Searched for: subject:"adolescent"
(1 - 20 of 85)

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van den Broek, T.J. (author), Bakker, G.C.M. (author), Rubingh, C.M. (author), Bijlsma, S. (author), Stroeve, J.H.M. (author), van Ommen, B. (author), van Erk, M.J. (author), Wopereis, S. (author)
Background: A key feature of metabolic health is the ability to adapt upon dietary perturbations. A systemic review defined an optimal nutritional challenge test, the "PhenFlex test" (PFT). Recently, it has been shown that the PFT enables the quantification of all relevant metabolic processes involved in maintaining or regaining homeostasis of...
article 2017
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de Lijster, G.P.A. (author), Felten, H. (author), Kok, G. (author), Kocken, P.L. (author)
Many adolescents experience sexual harassment and victims of sexual harassment have higher risks regarding well-being and health behaviors such as higher risks of suicidal thoughts, suicidal ideation and feeling unsafe at school. A peer-performed play and school lessons on preventing sexual harassment behavior were presented to secondary school...
article 2016
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Vlaming, M.L. (author), van Duijn, E. (author), Dillingh, M.R. (author), Brands, R. (author), Windhorst, A.D. (author), Hendrikse, N.H. (author), Bosgra, S. (author), Burggraaf, J. (author), de Koning, M.C. (author), Fidder, A. (author), Mocking, J.A. (author), Sandman, H. (author), de Ligt, R.A. (author), Fabriek, B.O. (author), Pasman, W.J. (author), Seinen, W. (author), Alves, T. (author), Carrondo, M. (author), Peixoto, C. (author), Peeters, P.A. (author), Vaes, W.H. (author)
Preclinical development of new biological entities (NBEs), such as human protein therapeutics, requires considerable expenditure of time and costs. Poor prediction of pharmacokinetics in humans further reduces net efficiency. In this study, we show for the first time that pharmacokinetic data of NBEs in humans can be successfully obtained early...
article 2015
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Schönbeck, Y. (author), van Dommelen, P. (author), Hirasing, R.A. (author), van Buuren, S. (author)
Objectives To study trends in height of Turkish and Moroccan immigrant children living in The Netherlands, to investigate the association between height and background characteristics in these children, and to calculate height-for-age-references data for these groups. Design Nationwide cross-sectional data collection from children aged 0 to 18...
article 2015
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Hayes, D.J. (author), van Buuren, S. (author), ter Kuile, F.O. (author), Stasinopoulos, D.M. (author), Rigby, R.A. (author), Terlouw, D.J. (author)
Methods: A weight-for-age database was constructed from pre-existing population-based anthropometric data obtained from household surveys and research groups. It contained data collected between 1995 and 2012 on 1 263 119 individuals (909 368 female, 353 751 male) older than 14 days and younger than 50 years in 64 malaria-endemic countries....
article 2015
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Hendriksen, M.A.H. (author), Verkaik-Kloosterman, J. (author), Noort, M.W. (author), van Raaij, J.M.A. (author)
Background/objectives: Sodium intake in the Netherlands is substantially above the recommended intake of 2400 mg/day. This study aimed to estimate the effect of two sodium reduction strategies, that is, modification of the composition of industrially processed foods toward the technologically feasible minimum level or alteration of consumers’...
article 2015
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Koopmans, L. (author), Bernaards, C.M. (author), Hildebrandt, V.H. (author), de Vet, H.C.W. (author), van der Beek, A.J. (author)
OBJECTIVE:: To examine the construct validity of the Individual Work Performance Questionnaire (IWPQ). METHODS:: A total of 1424 Dutch workers from three occupational sectors (blue, pink, and white collar) participated in the study. First, IWPQ scores were correlated with related constructs (convergent validity). Second, differences between...
article 2014
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de Kock, K.A. (author), Steenbeek, R. (author), Buijs, P.C. (author), Lucassen, P.L. (author), Knottnerus, J.A. (author), Lagro-Janssen, A.L. (author)
Background. Work and being able to work are important prerequisites for health and well being. Health problems can have a negative influence on the ability to work and not being able to work can be detrimental for patients’ psychosocial well being. Although GPs are aware of this importance they do not always structurally pay attention to...
article 2014
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Bannink, E.M.N. (author), van Sassen, C. (author), van Buuren, S. (author), de Jong, F.H. (author), Lequin, M. (author), Mulder, P.G.H. (author), de Muinck Keizer-Schrama, S.M.P.F. (author), TNO Kwaliteit van Leven (author)
Background: Besides short stature, gonadal dysgenesis leading to a lack of oestrogen is one of the main characteristics of Turner syndrome (TS). In most TS girls, puberty is induced with exogenous oestrogens. Objective: To describe the pubertal development and uterine dimensions achieved by low-dose 17β-oestradiol (17β-E2) orally started at an...
article 2009
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Grote, F.K. (author), Oostdijk, W. (author), de Muinck Keizer-Schrama, S.M.P.F. (author), van Dommelen, P. (author), van Buuren, S. (author), Dekker, F.W. (author), Ketel, A.G. (author), Moll, H.A. (author), Wit, J.M. (author), TNO Kwaliteit van Leven (author)
Background: As abnormal growth might be the first manifestation of undetected diseases, it is important to have accurate referral criteria and a proper diagnostic work-up. In the present paper we evaluate the diagnostic work-up in secondary health care according to existing consensus guidelines and study the frequency of underlying medical...
