Searched for: subject:"adolescent"
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Männistö, S. (author), Yaun, S.S. (author), Hunter, D.J. (author), Spiegelman, D. (author), Adami, H.O. (author), Albanes, D. (author), van den Brandt, P.A. (author), Buring, J.E. (author), Cerhan, J.R. (author), Colditz, G.A. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Harnack, L. (author), Leitzmann, M. (author), McCullough, M.L. (author), Miller, A.B. (author), Rohan, T.E. (author), Schatzkin, A. (author), Virtamo, J. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)
Dietary carotenoids have been hypothesized to protect against epithelial cancers. The authors analyzed the associations between intakes of specific carotenoids (alpha-carotene, beta-carotene, beta-cryptoxanthin, lutein + zeaxanthin, and lycopene) and risk of colorectal cancer using the primary data from 11 cohort studies carried out in North...
article 2007
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Fabriek, B.O. (author), Møller, H.J. (author), Vloet, R.P.M. (author), van Winsen, L.M. (author), Hanemaaijer, R. (author), Teunissen, C.E. (author), Uitdehaag, B.M.J. (author), van den Berg, T.K. (author), Dijkstra, C.D. (author), TNO Kwaliteit van Leven (author)
The scavenger receptor CD163 is selectively expressed on tissue macrophages and human monocytes. CD163 has been implicated to play a role in the clearance of hemoglobin and in the regulation of cytokine production by macrophages. Membrane CD163 can be cleaved by matrix metalloproteinases (MMP) resulting in soluble CD163 (sCD163). In the present...
article 2007
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Reijneveld, S.A. (author), Harland, P. (author), Brugman, E. (author), Verhulst, F.C. (author), Verloove-Vanhorick, S.P. (author)
Background This study aims to examine a) the prevalence of psychosocial problems and b) the association between parent-reported problems and the identification by doctors and nurses (child health professionals, CHP) working in preventive child health care, among immigrant and non-immigrant children. Methods CHPs examined 4,098 children aged 5...
article 2005
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Visser, J. (author), Lentjes, E. (author), Haspels, I. (author), Graffelman, W. (author), Blauw, B. (author), de Kloet, R. (author), Nagelkerken, L. (author), TNO Preventie en Gezondheid (author)
Background: In this study we tested the hypothesis that the increased sensitivity to glucocorticoids in chronic fatigue syndrome (CFS)-patients can be attributed to an altered functioning of their glucocorticoid receptors (GR). Methods: For this purpose, affinity and distribution of the GR were studied in purified, peripheral blood mononuclear...
article 2001
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van Strien, T. (author), Herman, C.P. (author), Verheijden, M.W. (author), TNO Kwaliteit van Leven (author)
This study examined which individuals in particular are susceptible or resistant to develop overweight in our current obesogenic environment. A cross-sectional study was conducted in a sample of 1342 people representative of the general population in the Netherlands. Overweight-level (normal body weight ≥ 17.5 BMI [weight in kilograms/height in...
article 2009
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Chorus, A.M.J. (author), Miedema, H.S. (author), Boonen, A. (author), van der Linden, S. (author)
Objective: To investigate the relationship between work and quality of life (QOL) in patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS) aged 16-59. Methods: 1056 patients with RA and 658 with AS were included in the study. Data were obtained by postal questionnaire, which included severa generic and disease related QOL...
article 2003
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Robitail, S. (author), Simeoni, M.-C. (author), Erhart, M. (author), Ravens-Sieberer, U. (author), Bruil, J. (author), Auquier, P. (author), TNO Preventie en Gezondheid (author)
Purpose: The KIDSCREEN project aims to develop a European cross-cultural generic self-administered Health-Related Quality of Life (HRQoL) instrument for children and adolescents. Proxy measures HRQoL should be a useful and practical alternative to assess children's HRQoL. The KIDSCREEN pilot study involved 3988 children and 2526 child-proxy...
article 2006
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van der Laan, W. (author), Molenaar, E. (author), Ronday, K. (author), Verheijen, J. (author), Breedveld, F. (author), Greenwald, R. (author), Dijkmans, B. (author), Tekoppele, J. (author), Gaubius instituut TNO (author)
Objective. To investigate the effects of doxycycline on disease activity and joint destruction in patients with rheumatoid arthritis (RA). Methods. A 36 week double blind, placebo controlled crossover trial was conducted. Patients (n = 66) received 50 mg doxycycline or placebo twice a day during 12, 24, or 36 weeks. Patient assessments were...
article 2001
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van der Pal-de Bruin, K.M. (author), van der Pal, S.M. (author), Verloove-Vanhoricka, S.P. (author), Walther, F.J. (author)
In 1983, data of a unique nationwide cohort of 1338 very preterm (< 32 weeks of gestation) or VLBW (birth weight < 1500 g) infants in the Netherlands was collected and followed at several ages until they reached the age of 19 years. At 19 years of age a more extensive follow-up study was done, including questionnaires, tests on a computer and a...
