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Smilde, A.K. (author), van der Werf, M.J. (author), Bijlsma, S. (author), van der Werff-van der Vat, B.J.C. (author), Jellema, R.H. (author), TNO Kwaliteit van Leven (author)A general method is presented for combining mass spectrometry-based metabolomics data. Such data are becoming more and more abundant, and proper tools for fusing these types of data sets are needed. Fusion of metabolomics data leads to a comprehensive view on the metabolome of an organism or biological system. The ideas presented draw upon...article 2005
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Centrum voor Stralingsbescherming en Dosimetrie TNO (author), Darroudi, F. (author), Natarajan, A.T. (author), Bentvelzen, P.A.J. (author), Heidt, P.J. (author), van Rotterdam, A. (author), Zoetelief, J. (author), Broerse, J.J. (author)Purpose: To investigate the efficacy of three cytogenetic methods (dicentrics, micronuclei (MN) and premature chromosome condensation (PCC) analysis) for assessment of the unirradiated fraction and the persistence of damage after total-body (TB) and partial-body (PB) irradiation of rhesus monkeys (Macaca mulatta). Materials and methods: Animals...article 1998
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- Bos, R. (author), Nieuwenhuizen, W. (author), Instituut voor Verouderings- en Vaatziekten Onderzoek TNO (author) article 1992
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Medisch Biologisch Laboratorium TNO (author), Laman, J.D. (author), Schellekens, M.M. (author), Abacioglu, Y.H. (author), Lewis, G.K. (author), Tersmette, M. (author), Fouchier, R.A.M. (author), Langedijk, J.P.M. (author), Claassen, E. (author), Boersma, W.J.A. (author)The third variable (V3) domain of the human immunodeficiency virus type 1 (HIV-1) external membrane glycoprotein gp120 is of crucial importance in eliciting neutralizing antibodies in infected persons. Polyclonal (PAb) and monoclonal (MAb) antibodies directed against selected epitopes in the V3 domain are valuable tools for analysis of the...article 1992
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Stevens, W.F. (author), Slaaf, D.W. (author), Hooisma, J. (author), Magchielse, T. (author), Meeter, E. (author), Medisch Biologisch Laboratorium TNO (author)A less complicated source of neurons suitable for this type of studies is the parasympathetic ciliary ganglion. In the pigeon and in the chick this ganglion is known to contain only two classes of neurons, both of which are cholinoceptive and cholinergic and that innervate the muscle fibres of the choroid plexus of the eye, the sphincter iridis...article 1978