Searched for: subject%3A%22cell%255C%2Bheterogeneity%22
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document
Verhage, B.A.J. (author), Schouten, L.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
Using data collected of a large population-based cohort study, we studied the association between anthropometric factors and the risk of pancreatic cancer. Furthermore, we investigated whether these associations differ among microscopically confirmed pancreatic cancer (MCPC) cases and non-MCPC (NMCPC) cases. The Netherlands Cohort Study on Diet...
article 2007
document
Brama, P.A.J. (author), Tekoppele, J.M. (author), Bank, R.A. (author), Barneveld, A. (author), van Weeren, P.R. (author), Gaubius Instituut TNO (author)
The objective of this study was to document the development of biochemical heterogeneity from birth to maturity in equine articular cartilage, and to test the hypothesis that the amount of exercise during early life may influence this process. Neonatal foals showed no biochemical heterogeneity whatsoever, in contrast to a clear biochemical...
article 2002
document
Vázquez-Martínez, R.M. (author), Malagón, M.M. (author), van Strien, F.J.C. (author), Jespersen, S. (author), van der Greef, J. (author), Roubos, E.W. (author), Gracia-Navarro, F. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
We have previously shown that the melanotrope population of the pituitary intermediate lobe of Rana ridibunda is composed of two subpopulations, of low (LD) and high density (HD), that show distinct ultrastructural features and display different synthetic and secretory rates. To investigate whether LD and HD melanotrope cells also differ in...
article 1999
document
van Delft, J.H.M. (author), Baan, R.A. (author), Roza, L. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
In this review data are summarized on biomarkers that are used for biological effect monitoring of human populations exposed to genotoxic carcinogens. The biomarkers are DNA and protein adducts and cytogenetic effects. Most of these biomarkers are relevant for the process of carcinogenesis. Emphasis is on providing information on the properties...
article 1998
document
Offermans, M.T.C. (author), Struyk, L. (author), de Geus, B. (author), Breedveld, F.C. (author), van den Elsen, P.J. (author), Rozing, J. (author), TNO Preventie en Gezondheid (author)
In order to define the extent of T cell heterogeneity and clonality, unique DNA sequences in the junctional region in rearranged T cell receptor (TcR) genes can be studied. For this purpose we have adapted a non-denaturing nucleic acid gel electrophoresis procedure to detect TcR junctional diversity. Detection of junctional diversity is based...
article 1996
document
Offermans, M.T.C. (author), Sonneveld, R.D. (author), Bakker, E. (author), Deutz-Terlouw, P.P. (author), de Geus, B. (author), Rozing, J. (author), TNO Preventie en Gezondheid (author)
Two nucleic acid gel electrophoresis techniques were tested as a possible tool for analyzing junctional diversity in rearranged T cell receptor (TcR) sequences in order to define the extent of T cell heterogeneity. For this purpose denaturing gradient gel electrophoresis (DGGE) as well as non-denaturing gel electrophoresis (nDGE) techniques have...
article 1995
Searched for: subject%3A%22cell%255C%2Bheterogeneity%22
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