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Børsting, T. (author), Schuller, A.A. (author), van Dommelen, P. (author), Stafne, S.N. (author), Skeie, M.S. (author), Skaare, A.B. (author), Mørkved, S. (author), Salvesen, K.A. (author), Stunes, A.K. (author), Mosti, M.P. (author), Gustafsson, M.K. (author), Syversen, U. (author), Fagerhaug, T.N. (author)Purpose The study aimed to investigate associations between maternal vitamin D status during pregnancy and molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM) among children. Methods The study had a longitudinal design using prospectively collected data from 176 mother and child pairs. Mothers were initially...article 2022
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Rafiq, R. (author), Aleva, F.E. (author), Schrumpf, J.A. (author), Daniels, J.M. (author), Bet, P.M. (author), Boersma, W.G. (author), Bresser, P. (author), Spanbroek, M. (author), Lips, P. (author), van den Broek, T.J. (author), Keijser, B.J.F. (author), van der Ven, J.A.M. (author), Hiemstra, P.S. (author), den Heijer, M. (author), de Jongh, R.T. (author), PRECOVID-study group, (author)Background. Vitamin D deficiency is frequently found in patients with chronic obstructive pulmonary disease (COPD). Vitamin D has antimicrobial, anti-inflammatory, and immunomodulatory effects. Therefore, supplementation may prevent COPD exacerbations, particularly in deficient patients. Objectives. We aimed to assess the effect of vitamin D...article 2022
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Offringa, A.K. (author), Bourgonje, A.R. (author), Schrier, M.S. (author), Deth, R.C. (author)Vitamin B12 is a redox-active compound containing a cobalt atom that cycles between oxidation states. Superoxide scavenging induces its oxidation, disabling activation of the enzymes methionine synthase and methylmalonyl-CoA mutase, disrupting gene expression and energy production. High-dosed vitamin B12 may be clinically used to reduce...article 2021
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Memelink, R. (author), Bongers, A. (author), Pasman, W. (author), van Rijmenam, M. (author), Wopereis, S. (author), Verlaan, G. (author), de Vogel Van den Bosch, J (author), Weijs, P.J.M. (author)Objectives. Weight loss is a key element in the treatment of obesity and type 2 diabetes (T2D), but also a risk factor for lean mass (LM) loss in older adults. We evaluated whether a whey protein drink enriched with leucine and vitamin D preserved LM during 3-month lifestyle intervention and whether effects sustained during 6 months follow-up...article 2020
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Kelly, J.M. (author), Matuszek, G. (author), van den Broek, T.J. (author), Huggins, G.S. (author), Smith, C.E. (author), Ordovas, J.M. (author), Wopereis, S. (author), Booth, S.L. (author)Inconsistent associations between lipids and circulating markers of fat-soluble vitamin and carotenoid status have been reported. The aim of this hypothesis-generating study was to examine the contribution of the LC-MS-based lipidome, characterized by lipid class, carbon count, and the number of unsaturated bonds, to the interindividual...article 2020
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- van Wouwe, J.P. (author), Lanting, C.I. (author) article 2017
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van den Broek, T.J. (author), Kremer, B.H.A. (author), marcondes Rezende, M. (author), Hoevenaars, F.P.M. (author), Weber, P. (author), Hoeller, U. (author), van Ommen, B. (author), Wopereis, S. (author)Background. Vitamins and carotenoids are key micronutrients facilitating the maintenance of health, as evidenced by the increased risk of disease with low intake. Optimal phenotypic flexibility, i.e., the ability to respond to a physiological challenge, is an essential indicator of health status. Therefore, health can be measured by applying a...article 2017
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Grimshaw, K. (author), Logan, K. (author), O'Donovan, S. (author), Kiely, M. (author), Patient, K. (author), van Bilsen, J. (author), Beyer, K. (author), Campbell, D.E. (author), Garcia-Larsen, V. (author), Grabenhenrich, L. (author), Lack, G. (author), Mills, C. (author), Wal, J.M. (author), Roberts, G. (author)Recommendations and guidelines on the prevention of food allergy have changed in recent decades. The aim of this review of the current evidence and ongoing studies is to provide a comprehensive and up to date picture of prevention of food allergy for healthcare professionals. The review was undertaken as part of the European Union funded...article 2017
