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Fluitman, K.S. (author), Wijdeveld, M. (author), Davids, M. (author), van Ruiten, C.C. (author), Reinders, I. (author), Wijnhoven, H.A.H. (author), Keijser, B.J.F. (author), Visser, M. (author), Nieuwdorp, M. (author), IJzerman, R.G. (author)Expert groups argue to raise the recommended daily allowance for protein in older adults from 0.8 to 1.2 g/kg/day to prevent undernutrition. However, protein is thought to increase satiety, possibly through effects on gut microbiota and central appetite regulation. If true, raising daily protein intake may work counterproductively. In a...article 2023
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Vreeken, D. (author), Seidel, F. (author), de La Roij, G. (author), Vening, W. (author), den Hengst, W.A. (author), Verschuren, L. (author), Özsezen, S. (author), Kessels, R.P.C. (author), Duering, M. (author), Mutsaerts, H.J.M.M. (author), Kleemann, R. (author), Wiesmann, M. (author), Hazebroek, E.J. (author), Kiliaan, A.J. (author)BACKGROUND AND OBJECTIVE: While underlying pathophysiology linking obesity to brain health is not completely understood, white adipose tissue (WAT) is considered a key player. In obesity, WAT becomes dysregulated, showing hyperplasia, hypertrophy, and eventually inflammation. This disbalance leads to dysregulated secretion of adipokines...article 2023
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Schuller, A.A. (author), Hoekstra, A.R. (author)Aims. With increasing age, the proportion of older individuals visiting a dental clinic decreases. The aim was to gain insight into a) whether frailty or dental status were associated with visiting a dental clinic and b) their perceived barriers to accessing oral health care. Methods. Individuals eligible for the yearly influenza vaccination in...article 2023
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Ramsey, K.A. (author), Yeung, S.S.Y. (author), Rojer, A.G.M. (author), Gensous, N. (author), Asamane, E.A. (author), Aunger, J.A. (author), Bondarev, D. (author), Cabbia, A. (author), Doody, P. (author), Iadarola, B. (author), Rodrigues, B. (author), Tahir, M.R. (author), Kallen, V. (author), Pazienza, P. (author), Santos, N.C. (author), Sipilä, S. (author), Thompson, J.L. (author), Meskers, C.G.M. (author), rappenburg, M.C. (author), Whittaker, A.C. (author), Maier1, A.B. (author)Purpose: Evidence-based guidelines on nutrition and physical activity are used to increase knowledge in order to promote a healthy lifestyle. However, actual knowledge of guidelines is limited and whether it is associated with health outcomes is unclear. Participants and Methods: This inception cohort study aimed to investigate the association...article 2022
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Shimura, T. (author), Sato, S. (author), Zalar, P. (author), Matsuhisa, N. (author)Wearable technologies are becoming important for the fields of information technology and healthcare, driven mainly by societal issues such as the aging society and the current pandemic. Recently developed flexible/stretchable wearable devices have demonstrated their ability for long-term healthcare monitoring with improved signal integrity and...article 2022
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Streekstra, E.J. (author), Kiss, M. (author), van den Heuvel, J. (author), Nicolaï, J. (author), van den Broek, P. (author), Botden, S.M.B.I. (author), Stommel, M.W.J. (author), van Rijssel, L. (author), Ungell, A.L. (author), van de Steeg, E. (author), Russel, F.G.M. (author), de Wildt, S.N. (author)Little is known about the impact of age on the processes governing human intestinal drug absorption. The Ussing chamber is a system to study drug transport across tissue barriers, but it has not been used to study drug absorption processes in children. This study aimed to explore the feasibility of the Ussing chamber methodology to assess...article 2022
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Jong, J.C.B.C. (author), Attema, B.J. (author), van der Hoek, M.D. (author), Verschuren, L. (author), Caspers, M.P.M. (author), Kleemann, R. (author), van der Leij, F.R. (author), van den Hoek, A.M. (author), Nieuwenhuizen1, A.G. (author), Keijer, J. (author)Sex differences in muscle‐ageing are incompletely understood and could be crucial for the optimalisation of sarcopenia‐related interventions. • Therefore, we performed an observational trial to gain insight in potential sex differences in processes involved in human muscle‐ageing.public lecture 2022
