaire on dietary habits and other risk factors for cancer, which was completed in 1986 by 62 573 postmenopausal women participating in the Netherlands Cohort Study. Follow-up for cancer was implemented by annual record linkage with...

article 2006

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Lipid profile and carotid intima-media thickness in a prospective cohort of very preterm subjects at age 19 years: Effects of early growth and current body composition

TNO Kwaliteit van Leven (author), Finken, M.J.J. (author), Inderson, A. (author), van Montfoort, N. (author), Keijzer-Veen, M.G. (author), van Weert, A.W.M. (author), Çarfil, N. (author), Frölich, M. (author), Hille, E.T.M. (author), Romijn, J.A. (author), Dekker, F.W. (author), Wit, J.M. (author)

Cardiovascular disease (CVD) risk is associated with prenatal and infancy growth. However, the relative importance of these time periods for the CVD risk is uncertain. To elucidate this, we tested in a very preterm cohort the effects of birth weight for gestational age and weight gain between birth and 3 mo post-term (early postnatal weight gain...

article 2006

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Dietary patterns and breast cancer risk: Results from three cohort studies in the DIETSCAN project

Männistö, S. (author), Dixon, L.B. (author), Balder, H.F. (author), Virtanen, M.J. (author), Krogh, V. (author), Khani, B.R. (author), Berrino, F. (author), van den Brandt, P.A. (author), Hartman, A.M. (author), Pietinen, P. (author), Tan, F. (author), Wolk, A. (author), Goldbohm, R.A. (author), TNO Kwaliteit van Leven TNO Voeding (author)

Objective: Only a few consistent findings on individual foods or nutrients that influence breast cancer risk have emerged thus far. Since people do not consume individual foods but certain combinations of them, the analysis of dietary patterns may offer an additional aspect for assessing associations between diet and diseases such as breast...

article 2005