article 2008
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Beulens, J.W.J. (author), de Zoete, E.C. (author), Kok, F.J. (author), Schaafsma, G. (author), Hendriks, H.F.J. (author), TNO Kwaliteit van Leven (author)
Objective: Moderate alcohol consumption is associated with a decreased risk of type II diabetes. This study investigates the effect of moderate alcohol consumption on adipokines and insulin sensitivity. Subjects: Twenty healthy, lean (body mass index (BMI) 18.5-25 kg/m2; n=11) or overweight (BMI>27 kg/m2; n=9) men (18-25 years). Methods: Three...
article 2008
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Sivan, S.-S. (author), Wachtel, E. (author), Tsitron, E. (author), Sakkee, N. (author), van der Ham, F. (author), de Groot, J. (author), Roberts, S. (author), Maroudas, A. (author), TNO Kwaliteit van Leven (author)
Knowledge of rates of protein turnover is important for a quantitative understanding of tissue synthesis and catabolism. In this work, we have used the racemization of aspartic acid as a marker for the turnover of collagen obtained from healthy and pathological human intervertebral disc matrices. We measured the ratio of the D- and L-isomers in...
article 2008
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Baston, H. (author), Rijnders, M. (author), Green, J. (author), Buitendijk, S. (author), TNO Kwaliteit van Leven (author)
In 2003 research was conducted in England (n=738) to further our understanding of factors that relate to women's longer-term appraisal of their birth experience. Women's appraisals are likely to be influenced by the culture in which they give birth and the predominant norms at that time. To explore this further, the study was replicated in the...
article 2008
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Draisma, H.H.M. (author), Reijmers, T.H. (author), Bobeldijk - Pastorova, I. (author), Meulman, J.J. (author), van Estourgie - Burk, G.F. (author), Bartels, M. (author), Ramaker, R. (author), van der Greef, J. (author), Boomsma, D.I. (author), Hankemeier, T. (author), TNO Kwaliteit van Leven (author)
Differences in genetic background and/or environmental exposure among individuals are expected to give rise to differences in measurable characteristics, or phenotypes. Consequently, genetic resemblance and similarities in environment should manifest as similarities in phenotypes. The metabolome reflects many of the system properties, and is...
article 2008
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Verheijden, M.W. (author), Jans, M.P. (author), Hildebrandt, V.H. (author), Hopman-Rock, M. (author), TNO Kwaliteit van Leven (author)
Background: In recent years, many tailored lifestyle counseling programs have become available through the Internet. Previous research into such programs has shown selective enrollment of relatively healthy people. However, because of the known dose-response relationship between the intensity and frequency of counseling and the behavior change...
article 2007
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van der Meer, V. (author), van Stel, H.F. (author), Detmar, S.B. (author), Otten, W. (author), Sterk, P.J. (author), Sont, J.K. (author), TNO Kwaliteit van Leven (author)
Background: Internet and short message service are emerging tools for chronic disease management in adolescents, but few data exist on the barriers to and benefits of internet-based asthma self-management. Our objective was to reveal the barriers and benefits perceived by adolescents with well-controlled and poorly controlled asthma to current...
article 2007
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van Dellen, Q.M. (author), Stronks, K. (author), Bindels, P.J.E. (author), Öry, F.G. (author), Bruil, J. (author), van Aalderen, W.M.C. (author), TNO Kwaliteit van Leven (author)
To identify factors associated with asthma control in a multi-ethnic paediatric population. We interviewed 278 children with paediatrician diagnosed asthma (aged 7-17 years) and one of their parents. Asthma control was assessed with the Asthma Control Questionnaire (ACQ). Detailed information about sociodemographic variables, asthma medication,...
article 2007
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Beckers, D.G.J. (author), van der Linden, D. (author), Smulders, P.G.W. (author), Kompier, M.A.J. (author), Taris, T.W. (author), van Yperen, N.W. (author), TNO Kwaliteit van Leven (author)
Objectives: This study aimed at disentangling the effects of overtime hours from those of long workhours. For part-time workers, overtime work is not intertwined with long workhours as it is for full-time workers. Therefore, part-time and full-time employees were compared with regard to the association between overtime and well-being (fatigue...
article 2007
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Jans, M.P. (author), van den Heuvel, S.G. (author), Hildebrandt, V.H. (author), Bongers, P.M. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE: To determine the relation between body mass index (BMI) and absenteeism. METHODS: Data were collected in a prospective cohort study (n = 1284). Multilevel analyses (linear mixed model with random intercept) with two levels (employee and company) were used to test whether BMI was related to duration and frequency of absenteeism and...
article 2007
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Ravens-Sieberer, U. (author), Auquier, P. (author), Erhart, M. (author), Gosch, A. (author), Rajmil, L. (author), Bruil, J. (author), Power, M. (author), Duer, W. (author), Cloetta, B. (author), Czemy, L. (author), Mazur, J. (author), Czimbalmos, A. (author), Tountas, Y. (author), Hagquist, C. (author), Kilroe, J. (author), Fuerth, K. (author), Czerny, L. (author), Simeoni, M.C. (author), Robitail, S. (author), Nickel, J. (author), Kurth, B.-M. (author), von Rüden, U. (author), Dimitrakakis, C. (author), Aszman, A. (author), Flannery, E. (author), Detmar, S. (author), Veripps, E. (author), Mierzejeswka, E. (author), Berra, S. (author), Tebé, C. (author), Herdman, M. (author), Alonso, J. (author), Abel, T. (author), Bisegger, C. (author), Farley, C. (author), Atherton, C. (author), Phillips, K. (author), TNO Kwaliteit van Leven (author)
Objective: To assess the construct and criterion validity of the KIDSCREEN-27 health-related quality of life (HRQoL) questionnaire, a shorter version of the KIDSCREEN-52. Methods: The five-dimensional KIDSCREEN-27 was tested in a sample of 22,827. For criterion validity the correlation with and the percentage explained variance of the scores of...
article 2007
Searched for: subject:"adolescent"
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