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Kraaijpoel, D.A. (author), Esteves Martins, J.C. (author), Osinga, S. (author), Vogelaar, B.B.S.A. (author), Breunese, J.N. (author)We perform statistical analyses on spatiotemporal patterns in the magnitude distribution of induced earthquakes in the Groningen natural gas field. The seismic catalogue contains 336 earthquakes with (local) magnitudes above , observed in the period between 1 January 1995 and 1 January 2022. An exploratory moving-window analysis of maximum...article 2022
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van Dommelen, P. (author), Arnaud, L. (author), Koledova, E.B. (author)Curve matching may be used to predict growth outcomes using data of patients whose growth curves resemble those of a new patient with growth hormone deficiency (GHD) and those born small for gestational age (SGA). We aimed to investigate the validity of curve matching to predict growth in patients with GHD and those born SGA receiving...article 2022
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Bongers, C.C.W.G. (author), de Korte, J.Q. (author), Zwartkruis, M. (author), Levels, K. (author), Kingma, B.R.M. (author), Eijsvogels, T.M.H. (author)The combination of an exacerbated workload and impermeable nature of the personal protective equipment (PPE) worn by COVID-19 healthcare workers increases heat strain. We aimed to compare the prevalence of heat strain symptoms before (routine care without PPE) versus during the COVID-19 pandemic (COVID-19 care with PPE), identify risk factors...article 2022
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de Verhoeff, M.C. (author), Lobbezoo, F. (author), van Leeuwen, A.M. (author), Schuller, A.A. (author), Koutris, M. (author)Background: Parkinson's disease (PD) is a neurodegenerative condition affecting the quality of life. Due to a worsening of oral health in PD patients with the progression of the disease, oral health-related quality of life (OHRQoL) could be impaired as well. Objectives: To assess whether PD patients in The Netherlands experience worse OHRQoL...article 2022
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van de Ven, D. (author), Robroek, S.J.W. (author), Oude Hengel, K.M. (author), Burdorf, A. (author), Schuring, M. (author)Objectives This study aimed to evaluate the extent to which physical and mental health and body mass index (BMI) changed before, during and after becoming unemployed or employed, and whether these associations differ across psychosocial and physical working conditions. Methods Participants from seven waves (2010–2017) of the Dutch longitudinal...article 2022
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Kocevska, D. (author), Lysen, T.S. (author), Dotinga, A. (author), Koopman-Verhoeff, M.E. (author), Luijk, M.P.C.M. (author), Antypa, N. (author), Biermasz, N.R. (author), Blokstra, A. (author), Brug, J. (author), Burk, W.J. (author), Comijs, H.C. (author), Corpeleijn, E. (author), Dashti, H.S. (author), de Bruin, E.J. (author), de Graaf, R. (author), Derks, I.P.M. (author), Dewald-Kaufmann, J.F. (author), Elders, P.J.M. (author), Gemke, R.J.B.J. (author), Grievink, L. (author), Hale, L. (author), Hartman, C.A. (author), Heijnen, C.J. (author), Huisman, M. (author), Huss, A. (author), Ikram, M.A. (author), Jones, S.E. (author), Klein Velderman, M. (author), Koning, M. (author), Meijer, A.M. (author), Meijer, K. (author), Noordam, R. (author), Oldehinkel, A.J. (author), Groeniger, J.O. (author), Penninx, B.W.J.H. (author), Picavet, H.S.J. (author), Pieters, S. (author), Reijneveld, S.A. (author), Reitz, E. (author), Renders, C.M. (author), Rodenburg, G. (author), Rutters, F. (author), Smith, M.C. (author), Singh, A.S. (author), Snijder, M.B. (author), Stronks, K. (author), ten Have, M, (author), Twisk, J.W.R. (author), van de Mheen, D. (author), van der Ende, J. (author), van der Heijden, K.B. (author), van der Velden, P.G. (author), van Lenthe, F.J. (author), van Litsenburg, R.R.L (author), van Oostrom, S.H. (author), van Schalkwijk, F.J. (author), Sheehan, CM, (author), Verheij, RA, (author), Verhulst, F.C. (author), Vermeulen, M.C.M. (author), Vermeulen, R.C.H. (author), Verschuren, W.M.M. (author), Vrijkotte, T.G.M. (author), Wijga, A.H. (author), Willemen, A.M. (author), ter Wolbeek, M. (author), Wood, A.R. (author), Xerxa, Y. (author), Bramer, W.M. (author), Franco, O.H. (author), Luik, A.I. (author), van Someren, E.J.W. (author), Tiemeier, H. (author)We aimed to obtain reliable reference charts for sleep duration, estimate the prevalence of sleep complaints across the lifespan and identify risk indicators of poor sleep. Studies were identified through systematic literature search in Embase, Medline and Web of Science (9 August 2019) and through personal contacts. Eligible studies had to be...article 2021
