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Vos, P. (author), Intema, F. (author), van El, B. (author), de Groot, J. (author), Bijlsma, J.W.J. (author), Lafeber, F. (author), Mastbergen, S. (author), TNO Kwaliteit van Leven (author)Many animal models are used to study osteoarthritis (OA). In these models the role of joint loading in the development of OA is not fully understood. We studied the effect of loading on the development of OA in the canine Groove-model. In ten female beagle dogs OA was induced in one knee according to the Groove-model. The animals were divided in...article 2009
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Philippens, M.M.G.M. (author), Wismans, J.S.H.M. (author), Forbes, P.A. (author), Yoganandan, N. (author), Pintar, F. (author), Soltis, S.J. (author), TNO Defensie en Veiligheid TNO Industrie en Techniek (author)Injury assessment reference values (IARV) predicting neck injuries are currently not available for side facing seated aircraft passengers in crash conditions. The aircraft impact scenario results in inertial loading of the head and neck, a condition known to be inherently different from common automotive side impact conditions as crash pulse and...article 2009
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de Korte, E.M. (author), de Kraker, H. (author), Bongers, P.M. (author), van Lingen, P. (author), TNO Kwaliteit van Leven (author)To study the effects of a tactile feedback signal in a computer mouse on reduction of hovering behaviour and consequently on changes in muscle load, productivity, comfort and user friendliness, a comparative, experimental study with repeated measures was conducted. Fifteen subjects performed five trials with different mouse actions and a...article 2008
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Faber, G.S. (author), Kingma, I. (author), Delleman, N. (author), van Dieën, J. (author)This study investigated the effects of ship motion on peak spinal loading during lifting. All measurements were done on a ship at sea. In 1-min trials, which were repeated over a wide range of sailing conditions, subjects lifted an 18 kg box five times. Ship motion, whole body kinematics, ground reaction forces and electromyography were measured...article 2008
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Visser, B. (author), Nielsen, P.K. (author), de Kraker, H. (author), Smits, M. (author), Jensen, B.R. (author), Veeger, D. (author), van Dieën, J.H. (author), TNO Kwaliteit van Leven (author), KvL (author)The object of the current study was to determine whether static contraction of proximal musculature has an effect on the blood flow more distally in the upper extremity. Static contractions of muscles in the neck shoulder region at three levels (relaxed, shoulders elevated and shoulders elevated loaded with 4.95 kg each) were combined with...article 2006
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van der Harst, M.R. (author), de Groot, J. (author), Kiers, G.H. (author), Brama, P.A.J. (author), van de Lest, C.H.A. (author), van Weeren, P.R. (author)Objective - To assess whether site-related changes in biochemical composition are present in the cartilage and subchondral and trabecular bone of the metacarpophalangeal joint of horses with early osteoarthritis. Sample population - Right metacarpophalangeal joints from 59 mature warmblood horses. Procedure - Biochemical data (cross-link, amino...article 2005
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Hoozemans, M.J.M. (author), Visser, B. (author), Huysmans, M.A. (author), Speklé, E.M. (author), van Dieën, J.H. (author), TNO Arbeid (author)This paper presents an overview of theories concerning the development of RSI (repetitive strain injury), related to muscle disorders. Movement is a noisy process. The level of noise is affected by factors such as fatigue and psychosocial stress. In order for precision movements to be made in such situations, an increased level of muscle...article 2005
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Hoozemans, M.J.M. (author), de Looze, M.P. (author), Kingma, I. (author), Reijneveld, K.C.N. (author), de Korte, E.M. (author), van der Grinten, M.P. (author), van Dieën, J.H. (author), TNO Kwaliteit van Leven (author)The objective of the present study was to compare energetic workload, perceived exertion, perceived discomfort, safety, and mechanical load at lower limb joints among window cleaners during usage of extension ladders with 30 and 35 cm rung separation. Eleven healthy male professional window cleaners of short and tall stature participated in this...article 2005
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Hernandez, C.J. (author), Tang, S.Y. (author), Baumbach, B.M. (author), Hwu, P.B. (author), Sakkee, A.N. (author), van der Ham, F. (author), de Groot, J. (author), Bank, R.A. (author), Keaveny, T.M. (author), TNO Preventie en Gezondheid (author)The propensity of individual trabeculae to fracture (microfracture) may be important clinically since it could be indicative of bone fragility. Whether or not an overloaded trabecula fractures is determined in part by its structural ductility, a mechanical property that describes how much deformation a trabecula can sustain. The overall goal of...article 2005
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Heinrich, J. (author), Blatter, B.M. (author), Bongers, P.M. (author)Aim: To compare two different methods for assessment of postural load and duration of computer use in office workers. Methods: The study population existed of 87 computer workers. Questionnaire data about exposure were compared with exposures measured by a standardised or objective method. Measuring true exposure to postural load consisted of an...article 2004