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Souverein, O.W. (author), de Vries, J.H.M. (author), Freese, R. (author), Watzl, B. (author), Bub, A. (author), III Miller, E.R., (author), Castenmiller, J.J.M. (author), Pasman, W.J. (author), van het Hof, K. (author), Chopra, M. (author), Karlsen, A. (author), Dragsted, L.O. (author), Winkels, R. (author), Itsiopoulos, C. (author), Brazionis, L. (author), O'Dea, K. (author), van Loo-Bouwman, C.A. (author), Naber, T.H.J. (author), van der Voet, H. (author), Boshuizen, H.C. (author)Fruit and vegetable consumption produces changes in several biomarkers in blood. The present study aimed to examine the dose-response curve between fruit and vegetable consumption and carotenoid (alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, lutein and zeaxanthin), folate and vitamin C concentrations. Furthermore, a prediction...article 2015
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Raiten, D.J. (author), Sakr Ashour, F.A. (author), Ross, A.C. (author), Meydani, S.N. (author), Dawson, H.D. (author), Stephensen, C.B. (author), Brabin, B.J. (author), Suchdev, P.S. (author), van Ommen, B. (author), Ahluwalia, N. (author), Ahmed, T. (author), Allen, L. (author), Beck, M. (author), Blanchard, H. (author), Brindle, E. (author), Brown, K. (author), Calder, P. (author), Checkley, W. (author), Claycombe, K. (author), Coles, C. (author), Esamai, F. (author), Friis, H. (author), Gardner, E. (author), Grinspoon, S. (author), Guerrant, R. (author), Hellerstein, M. (author), Hunt, J. (author), King, J. (author), Klasing, K. (author), Kramer, B. (author), Koski, K. (author), Northrop-Clewes, C. (author), Pfeiffer, C. (author), Prentice, A. (author), Ramirez-Zea, M. (author), van Rheenan, P. (author), Rink, L. (author), Srinivasa, S. (author), Benn, C.S. (author), Stephensen, C. (author), Suchdev, P. (author), Sullivan, K. (author), Thurnham, D. (author), Varadhan, R. (author), Van Der Ven, A. (author), Walston, J. (author), Xia, J. (author)An increasing recognition has emerged of the complexities of the global health agenda-specifically, the collision of infections and noncommunicable diseases and the dual burden of over- and undernutrition. Of particular practical concern are both 1) the need for a better understanding of the bidirectional relations between nutritional status and...article 2015
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Weernink, M.G. (author), van Wijk, R.M. (author), Groothuis-Oudshoorn, C.G. (author), Lanting, C.I. (author), Grant, C.C. (author), van Vlimmeren, L.A. (author), Boere-Boonekamp, M.M. (author)Vitamin D insufficiency during pregnancy is associated with disturbed skeletal homeostasis during infancy. Our aim was to investigate the influence of adherence to recommendations for vitamin D supplement intake of 10 μg per day (400 IU) during pregnancy (mother) and in the first months of life (child) on the occurrence of positional skull...article 2014
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Genkinger, J.M. (author), Wang, M. (author), Li, R. (author), Albanes, D. (author), Anderson, K.E. (author), Bernstein, L. (author), van den Brandt, P.A. (author), English, D.R. (author), Freudenheim, J.L. (author), Fuchs, C.S. (author), Gapstur, S.M. (author), Giles, G.G. (author), Goldbohm, R.A. (author), Håkansson, N. (author), Horn-Ross, P.L. (author), Koushik, A. (author), Marshal, J.R. (author), McCullough, M.L. (author), Miller, A.B. (author), Robien, K. (author), Rohan, T.E. (author), Schairer, C. (author), Silverman, D.T. (author), Stolzenberg-Solomon, R.Z. (author), Virtamo, J. (author), Willett, W.C. (author), Wolk, A. (author), Ziegler, R.G. (author), Smith-Warner, S.A. (author)Pancreatic cancer has few early symptoms, is usually diagnosed at late stages, and has a high case-fatality rate. Identifying modifiable risk factors is crucial to reducing pancreatic cancer morbidity and mortality. Prior studies have suggested that specific foods and nutrients, such as dairy products and constituents, may play a role in...article 2014
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TNO Kwaliteit van Leven (author), Atuonwu, J.C. (author), van Straten, G. (author), van Deventer, H.C. (author), van Boxtel, A.J.B. (author)This work studies the controllability of heat-integrated zeolite adsorption dryers. Mean product moisture content, temperature and vitamin C concentration (representative of product quality) are considered as controlled variables. Set-point tracking and disturbance rejection controllability metrics are considered in addition to energy...article 2012