article 2015
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Hosli, E. (author), Detmar, S. (author), Raat, H. (author), Bruil, J. (author), Vogels, T. (author), Verrips, E. (author), TNO Kwaliteit van Leven (author)
The Child Health Questionnaire (CHQ)-87-item child and adolescent self-report (CF87) is an increasingly used health-related quality-of-life instrument for measuring the self-perceived physical and psychosocial well-being of children aged 10 years and older. The aims of this study were to evaluate structure, reliability and validity of the Dutch...
article 2007
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Kennedy, S. (author), Jin, X. (author), Yu, H. (author), Zhong, S. (author), Magill, P. (author), van Vliet, T. (author), Kistemaker, C. (author), Voors, C. (author), Pasman, W. (author), TNO Kwaliteit van Leven (author)
A proof-of-concept study to assess the safety and efficacy of a traditional Chinese medicine formula as treatment for primary dysmenorrhea showed no statistically significant benefit over placebo. However, some efficacy parameters suggested possible superiority of the active treatment and so a larger study needs to be performed to determine...
article 2006
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Ruwaard, D. (author), Gijsen, R. (author), Bartelds, A.I.M. (author), Hirasing, R.A. (author), Verkleij, H. (author), Kromhout, D. (author), TNO Preventie en Gezondheid (author)
OBJECTIVE - To assess possible changes in the incidence of diabetes in all age-groups in The Netherlands during a 10-year period (1980-1983/1990-1992). RESEARCH DESIGN AND METHODS - Since 1970, a network of sentinel stations (the Dutch Sentinel Practice Network) consisting of ∼1% of the Dutch population has been in operation to gain insight into...
article 1996
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de Jong-de Vos Van Steenwijk, C.C.E. (author), Wieling, W. (author), Harms, M.P.M. (author), Wesseling, K.H. (author), TNO Biomedical Instrumentation (author)
1. Fainting is a common phenomenon in young subjects, but the final events before the actual faint are not well known. The aim of the present study was to study the inter-individual variability of haemodynamic events associated with near-fainting in children and teenagers. 2. Sixty-eight healthy subjects (aged 6-16 years) performed a 70°tilt-up...
article 1997
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Böhm, F.J. (author), Hirasing, R.A. (author), Vaandrager, G.J. (author), Reeser, H.M. (author), Bijlsma, F. (author), de Groot, R.M. (author), TNO Preventie en Gezondheid (author)
Objective. To determine the mortality of insulin-dependent diabetes mellitus in the age group of 0-19 year over the period 1988-1990 and to compare these data with those of ten years ago. Design. Retrospective. Setting. The Netherlands. Method. The number of deaths was obtained by using the data of the death certificate registers of the Central...
article 1996
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Valk, P.J.L. (author), van Roon, D.B. (author), Simons, M. (author), Rikken, G. (author)
Sustained vigilance is required by pilots and crew during flight; therefore, the use of antihistamines with sedating properties is widely prohibited. The purpose of this study was to determine the effects of desloratadine, a long-acting, nonsedating antihistamine, on healthy volunteers placed under conditions of simulated cabin pressure. Methods...
article 2004
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Verhoef, P. (author), van Vliet, T. (author), Olthof, M.R. (author), Katan, M.B. (author), TNO Kwaliteit van Leven (author)
Background: A high plasma concentration of total homocysteine (tHcy) is associated with increased risk of cardiovascular disease. A high protein intake and hence a high intake of methionine-the sole dietary precursor of homocysteine-may raise plasma tHcy concentrations. Objectives: We studied whether high intake of protein increases plasma...
article 2005
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Houtman, I.L.D. (author), Bongers, P.M. (author), Smulders, P.G.W. (author), Kompier, M.A.J. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)
Objectives - This paper examines the relationship between work stressors and the following health indicators: psychosomatic complaints, health behavior, and musculoskeletal problems. Methods - Secondary analyses were performed on data from the National Work and Living Condition Survey, which provides a representative sample of the working...
article 1994
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Treurniet, H.F. (author), Davidse, W. (author), TNO Preventie en Gezondheid (author)
In 1983 werd door de Geneeskundige Hoofdinspectie (GHI) een landelijke registratie van seksueel overdraagbare aandoeningen (SOA's) ingevoerd, naast het registratiesysteem van wettelijk aangifteplichtige ziekten. De gegevens voor de registratie worden door sociaal-verpleegkundigen, werkzaam bij GGD'en en geslachtsziekten-poliklinieken, verzameld....
article 1993
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Haverkate, F. (author), Samama, M. (author), TNO Preventie en Gezondheid (author)
Approximately 250 cases of dysfibrinogenemia have been reported; 55% were asymptomatic (detected by chance), 25% had a tendency to bleeding, and 20% were reported to have a tendency to thrombosis. To establish a possible association between familial dysfibrinogenemia and thrombophilia, data on cases with both affections were collected in a study...
article 1995
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Kluft, C. (author), Meijer, P. (author), LaGuardia, K.D. (author), Fisher, A.C. (author), TNO Kwaliteit van Leven (author)
Purpose: The aim of this study was to compare effects of the transdermal contraceptive patch, a desogestrel/ethinyl estradiol (EE)-containing, monophasic combination oral contraceptive (COC) and a levonorgestrel/EE-containing, triphasic COC on hemostasis variables. Study Design: This was a randomized, open-label study of 104 young women who...
article 2008
Searched for: subject:"adolescent"
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