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Pak, K. (author), Kooij, D.T.A.M. (author), de Lange, A.H. (author), van den Heuvel, S.G. (author), Veldhoven, M.J.P.M. (author)Organisations are challenged to extend working lives of older workers. However, there is little empirical evidence available on how organisations should do this. This study aims to fill this gap by testing the effect of Human Resource (HR) practices on perceived work ability and the preferred retirement age. Based on the Conversation of...article 2021
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Kallen, V. (author), Tahir, M. (author), Bedard A., (author), Bongers, B. (author), van Riel, N. (author), van Meeteren, N. (author)Allostatic load reflects the cumulative strain on organic functions that may gradually evolve into overt disease. Our aim was to evaluate the allostatic parameters in the context of aging, and identify the parameters that may be suitable for an allostatic load index for elderly people (>60 years). From previously published studies, 11 allostatic...article 2021
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Weening-Verbree, L.F. (author), Schuller, A.A. (author), Cheung, S.L. (author), Zuidema, S.U. (author), van der Schans, C.P. (author), Hobbelen, J.S.M.H. (author)Objectives to explore attitudes, perceptions, and perceived barriers to and the perceived facilitators of daily oral health care and the actual daily oral health care performances among nursing home staff. Methods A mixed methods study in 21 nursing homes was completed; a) questionnaires for nursing staff and managers; b) focus group interviews...article 2021
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Xu, S. (author), Liu, X. (author), Tabaković, A. (author), Lin, P. (author), Zhang, Y. (author), Nahar, S. (author), Lommerts, B.J. (author), Schlangen, E. (author)Rejuvenator encapsulation technique showed great potential for extrinsic asphalt pavement damage healing. Once the capsules are embedded within asphalt pavement, the healing is activated on-demand via progressing microcrack. When the microcrack encounters the capsule, the fracture energy at the tip opens the capsule and releases the rejuvenator....article 2021
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Regeer, H. (author), Nieuwenhuijse, E.A. (author), Vos, R.C. (author), Kiefte-de Jong, J.C. (author), van Empelen, P. (author), de Koning, E.J.P. (author), Bilo, H.J.G. (author), Huisman, S.D. (author)Aims: To investigate changes in physical activity (PA) and psychological factors during societal lockdown in people with type 2 diabetes. Methods: A cross-sectional study among Dutch adults with type 2 diabetes. Data were collected using online questionnaires. A multivariate multinomial logistic regression was performed with change in PA during...article 2021
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Austin, P.C. (author), White, I.R. (author), Lee, D.S. (author), van Buuren, S. (author)Missing data is a common occurrence in clinical research. Missing data occurs when the value of the variables of interest are not measured or recorded for all subjects in the sample. Common approaches to addressing the presence of missing data include complete-case analyses, in which subjects with missing data are excluded, or mean-value...article 2021
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Munsterman, D.K. (author), Deckers, J. (author)Based on palynologic interpretations, the Oligocene/Miocene boundary was identified in the cored samples of the ON-Mol-1 and Weelde boreholes in the southern North Sea Basin. In both boreholes, the presumed location of the Oligocene/Miocene boundary is marked by a thin gravel bed, which testifies of a hiatus, within a continuation of shelly,...article 2020