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van der Harst, M.R. (author), Brama, P.A.J. (author), van de Lest, C.H.A. (author), Kiers, G.H. (author), de Groot, J. (author), van Weeren, P.R. (author), TNO Kwaliteit van Leven (author)Objective: In articular joints, the forces generated by locomotion are absorbed by the whole of cartilage, subchondral bone and underlying trabecular bone. The objective of this study is to test the hypothesis that regional differences in joint loading are related to clear and interrelated differences in the composition of the extracellular...article 2004
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Zhu, Q. (author), de With, G. (author), Dortmans, L.J.M.G. (author), Feenstra, F. (author)The purpose of this study is to investigate the subcritical crack growth (SCG) behavior of alumina-glass dental composites. Alumina-glass composites were fabricated by infiltrating molten glass to porous alumina preforms. Rectangular bars of the composite were subject to dynamic loading in air, with stressing rates ranging from 0.01 MPa/s to 2...article 2003
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Verver, M.M. (author), van Hoof, J.F.A.M. (author), Oomens, C.W.J. (author), van de Wouw, N. (author), Wismans, J.S.H.M. (author)Objective. This paper describes the prediction of spinal forces in car occupants during vertical vibrations using a numerical multi-body occupant model. Background. An increasing part of the population is exposed to whole body vibrations in vehicles. In literature, vertical vibrations and low back pain are often related to each other. The cause...article 2003
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Hoogendoorn, W.E. (author), Bongers, P.M. (author), de Vet, H.C.W. (author), Twisk, J.W.R. (author), van Mechelen, W. (author), Bouter, L.M. (author), TNO Arbeid (author)Aims: To compare the results of a traditional approach using standard regression for the analysis of data from a prospective cohort study with the results of generalised estimating equations (GEE) analysis. Methods: The research was part of a three year prospective cohort study on work related risk factors for low back pain. The study population...article 2002
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Marijnissen, A.C.A. (author), van Roermund, P.M. (author), TeKoppele, J.M. (author), Bijlsma, J.W.J. (author), Lafeber, F.P.J.G. (author), TNO Preventie en Gezondheid (author)Objective: The frequently used anterior cruciate ligament transection (ACLT) model of osteoarthritis (OA) in the dog, makes use of a permanent trigger (joint instability) for inducing degenerative changes. The present study evaluates a canine model of degenerative cartilage damage, mimicking OA, which is induced without making use of permanent...article 2002
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Hoogendoorn, W.E. (author), Bongers, P.M. (author), de Vet, H.C.W. (author), Ariëns, G.A.M. (author), van Mechelen, W. (author), Bouter, L.M. (author)Objective: To determine whether physical and psychosocial load at work influence sickness absence due to low back pain. Methods: The research was a part of the study on musculoskeletal disorders, absenteeism, stress, and health (SMASH), a 3 year prospective cohort study on risk factors for musculoskeletal disorders. Workers from 21 companies...article 2002
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Brama, P.A.J. (author), TeKoppele, J.M. (author), Bank, R.A. (author), Barneveld, A. (author), van Weeren, P.R. (author), Gaubius instituut TNO (author)Subchondral bone provides structural support to the overlying articular cartilage, and plays an important role in osteochondral diseases. There is growing insight that the mechanical features of bone are related to the biochemistry of the collagen network and the mineral content. In the present study, part of the normal developmental process and...article 2002
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Hildebrandt, V.H. (author), Bongers, P.M. (author), van Dijk, F.J. (author), Kempers, H.C.G. (author), Dul, J. (author)The article describes the Dutch Musculoskeletal Questionnaire (DMQ) for the analysis of musculoskeletal workload and associated potential hazardous working conditions as well as musculoskeletal symptoms in worker populations. Its qualities are explored using a database of 1,575 workers in various occupations who completed the questionnaire. The...article 2001
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de Looze, M.P. (author), Steenhuizen, S. (author), Boeken-Kruger, M.C. (author), Baten, C.T.M. (author), Kingma, I. (author), van Dieën, J.H. (author)People who know the actual mass of an object to be lifted normally prepare themselves before attempting a lift to control the movement and to minimize low back loading. In this study, the trunk muscular reactions and low back torque were investigated in the situation in which the individual did not know the actual mass but only had some idea of...article 2000
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Hoogendoorn, W.E. (author), Bongers, P.M. (author), de Vet, H.C.W. (author), Douwes, M. (author), Koes, B.W. (author), Miedema, M.C. (author), Ariëns, G.A.M. (author), Bouter, L.M. (author)Study Design: A 3-year prospective cohort study among workers of 34 companies in the Netherlands. Objectives: To investigate the relation between flexion and rotation of the trunk and lifting at work and the occurrence of low back pain. Summary of Background Data: Previous studies on work-related physical risk factors for low back pain either...article 2000
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