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Verschuren, L. (author), Wielinga, P.Y. (author), van Duyvenvoorde, W. (author), Tijani, S. (author), Toet, K. (author), van Ommen, B. (author), Kooistra, T. (author), Kleemann, R. (author)Chronic inflammation and proatherogenic lipids are important risk factors of cardiovascular disease (CVD). Specific dietary constituents such as polyphenols and fish oils may improve cardiovascular risk factors and may have a beneficial effect on disease outcomes. We hypothesized that the intake of an antiinflammatory dietary mixture (AIDM)...article 2011
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Park, Y. (author), Spiegelman, D. (author), Hunter, D.J. (author), Albanes, D. (author), Bergkvist, L. (author), Buring, J.E. (author), Freudenheim, J.L. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Harnack, L. (author), Kato, I. (author), Krogh, V. (author), Leitzmann, M.F. (author), Limburg, P.J. (author), Marshall, J.R. (author), McCullough, M.L. (author), Miller, A.B. (author), Rohan, T.E. (author), Schatzkin, A. (author), Shore, R. (author), Sieri, S. (author), Stampfer, M.J. (author), Virtamo, J. (author), Weijenberg, M. (author), Willett, W.C. (author), Wolk, A. (author), Zhang, S.M. (author), Smith-Warner, S.A. (author), TNO Kwaliteit van Leven (author)Objective: To evaluate the associations between intakes of vitamins A, C, and E and risk of colon cancer. Methods: Using the primary data from 13 cohort studies, we estimated study-and sex-specific relative risks (RR) with Cox proportional hazards models and subsequently pooled RRs using a random effects model. Results: Among 676,141 men and...article 2010
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Rouau, X. (author), Mateo-Anson, N. (author), Barron, C. (author), Chaurand, M. (author), Lullien-Pellerin, V. (author), Mabille, F. (author), Samson, M.-F. (author), Abecassis, J. (author), Hemery, Y. (author), TNO Kwaliteit van Leven (author)Wheat bioactive compounds (fibres, minerals, vitamins, antioxidants) are concentrated in grain outer layers, which constitute the bran fraction obtained after the milling process leading to the white flour. In order to improve the health value of the flours, whole grains can be processed or alternatively, bran fractions can be added to white...article 2010
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TNO Kwaliteit van Leven (author), Molag, M.L. (author), de Vries, J.H.M. (author), Duif, N. (author), Ocké, M.C. (author), Dagnelie, P.C. (author), Goldbohm, R.A. (author), van 't Veer, P. (author)The authors automated the selection of foods in a computer system that compiles and processes tailored FFQ. For the selection of food items, several methods are available. The aim of the present study was to compare food lists made by MOM2, which identifies food items with highest between-person variance in intake of the nutrients of interest...article 2010
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Dietary folate and folate vitamers and the risk of pancreatic cancer in the Netherlands cohort studyKeszei, A.P. (author), Verhage, B.A.J. (author), Heinen, M.M. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)An association between high intake of folate and reduced risk of cancer has been suggested by previous research. However, epidemiologic data from cohort studies regarding the relationship between dietary folate and pancreatic cancer are sparse and inconsistent. We examined the association between dietary folate intake and risk of pancreatic...article 2009
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Saffert, A. (author), Pieper, G. (author), Jetten, J. (author), TNO Kwaliteit van Leven (author)This work is the third and last part of a milk study evaluating the effect of package light transmittance on the vitamin content of milk, in this case on fortified UHT low-fat milk. The milk was stored under light with an intensity of 700 lux in polyethylene terephthalate (PET) bottles with varying light transmittance to monitor the changes in...article 2009
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van Dijk, C.E. (author), de Boer, M.R. (author), Koppes, L.L.J. (author), Roos, J.C. (author), Lips, P. (author), Twisk, J.W.R. (author), TNO Kwaliteit van Leven (author)Introduction: Studies on the association of vitamin D and bone mineral density (BMD) in adolescence and young adults have shown contrasting results. None of these studies have examined the course and baseline in vitamin D intake. The purpose of this study was to examine the association between baseline and the course of dietary vitamin D intake...article 2009